Protein

Protein accession
A0A514TX97 [UniProt]
Representative
3epNU
Source
UniProt (cluster: phalp2_40313)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MSDLLLPVGPRRMSSWEAHQHRVPRSTEPGTDFYCPIGTPVLAPASGVVYAVFNSIGPATGRWVGVDFDNGMRFRAMHLSRTLVRVGQRVRRGDRLGLSGASGYGEEDWSWNPNTGGSHVHVTLWPTHQTRFGYNPRTGKPYTIDFMRYADTSSPSGGGQGGSPPKPKPPITEEEEEDMKPFLIWKKNPNGTRQWALISGDLSRMVPIFKLDTANALGKLYGAATQVVESEWAGFVNASEIEVTLTEATEPA
Physico‐chemical
properties
protein length:252 AA
molecular weight:27671,8 Da
isoelectric point:7,03
hydropathy:-0,48
Representative Protein Details
Accession
3epNU
Protein name
3epNU
Sequence length
263 AA
Molecular weight
29300,19220 Da
Isoelectric point
5,73502
Sequence
MGYVRPVDPVGGRMSSWLAHTRRTTPSTEPGVDYYCPVGTPVRAAERGTVVDVGDSIMPATGRFVTIDLDDGRRVRYLHLLRRHVGVGNRVVRGQVIALSGATGYGEEDWSWNVAQTGGAHVHMTLWGFHGYRFGRYATLDPEQYMDRSAPAGGDPEPLEPGEEEEEMSFNPKIIHRNTGGDEWALVEPTLRGVASHERGYIVTTDRDEFRAWGRTWAKGGGMNSYSADVPRDEYIEIQQAAQRVHEAWCRTQAEIQRLANGS
Other Proteins in cluster: phalp2_40313
Total (incl. this protein): 22 Avg length: 256,4 Avg pI: 5,72
Protein ID Length (AA) pI
3epNU 263 5,73502
1FT92 241 4,96366
3OwBf 254 5,45833
4HLzp 241 4,65769
4f75Q 244 5,06875
5EDyY 251 4,59307
5i2IV 249 9,12100
5ioZX 266 5,75639
5ipoF 262 5,18147
5ke7n 261 4,98685
5kfN2 288 4,96173
5kfPz 263 4,74500
6PJoG 237 6,53736
6SDlt 247 6,12170
6UxSd 224 5,76765
7dBCN 316 5,24808
7dzAH 254 5,45833
7lK5m 238 4,92887
7zKLM 285 5,93708
A0A514TXN1 252 6,60210
A0A7L7SSH5 252 7,02890
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_30504
5hZOB
 2 42,2% 187 1.411E-46
2 phalp2_37829
4HRho
 7 40,8% 169 1.852E-43
3 phalp2_26965
4FwsI
 2 30,8% 230 2.245E-42
4 phalp2_29729
1mI3z
 7 36,9% 176 4.487E-40
5 phalp2_8157
6Tpcb
 26 27,4% 186 2.879E-12
6 phalp2_20430
3gGjy
 2 26,5% 181 5.546E-11
7 phalp2_16794
1fRle
 2 31,6% 183 3.246E-10
8 phalp2_40405
499XR
 8 25,5% 180 1.408E-09
9 phalp2_10578
7nGjI
 2 26,7% 161 3.390E-09
10 phalp2_7729
6TjZJ
 1 24,5% 208 4.682E-08

Domains

Domains [InterPro]
PET_M23
Disordered region
Representative sequence (used for alignment): 3epNU (263 AA)
Member sequence: A0A514TX97 (252 AA)
1 263 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01551

Taxonomy

  Name Taxonomy ID Lineage
Phage Microbacterium phage WaterT
[NCBI] 		2593342 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MN096357 [NCBI]
CDS location
range 30830 -> 31588
strand +
CDS
ATGTCTGACCTTCTCCTTCCGGTGGGTCCTCGAAGAATGAGTTCGTGGGAGGCTCATCAGCACCGCGTACCTCGTTCTACCGAGCCGGGGACGGACTTCTATTGCCCCATTGGTACTCCTGTTCTAGCCCCAGCGAGTGGTGTAGTCTACGCAGTATTCAACTCTATCGGACCCGCCACCGGGCGCTGGGTGGGCGTTGATTTCGATAACGGCATGAGGTTTCGCGCAATGCACCTGTCCCGAACTCTTGTACGAGTCGGCCAGCGGGTACGACGCGGCGATCGTCTGGGTCTTTCTGGAGCCTCCGGGTACGGGGAAGAAGACTGGTCCTGGAACCCTAATACGGGGGGATCGCACGTCCATGTTACCCTCTGGCCAACCCATCAGACGCGTTTTGGTTATAACCCCCGCACGGGTAAGCCTTACACAATTGATTTCATGCGTTATGCTGACACCTCAAGTCCCTCGGGTGGAGGACAAGGTGGCTCACCCCCGAAACCCAAACCGCCCATTACTGAAGAAGAGGAAGAAGACATGAAACCGTTCCTGATCTGGAAGAAGAATCCCAACGGGACCCGACAGTGGGCACTGATCTCCGGCGACCTGTCCCGGATGGTACCTATCTTTAAGCTCGATACTGCGAACGCGCTCGGGAAGCTGTATGGCGCTGCGACCCAGGTCGTGGAGTCGGAGTGGGCTGGGTTTGTGAACGCCTCCGAGATTGAGGTCACTCTAACCGAGGCAACCGAGCCCGCGTAA

Gene Ontology

Description Category Evidence (source)
GO:0004222 metalloendopeptidase activity molecular function None (UniProt)
GO:0005886 plasma membrane cellular component None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)
GO:0046872 metal ion binding molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (3epNU) rather than this protein.
PDB ID
3epNU
Method AlphaFoldv2
Resolution 71.66
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50