Protein

Protein accession
A0A5J6D7A1 [UniProt]
Representative
6UgY6
Source
UniProt (cluster: phalp2_39666)
Protein name
Peptidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MGKHAKPKKSAIRAATVAGTLGTTLGLALVAPSDAQAATYKGPEALKVVAAQKGDWYKWGATGPSRFDCSGLMLYSFKKVGKTIPRTTNEQYNKATKISAGNRRVGDLVFLYSGTNEYHVMMYAGSGYVWHAPRTGERVKKERLWTSHVRYGRL
Physico‐chemical
properties
protein length:154 AA
molecular weight:16885,2 Da
isoelectric point:10,14
hydropathy:-0,44
Representative Protein Details
Accession
6UgY6
Protein name
6UgY6
Sequence length
184 AA
Molecular weight
20165,93900 Da
Isoelectric point
11,81772
Sequence
MPHFIRITMATATAFGALALAPTGAQAATTTTAATVVPAAHPRLTKHQRKVRVAHRRHVRRNHEVARALRVAARQQGDPYRYGATGPNAFDCSGLMLYSFRAAGLHLPRTAAAQAGAVRHIARSRMRVGDLVFFTSGSHVYHVGIFDGWRHGARIIIHAPYTGARVRKEAIWTNSWFAGTERLA
Other Proteins in cluster: phalp2_39666
Total (incl. this protein): 16 Avg length: 155,1 Avg pI: 10,09
Protein ID Length (AA) pI
6UgY6 184 11,81772
A0A222YZA4 152 9,79824
A0A411B6A7 152 9,82964
A0A6M3T629 160 10,55220
A0A6M3T9D6 152 10,14856
A0A7G8LKC3 155 10,18486
A0A7G9UWJ1 153 9,85420
A0A7G9W1R1 153 9,85420
A0A890UYN8 152 9,82964
A0A8F2IW29 155 10,03858
A0AA49BTA1 152 9,91306
A0AA96H392 152 9,79824
A0AA96H5U8 152 9,91306
A0AA96H9S1 152 9,91306
A0AA96HJ68 152 9,82964
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_37687
4613D
 7 35,8% 117 1.526E-25
2 phalp2_20916
72mid
 3 43,2% 118 2.852E-25
3 phalp2_703
1Eboy
 9 34,0% 147 9.078E-19
4 phalp2_27467
7KKUL
 3 32,3% 164 9.078E-19
5 phalp2_24590
56wtZ
 13 35,3% 133 2.029E-17
6 phalp2_28415
1DMoi
 3 33,5% 146 3.307E-16
7 phalp2_19314
8g2bY
 25 28,0% 121 1.584E-09
8 phalp2_13021
4419T
 1 32,5% 123 3.313E-08

Domains

Domains [InterPro]
Disordered region
NLPC_P60
Representative sequence (used for alignment): 6UgY6 (184 AA)
Member sequence: A0A5J6D7A1 (154 AA)
1 184 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00877

Taxonomy

  Name Taxonomy ID Lineage
Phage Streptomyces phage Zuko
[NCBI] 		2601695 Zukovirus > Zukovirus zuko
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MN204493 [NCBI]
CDS location
range 40637 -> 41101
strand -
CDS
GTGGGTAAGCACGCCAAACCGAAGAAGTCCGCCATACGAGCCGCGACCGTTGCCGGCACGCTGGGTACGACGCTGGGCCTCGCCCTCGTCGCTCCGAGTGATGCGCAGGCCGCGACCTACAAGGGGCCGGAAGCTCTCAAGGTCGTGGCCGCTCAGAAGGGTGACTGGTACAAGTGGGGAGCCACCGGGCCGTCCCGGTTCGACTGCTCCGGGCTCATGCTGTACTCCTTCAAGAAGGTGGGCAAAACCATCCCGCGCACCACCAACGAGCAGTACAACAAGGCTACGAAGATCTCCGCCGGCAATCGCCGGGTGGGCGACCTCGTGTTCCTGTACTCGGGTACCAACGAGTACCACGTCATGATGTACGCCGGGAGCGGCTACGTCTGGCACGCGCCTCGTACTGGCGAGCGGGTCAAGAAAGAGCGCCTGTGGACGTCTCACGTGCGCTATGGGCGCCTCTAG

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008234 cysteine-type peptidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (6UgY6) rather than this protein.
PDB ID
6UgY6
Method AlphaFoldv2
Resolution 87.80
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50