Protein

Protein accession
A0A514DDD7 [UniProt]
Representative
8MADT
Source
UniProt (cluster: phalp2_22360)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MTGTFWPNGSRSDVVPPKPGVASSGFRASSEYGWRFHPNDHEWRLHAGIDLIGWTTILSPSDGEVTYAGWNGGYGNLVEVTRANGDSFRMAHNRSINVFRGQRVSALQPLAIMGTTGNSTGVHCHFETRPGGGATIDPRDFMARQPVPGPSGGGSTTPTTPKPEEAIDMNSGVYYENGKNTIVYMVFNTESGWFHEFGQGTGGGAMPGEYNNALARALGTPSWAKITKGHADAIKRGLTAVQPRAIPSELTVDLDRAGVLTAAGLSA
Physico‐chemical
properties
protein length:267 AA
molecular weight:28376,2 Da
isoelectric point:6,71
hydropathy:-0,40
Representative Protein Details
Accession
8MADT
Protein name
8MADT
Sequence length
267 AA
Molecular weight
28314,13470 Da
Isoelectric point
6,70907
Sequence
MTGTFWPNGSRSDVVPPKPGVASSGFRASSEYGWRFHPNDHEWRLHAGIDLIGWTTILSPADGEVTYAGWNGGYGNLVEVTRANGDSFRMAHNRSINVFRGQRVSALQPLAIMGTTGNSTGVHSHFETRPGGGATIDPRDFMARQPVPGPSGGGSTTPTTPKPEEAIDMNSGVYYENGKNTLVYMVFNTESGWFHEFGQGTGGGAMPGDYNNALARALGTPSWAKITKGHADAIKRGLTAVQPRAIPSELTVDLDRAGVLAAAGLTA
Other Proteins in cluster: phalp2_22360
Total (incl. this protein): 6 Avg length: 268,0 Avg pI: 6,95
Protein ID Length (AA) pI
8MADT 267 6,70907
5inij 271 7,11024
A0A2Z4Q731 267 6,70907
A0A514DI35 269 8,03084
A0A6B9L658 267 6,44124
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_13843
7k2Ej
 3 50,0% 168 1.672E-41
2 phalp2_6940
2RX5W
 1 40,6% 197 3.096E-36
3 phalp2_1609
82pcH
 10 29,4% 197 2.046E-08

Domains

Domains [InterPro]
Unannotated
Disordered region
Representative sequence (used for alignment): 8MADT (267 AA)
Member sequence: A0A514DDD7 (267 AA)
1 267 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Microbacterium phage Cinna
[NCBI] 		2591215 Mementomorivirus >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MK937591 [NCBI]
CDS location
range 30234 -> 31037
strand +
CDS
ATGACCGGCACGTTCTGGCCGAACGGGAGCCGGTCGGATGTCGTGCCGCCGAAGCCGGGCGTCGCATCGAGCGGCTTCCGCGCATCGAGCGAGTACGGGTGGCGCTTCCACCCGAACGACCACGAGTGGCGCCTACACGCGGGCATCGACCTGATCGGCTGGACGACGATTCTCAGCCCCTCCGACGGCGAGGTGACCTACGCGGGCTGGAACGGCGGCTACGGCAACCTCGTGGAGGTGACGCGCGCGAACGGCGACTCGTTCCGCATGGCGCACAACCGGAGCATCAACGTCTTCCGCGGCCAGCGCGTGAGCGCCCTCCAGCCGCTCGCGATCATGGGCACGACCGGAAACAGCACCGGCGTGCACTGCCACTTCGAGACGCGGCCCGGAGGCGGCGCCACGATCGACCCGCGGGACTTCATGGCCCGCCAGCCCGTCCCCGGACCCTCCGGCGGCGGAAGCACGACCCCGACCACCCCGAAGCCCGAGGAGGCTATCGACATGAACAGCGGCGTCTACTACGAGAACGGGAAGAACACCATCGTCTACATGGTGTTCAACACCGAGAGCGGATGGTTCCACGAGTTCGGCCAGGGCACCGGCGGCGGCGCCATGCCCGGCGAATACAACAACGCCCTCGCGCGCGCGCTCGGCACGCCGTCGTGGGCGAAGATCACGAAGGGACACGCCGACGCGATCAAGCGCGGCCTGACCGCCGTACAGCCGCGAGCGATCCCGTCTGAACTGACGGTCGATCTCGACCGGGCGGGCGTGCTCACCGCCGCCGGGCTGTCGGCGTGA

Gene Ontology

Description Category Evidence (source)
GO:0004222 metalloendopeptidase activity molecular function None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (8MADT) rather than this protein.
PDB ID
8MADT
Method AlphaFoldv2
Resolution 65.22
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50