Protein

Protein accession
A0A5C1K8R3 [UniProt]
Representative
7PBFx
Source
UniProt (cluster: phalp2_31960)
Protein name
Site-specific RNA endonuclease
Lysin probability
99%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MKKAILALTMLSASVFSAEHHFSSVQLDNLQYAYQFGEQFTKDGKYKTHETRDKKGLGYIMAAIAWQESSAGINTSKNKKKHHAYGVFQNYLPTVRNRAAQNNWNLSDTEIKRMLSDRKHSARWAYIELSYWLNIHNGDIRKAISSYNAGWNVKAGNKYASQVIEKANYLKSHEILISG
Physico‐chemical
properties
protein length:179 AA
molecular weight:20477,9 Da
isoelectric point:9,72
hydropathy:-0,62
Representative Protein Details
Accession
7PBFx
Protein name
7PBFx
Sequence length
119 AA
Molecular weight
13581,42480 Da
Isoelectric point
9,58543
Sequence
MGYHLAAIAWIESRACENTGKGKKGHHAYGCWQVTVNSASARMDKSYSKRVVINKLESLRGGSKFAIHELEYWLDYHKGDLKKALASYNAGFKYTKKEARDYARMVNHTAKLLEEKQII
Other Proteins in cluster: phalp2_31960
Total (incl. this protein): 121 Avg length: 193,7 Avg pI: 9,73
Protein ID Length (AA) pI
7PBFx 119 9,58543
M9V198 215 9,55836
A0A0K2FHY9 213 9,56822
A0A1J0MH56 120 9,95503
A0A223LFC0 183 9,74009
A0A2S1PDX6 183 9,76459
A0A2S1PG72 183 9,59904
A0A2Z5ZCH0 182 9,65126
A0A6B9J4T1 173 10,09544
A0A6B9J3S6 179 9,71908
K8DVU6 211 9,49189
J7KES7 179 9,54095
E5EYR4 145 9,79386
E5EPS2 173 10,07881
J7I134 183 9,64326
A0A1B1IXF5 215 9,55836
A0A159B7R6 181 9,66692
A0A0A0Q3G3 183 9,35612
A0A5B9NJI1 181 9,74744
A0A1G4GQA5 213 9,51903
A0A4Y5TRZ9 179 9,71908
A0A0M3UL23 215 9,73661
D5JFG8 213 9,56822
A0A5B9NDW9 213 9,56822
A0A410T5W4 174 9,91409
A7XF46 196 9,97205
A0A6B9X582 196 9,94581
Q76XJ0 196 9,97205
Q19CR9 177 10,03007
E1A1M0 183 9,45327
A0A1W5N0F9 215 9,67253
I6YMG0 183 9,43355
A0A6B9STC3 173 10,13213
A0A0K1LPK8 213 9,56822
A0A0K1LQC3 213 9,56822
A0A1B1P8W7 181 9,68704
A0A345AUX5 173 10,13213
A0A385IIP2 173 10,09544
A0A386K8Z8 181 9,70754
A0A3B8DIS2 215 9,72011
A0A482G9U5 196 9,86477
A0A482GDB5 196 9,97205
A0A482GGJ4 196 9,97205
A0A482GL74 196 9,97205
A0A482MM99 196 9,99661
A0A4Y1NKH2 173 10,13213
A0A514A702 215 9,65738
A0A5B9N2S8 196 9,91790
A0A5P8PGE2 208 9,59768
A0A5Q2F3E3 181 9,74744
A0A650DG00 196 9,97205
A0A650EX21 173 10,03226
A0A6B9J4M7 173 10,06617
A0A6B9LNS1 196 9,97205
A0A6B9LWN7 173 10,15952
A0A6B9SQN4 196 9,97205
A0A6B9SVF3 196 9,91790
A0A6M3YJ24 215 9,49189
A0A6M3YT18 215 9,67253
A0A6M9Z5P1 173 10,06617
A0A7D3ULF7 173 10,15952
A0A7D7F3J1 196 9,97205
A0A7G9VY40 173 10,15952
A0A7T3N6J6 215 9,55836
A0A7T3N6Y9 215 9,67253
A0A7T3TLN6 215 9,62347
K4FBF4 215 9,62347
A0A7T8J1P0 173 10,00164
A0A193GZ34 213 9,56822
A0A1W5P0K6 170 9,71360
A0A5B9NHD8 213 9,56822
A0A6H0X287 213 9,51903
A0A7I8HRD9 170 9,71360
A0A7I8LPL6 213 9,56822
A0A7R8MNP5 213 9,56822
A0A7R8MQL1 213 9,56822
A0A7R8MQR2 213 9,56822
A0A7R8R8E2 213 9,56822
A0A7R8R8H9 213 9,56822
A0A7R8XFM7 213 9,56822
A0A7T8IWQ7 213 9,56822
A0A873WHY1 187 9,43290
A0A8A6NJR3 170 9,66125
A0A8E7KYH9 215 9,68832
A0A8F3C8W9 213 9,56822
A0A8T8L6H8 215 9,62347
A0A974MYP7 219 9,58511
A0A977PL03 213 9,56822
A0A9P0YBY4 196 9,92299
A0AA49X6J4 179 9,71908
A0AA94YF00 183 9,69419
A0AA94YNP1 183 9,54095
A0AAE8YRI7 187 9,62341
A0AAE9CJG8 213 9,56822
A0AAE9HQ80 215 9,50317
A0AAE9IJT5 215 9,62347
A0AAE9LB67 215 9,67253
A0AAE9LBX3 216 9,62347
A0AAE9TA80 196 9,89501
A0AAF0JG70 215 9,62347
A0AAU8B9Y5 128 9,91725
A0AAU8BAM9 128 9,75511
A0AAV1MMC3 213 9,51903
A0AAV2C764 196 9,92299
A0AAV2PGW5 173 9,96767
A0AAX3BR89 213 9,56822
A0AAX3BRB0 213 9,56822
A0AAX3DF66 181 9,68704
A0AAX3Y2X3 174 10,03291
A0AAX4FCI4 215 9,67253
A0AAX4GAC9 213 9,51903
A0AAX4GBU1 213 9,51903
A0AAX4GDC4 213 9,56822
A0AAX4GGI7 213 9,51903
A0AAX4GIC0 213 9,51903
A0AAX4H094 181 9,74744
A0AAX4M6L9 181 9,74744
A0AAX4MV32 170 9,71360
A0AB39C8Z9 213 9,51903
A0AB39U0P1 181 9,74744
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_21078
8KTfD
 154 51,3% 76 3.034E-33
2 phalp2_33501
7Btnk
 252 41,6% 120 1.230E-30
3 phalp2_21864
4xA7u
 35 35,0% 120 4.347E-23
4 phalp2_30113
3cbsX
 116 32,5% 123 2.003E-18
5 phalp2_2223
4hYd3
 1 29,7% 121 4.958E-11
6 phalp2_39450
7P5WC
 2 26,4% 136 1.419E-08
7 phalp2_20412
3cyww
 2 31,1% 109 4.975E-08
8 phalp2_7193
3ccpd
 1 22,8% 118 1.388E-05

Domains

Domains [InterPro]
Unannotated
Representative sequence (used for alignment): 7PBFx (119 AA)
Member sequence: A0A5C1K8R3 (179 AA)
1 119 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Klebsiella phage EI
[NCBI] 		2601625 Marfavirus >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MN106245 [NCBI]
CDS location
range 54208 -> 54747
strand -
CDS
ATGAAAAAAGCGATCCTGGCACTTACGATGCTTTCTGCATCTGTTTTTAGTGCTGAGCACCACTTCAGTAGTGTCCAACTCGATAATTTGCAATACGCATATCAATTCGGGGAACAATTCACTAAGGACGGTAAGTATAAAACTCACGAGACTCGTGATAAGAAAGGACTTGGCTACATTATGGCCGCGATAGCTTGGCAAGAGTCAAGTGCAGGCATTAACACCAGTAAGAATAAAAAGAAACACCACGCTTATGGAGTGTTTCAAAATTACTTGCCTACAGTTCGCAATAGGGCTGCACAAAATAACTGGAATCTTTCTGATACAGAAATCAAAAGAATGCTATCAGATCGTAAGCATTCGGCCCGCTGGGCGTATATTGAACTGAGTTATTGGTTAAATATACATAACGGAGATATTCGTAAAGCTATCTCTAGTTATAATGCGGGGTGGAACGTAAAGGCAGGTAATAAATACGCCTCCCAAGTTATAGAAAAGGCGAATTATCTTAAATCGCATGAAATTTTAATTAGTGGATAG

Gene Ontology

Description Category Evidence (source)
GO:0004519 endonuclease activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7PBFx) rather than this protein.
PDB ID
7PBFx
Method AlphaFoldv2
Resolution 94.16
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50