Protein

Protein accession
A0A5J6T2W3 [UniProt]
Representative
7dXSl
Source
UniProt (cluster: phalp2_13831)
Protein name
LysM-like endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MAKFSSLISGTTPDHGKNRGKDEKKTRLIVHHWAGTAGGDTALMKPKGQNSRGDVSASYILYSDGRLIGQVSEDLSPWTTGQADWGSITVETQNAANGGIWPIDQRAKDKLAQLMADLSDRHGWGELKLGTNVRMHREFNATACPGPDMVNSLPAIIAKANQLRKGGSGSSGGGQPASGGTYTVSKGESLSSIASKYGTTWQVLQSLNNLSNPNKIYPGQKLVVPSAPSGGGSKPSQSLSDVAKAVLRGDYGNGATRVAKLRAAGYDPNEVQAEVNRQLYGNPKSSSGGVDIDGLARAVIRGDYGNGSERQRRLGSNYSAVQKRVNEILAGK
Physico‐chemical
properties
protein length:332 AA
molecular weight:34992,6 Da
isoelectric point:9,72
hydropathy:-0,60
Representative Protein Details
Accession
7dXSl
Protein name
7dXSl
Sequence length
124 AA
Molecular weight
13376,88390 Da
Isoelectric point
9,93034
Sequence
MARAQYWYDRMSGTKPAPTPPAKPTPPAPKPSANIDALADAVIRGEYGNGDERKRRLGSNYAAVQKRVNEKLAGGSPAKPSVNIDALTDAVIRGEYGNGEERKRRLGGNYAAVQKRVNEQLGIS
Other Proteins in cluster: phalp2_13831
Total (incl. this protein): 7 Avg length: 214,3 Avg pI: 9,84
Protein ID Length (AA) pI
7dXSl 124 9,93034
6YFOO 131 9,39480
7d1Kx 124 9,98759
DTNC 124 10,27711
A0A7G9A2Z0 332 9,75937
A0A976UDD4 333 9,81256
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_11177
5MkZE
 1 63,8% 83 2.103E-30
2 phalp2_14793
6ZbKm
 6 48,9% 98 2.369E-21
3 phalp2_38035
63Vjb
 2 46,6% 105 2.158E-20
4 phalp2_14081
8qOST
 4 50,0% 92 5.560E-20
5 phalp2_35526
OTLW
 2 41,9% 93 4.603E-18
6 phalp2_40105
8dhVu
 1 44,6% 94 2.517E-15
7 phalp2_29314
D4cL
 7 42,5% 94 4.726E-15
8 phalp2_9809
8mZun
 5 40,6% 96 4.284E-14
9 phalp2_10423
21i6d
 1 36,9% 84 4.637E-06

Domains

Domains [InterPro]
Disordered region
Unannotated
Unannotated
Representative sequence (used for alignment): 7dXSl (124 AA)
Member sequence: A0A5J6T2W3 (332 AA)
1 124 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Microbacterium phage ChickenKing
[NCBI] 		2652406 Ilzatvirus >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MN310543 [NCBI]
CDS location
range 18340 -> 19338
strand +
CDS
ATGGCTAAGTTCTCGAGCCTGATCTCGGGCACGACTCCGGACCACGGCAAGAACCGTGGGAAGGACGAGAAGAAGACGCGTCTCATCGTCCATCACTGGGCGGGTACGGCTGGCGGCGACACGGCTCTCATGAAGCCGAAGGGCCAGAACAGCCGGGGCGACGTGTCGGCTTCGTACATCCTCTACTCGGACGGTCGCCTCATCGGCCAGGTGTCCGAGGACCTGTCGCCGTGGACCACGGGTCAGGCTGACTGGGGTTCGATCACGGTCGAGACCCAGAACGCGGCGAACGGTGGCATCTGGCCCATCGACCAGCGTGCCAAGGACAAGCTCGCACAGCTCATGGCGGACCTCTCGGACCGTCACGGCTGGGGTGAGCTGAAGCTCGGCACCAACGTCCGGATGCACCGGGAGTTCAACGCGACTGCCTGCCCCGGTCCGGACATGGTCAACAGCCTGCCCGCCATCATCGCGAAGGCGAACCAGCTCCGCAAGGGTGGCTCCGGCTCGAGCGGCGGAGGTCAGCCTGCCAGCGGCGGCACCTACACCGTCTCCAAGGGCGAGTCACTCTCGAGCATCGCGTCCAAGTACGGAACGACCTGGCAGGTGCTCCAGTCGCTGAACAACCTGTCCAACCCGAACAAGATCTACCCCGGCCAGAAGCTGGTGGTGCCCTCGGCTCCGTCCGGCGGCGGCTCTAAGCCCTCGCAGTCCCTCAGCGATGTGGCCAAGGCAGTCCTCCGGGGCGACTACGGCAACGGGGCTACCCGCGTGGCGAAGCTCCGCGCCGCTGGCTACGACCCGAACGAGGTCCAGGCAGAGGTCAACCGCCAGCTCTACGGCAACCCGAAGAGCTCGAGCGGCGGGGTCGACATCGACGGTCTGGCCCGCGCGGTCATCCGTGGGGACTACGGCAACGGCTCGGAGCGCCAGCGTCGTCTCGGCTCCAACTACTCGGCCGTGCAGAAGCGCGTGAACGAGATTCTCGCAGGCAAGTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0008932 lytic endotransglycosylase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7dXSl) rather than this protein.
PDB ID
7dXSl
Method AlphaFoldv2
Resolution 68.31
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50