Protein

Protein accession
A0A5H2TJX5 [UniProt]
Representative
7lm13
Source
UniProt (cluster: phalp2_23542)
Protein name
N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MYIENILKTRKLRIGLRAGHSPNCLGAIGLRNEHTTMMVYYKYVKECFEKYGHTVIDCNSTANTEKAEVYEGINKANNAGVDIFISLHMNSYNGKAFGVECLVANGSRVWDVAERICEEYSKIGFFNRGVKIGNQWEMKDLNAPNIIFETCFCDSQKDIDIWSPCPYETLTRALCHAVDPSIPLTDEPDYYRVVVQRFKTKEDAEKAESKIKNDLGLYCFTEKI
Physico‐chemical
properties
protein length:224 AA
molecular weight:25599,0 Da
isoelectric point:6,00
hydropathy:-0,37
Representative Protein Details
Accession
7lm13
Protein name
7lm13
Sequence length
531 AA
Molecular weight
58837,41050 Da
Isoelectric point
8,98942
Sequence
MATPIMGTSKATIEQCELFLHNVNPKAPYLANIYKKYCDIYGIKLEIAWVQMCLETNFLRYSDTSITTLDMHNYAGLGALDGNGRKQALKFNTKNEGVECHIQHLFAYCSRNNLPQQQLIDPRFKYVDRGCAINVEDLGSGKWASDKQYANKLLDLLGRLTNTKIEKKGDNVMSKGMISYDFGHMEGGEDTSANGILYEYSIVRNYGSVVVRELQKAGYTLVNCTPPNGRMSLSQSLSYRVNKANSSGSMLHLCFHANCYNGNAYGCEMEVASDSSARIGQSIQNEVVSSLGFANRGVKRPSLYVTRNTNMPCVLTEPFFIDNRGDCNKYNVEKLGCAIATGVLKALGNNYRPSTGGNNSSSSSSPSKPTAIVTASALNVREQKSTSSKILGVLSNNKSVEVYKVEGDWVHIYYPPHGGFISKQYVKLYNIPDSIVQKPNKPVEKKEEKKMDIILYFGYVDEYGANLLRDKLKLPVLSLADFKANTNLKNNVGRIYMVGGSEKPVSDTVLISSGGRYDTAQAVIEYIKKLK
Other Proteins in cluster: phalp2_23542
Total (incl. this protein): 6 Avg length: 325,2 Avg pI: 6,77
Protein ID Length (AA) pI
7lm13 531 8,98942
1btHY 524 8,51764
A0A385ISV1 224 5,99915
A0A977WLB5 224 5,62418
A0AAF0AF14 224 5,47271
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_31329
2etws
 8 27,3% 431 9.891E-30
2 phalp2_17729
7ikmD
 1 28,6% 332 1.408E-19
3 phalp2_30857
omqp
 3 25,8% 368 1.408E-19
4 phalp2_11791
82p55
 1 26,6% 375 3.692E-16

Domains

Domains [InterPro]
GLUCO
Ami3
SH3_3
Unannotated
Representative sequence (used for alignment): 7lm13 (531 AA)
Member sequence: A0A5H2TJX5 (224 AA)
1 531 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01520, PF01832, PF08239

Taxonomy

  Name Taxonomy ID Lineage
Phage Clostridium phage CPD7
[NCBI] 		2483608 Guelinviridae > Susfortunavirus > Susfortunavirus susfortuna
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MK017820 [NCBI]
CDS location
range 8348 -> 9022
strand +
CDS
ATGTATATAGAAAATATTTTAAAAACTAGAAAATTAAGAATAGGTTTAAGAGCGGGTCATTCTCCAAACTGTTTGGGAGCAATAGGTTTAAGAAATGAACATACTACCATGATGGTATATTATAAGTATGTTAAAGAATGTTTTGAGAAATATGGTCATACTGTAATAGATTGTAATTCAACCGCTAATACTGAAAAAGCAGAAGTTTATGAGGGTATAAATAAGGCTAATAATGCAGGTGTTGATATTTTTATTTCTCTTCATATGAACTCTTATAATGGTAAAGCCTTTGGGGTTGAGTGTTTAGTTGCTAATGGTTCAAGGGTTTGGGATGTTGCTGAAAGAATATGCGAGGAATATTCAAAAATTGGTTTCTTTAATAGAGGTGTAAAGATAGGTAATCAATGGGAAATGAAAGACTTAAATGCACCTAATATAATATTTGAAACTTGTTTTTGTGATAGTCAAAAAGACATTGATATATGGTCACCTTGTCCTTATGAAACTTTAACAAGGGCTTTATGTCATGCGGTCGACCCTTCAATACCTTTAACAGATGAACCGGACTATTACCGTGTGGTTGTTCAAAGATTTAAAACAAAGGAAGATGCTGAAAAAGCTGAAAGTAAAATAAAAAATGATTTAGGATTATATTGTTTCACCGAGAAAATATAG

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
A0A5H2TJX5
Method AlphaFoldv2
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (7lm13) rather than this protein.
PDB ID
7lm13
Method AlphaFoldv2
Resolution 87.07
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50