Protein

Protein accession
A0A5J6T572 [UniProt]
Representative
1QQ4D
Source
UniProt (cluster: phalp2_28453)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MADRVLENGIDVSRYQGNIDWKKVVKDNDNIKFVFIKATQGTGYKDPKLSANIKGSEAVGLDNGLYHYATFTSKASALAEAKWFVSQAGNYKFERGLVLDLEENRGGLGKTALTDAALAFLDYINSKGHKAVLYINKNYYDNYLDMSRILNKYEVWIARYNSFLNVEGADYWQYTDKGKVDGIAGYVDMNHSLDDGKTEKAGSTTPPKKVAATKPKARTKNSDGTYTVRSGDTLSEIAADFGVKASDLQKWNGIKNANVISVGQKLKLKGSTSSSSSSSTKTYTVKSGDSLSGIAAKYGTTVSKLQSLNGIKDPNFIKVGQKIKISGSSSSSSSKTITVKSGDTVSELAAKYGTTKEKIRSWNKLDSDYTIYAGQKLRVR
Physico‐chemical
properties
protein length:380 AA
molecular weight:41479,1 Da
isoelectric point:9,53
hydropathy:-0,55
Representative Protein Details
Accession
1QQ4D
Protein name
1QQ4D
Sequence length
598 AA
Molecular weight
66628,80950 Da
Isoelectric point
9,27379
Sequence
MAEVLKIVAGAGHGGGGTTPGKRTPDGEYEWDFNDIVADGFVDELSKYEGVQIRRVDDDDVSDGYEDIPLRDRVKEANSWGADYWFSFHHNALRGVWGDHTGTETFYWQGNPESKRVAQLVQDAMLEVYGLRDRGIKRGNHLYIIKNSNMPTILTEGGFMDSVIDIKVLRDSDKLYEAGKNVAKRFAEYKELKRKGKSDSKEKVKNLVSQDEFINFLKDGAIEGWKKYGILPSVSAAQAILESNWGKSELAVKANNLFGVKASDGWKGDKYLVETKEQDKNGNEFTVKAYFRKYESWSDSVEDHGTFFTSTPWREKNYATVIGEKDYKKQAKELQNSGYATDKQYANKLIRLIEQYDLYEWDKEAGISIPKKKSEKYQVVTSISGYKTAGDAKKRSNKATTVKSGSYYVYKKSNGMINVTSKDGVPGSWINPSDNKKKPTSSDGTYTVKSGDTLSGIAEKFNTTVDKLASLNGIKNKNLIRVGQKLKVSGSVSTTSSKTYTVKSGDTLSEIAQNHGTTVKQLQNANDIKNANLIRVGQKLTIPSGTSPKPSKEYHTVKSGDTVSELAQKYGSTTSQIKSWNNLKNANLIQVGQKLRVK
Other Proteins in cluster: phalp2_28453
Total (incl. this protein): 7 Avg length: 413,4 Avg pI: 9,44
Protein ID Length (AA) pI
1QQ4D 598 9,27379
A0A5J6T5D6 380 9,53031
A0A5J6T5S3 380 9,56390
A0A5J6T853 380 9,53044
A0A5J6TAQ8 380 9,56390
A0AA49X551 396 9,06124
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_14098
7ooYL
 2 33,9% 433 2.156E-51
2 phalp2_10537
7Yl5a
 2 27,3% 450 2.002E-25
3 phalp2_21214
19jI2
 2 22,5% 478 2.104E-09

Domains

Domains [InterPro]
Ami3
GLUCO
Unannotated
LysM
LysM
LysM
Representative sequence (used for alignment): 1QQ4D (598 AA)
Member sequence: A0A5J6T572 (380 AA)
1 598 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01476, PF01520, PF01832

Taxonomy

  Name Taxonomy ID Lineage
Phage Bacillus phage 031MP003
[NCBI] 		2601657 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MN176223 [NCBI]
CDS location
range 28520 -> 29662
strand +
CDS
ATGGCTGATAGAGTTTTAGAAAACGGAATTGACGTTTCACGATACCAAGGGAATATTGACTGGAAAAAGGTTGTCAAAGATAACGATAACATTAAATTCGTTTTCATCAAAGCAACACAAGGGACAGGCTATAAAGACCCCAAGCTTTCTGCAAACATTAAAGGCAGTGAAGCGGTAGGGCTGGACAACGGTCTATATCATTACGCAACTTTCACAAGTAAAGCAAGCGCACTAGCTGAAGCGAAATGGTTCGTATCCCAAGCTGGGAACTACAAGTTTGAAAGAGGGCTTGTTTTAGACTTGGAAGAGAACAGGGGAGGACTGGGGAAAACAGCCCTCACAGATGCCGCCCTAGCATTCCTTGACTATATCAATAGTAAAGGACATAAAGCGGTATTGTACATCAATAAGAACTATTATGACAACTATCTCGATATGTCCCGCATCCTGAACAAATACGAGGTGTGGATTGCACGATACAACTCTTTCTTGAATGTAGAAGGTGCTGATTATTGGCAATACACAGATAAAGGGAAAGTGGATGGCATTGCAGGGTATGTAGACATGAACCACTCTCTTGATGACGGAAAAACTGAAAAAGCTGGAAGCACAACCCCGCCGAAAAAAGTAGCGGCTACCAAACCTAAAGCACGCACCAAGAACTCAGACGGCACTTACACGGTTCGTTCAGGTGACACGCTCAGTGAGATTGCCGCAGACTTCGGGGTAAAAGCATCAGACCTACAAAAATGGAACGGCATTAAAAACGCCAATGTCATTTCCGTAGGTCAAAAACTGAAGCTGAAAGGCTCTACCTCTTCTTCATCCTCATCTAGCACCAAGACATACACAGTGAAGAGCGGCGATTCTTTAAGCGGCATTGCGGCAAAGTATGGGACAACCGTTTCTAAACTTCAGTCGCTAAACGGAATCAAAGACCCTAACTTCATCAAGGTGGGGCAAAAGATCAAAATATCAGGTTCGTCCTCTTCTTCGTCCAGTAAAACAATCACAGTCAAGTCAGGTGATACAGTTTCGGAATTAGCGGCTAAATACGGGACAACGAAAGAGAAAATTCGTTCTTGGAATAAATTAGATTCGGATTACACGATTTACGCAGGTCAAAAATTGAGAGTTCGATAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0008932 lytic endotransglycosylase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (1QQ4D) rather than this protein.
PDB ID
1QQ4D
Method AlphaFoldv2
Resolution 81.50
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50