Protein

Protein accession
A0A5J6TDR2 [UniProt]
Representative
4613D
Source
UniProt (cluster: phalp2_37687)
Protein name
Hydrolase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MEGIMHARTITGAGALAVVTLLGVAVSPADAAASTTLRTKAYEVAKAQLGDRYVWGATGPSSFDCSGLTWYAYRQAGHTWARKTAHEQRRTQTVDITAAQRTRGDLIFFRPKGKSVYTHVGVYSGDGKMINAVNGRTYKGVVNRPVKDGYWDRYYVADYRRVA
Physico‐chemical
properties
protein length:163 AA
molecular weight:17912,1 Da
isoelectric point:9,95
hydropathy:-0,35
Representative Protein Details
Accession
4613D
Protein name
4613D
Sequence length
144 AA
Molecular weight
15537,74100 Da
Isoelectric point
10,46910
Sequence
MIAVTLAVAAFVALTYLRRSLPTSTIARAIASARAQIGKPYKWGAVGPDSFDCSGLMWFAWKQAGVSFARLTANELFNRLRRVSRADLQPGDMVFFGTAGNLHHVGLYVGNGQMVHAPNSKSTVKESPIASMSDFYAGGRLRAT
Other Proteins in cluster: phalp2_37687
Total (incl. this protein): 7 Avg length: 167,0 Avg pI: 9,94
Protein ID Length (AA) pI
4613D 144 10,46910
A0A2Z4QBH5 159 9,87419
A0A2Z4QBQ0 159 9,91338
A0A125V8N7 234 9,59826
A0A9E7TB59 155 9,87922
A0AAX4RAE8 155 9,91306
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_39666
6UgY6
 16 43,3% 120 1.020E-30
2 phalp2_20916
72mid
 3 45,5% 112 3.270E-29
3 phalp2_27434
4StvA
 61 36,5% 134 2.445E-26
4 phalp2_2843
8JxjE
 191 38,9% 113 2.753E-24
5 phalp2_29089
6VxI8
 38 39,8% 108 5.168E-24
6 phalp2_24590
56wtZ
 13 37,5% 128 5.168E-24
7 phalp2_24984
CFMj
 3 39,8% 123 1.648E-22
8 phalp2_12592
1nAeA
 3 46,5% 101 1.490E-21
9 phalp2_14699
6wXZL
 6 43,3% 90 2.041E-21
10 phalp2_13815
74q4c
 2 40,0% 100 2.795E-21

Domains

Domains [InterPro]
NLPC_P60
Representative sequence (used for alignment): 4613D (144 AA)
Member sequence: A0A5J6TDR2 (163 AA)
1 144 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00877

Taxonomy

  Name Taxonomy ID Lineage
Phage Streptomyces phage Araceli
[NCBI] 		2601641 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MN224564 [NCBI]
CDS location
range 50908 -> 51399
strand +
CDS
TTGGAGGGCATCATGCACGCTCGCACCATCACCGGAGCCGGAGCGCTCGCGGTCGTCACCCTGCTCGGGGTGGCGGTCTCCCCGGCCGACGCTGCGGCGTCCACCACGCTGCGCACGAAGGCGTACGAGGTGGCGAAGGCGCAGCTCGGGGACCGCTACGTCTGGGGCGCCACCGGGCCTTCGTCCTTCGACTGCTCGGGGTTGACGTGGTACGCCTACCGGCAGGCGGGCCATACCTGGGCGCGGAAGACCGCGCACGAGCAGCGCCGGACGCAGACCGTGGACATCACGGCCGCGCAGCGCACGCGGGGGGACCTGATCTTCTTCCGGCCGAAGGGCAAGAGCGTTTACACGCACGTCGGGGTGTACTCCGGCGACGGCAAGATGATCAACGCGGTGAACGGCCGGACGTACAAGGGCGTGGTGAACCGGCCGGTGAAGGATGGCTACTGGGACCGCTACTACGTGGCCGACTACCGGCGGGTTGCCTGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008234 cysteine-type peptidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (4613D) rather than this protein.
PDB ID
4613D
Method AlphaFoldv2
Resolution 91.46
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50