Protein

Protein accession
A0A509ER44 [UniProt]
Representative
5Knrs
Source
UniProt (cluster: phalp2_35161)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 97% (predicted by ML model)
Protein sequence
MTEKELRQSYVNAAVSYLGCKESNGSHKKIIDLYNSHKPLARNYAVKYTDSWCATFVSAMAIKTGLTDIIPTECGCGQMIQLFQKLGAWVENDAYRPSTGDVIFYDWDDNGVGDDTGWPEHVGIVVSVSGNTIKIIEGNKSDSVSYREIAVNGRYIRGYGVPEYSSKATSAGSGSGNGGGLKYSKGDIVNFTGSKHYASANATSGPSCKAGKAKVTDTAEGTKHPYHLIAVNGSGSTVYGWVNASDIAGASTAAASGSIAEGKTVKVKNSATKYATGQTIPSWVKSRKYTVQKIDGDRALLKEITSWVKISDLELA
Physico‐chemical
properties
protein length:316 AA
molecular weight:33660,3 Da
isoelectric point:8,73
hydropathy:-0,35
Representative Protein Details
Accession
5Knrs
Protein name
5Knrs
Sequence length
464 AA
Molecular weight
50361,33230 Da
Isoelectric point
6,48916
Sequence
MKGDDVKEFQNLVTNRGFSCGTIDGKYGEKSVSACKKFQSSAGLSADGICGPDTWNKLEGRRMLKLTSPLMKGDDVKEFQTKITNHGYNCGSIDSMYGEKAKAACISFQKAKGLSADGMCGDKTWAALEGRRMLKVTSPLMRGDDVKEFQTLVKNKGFNPGTIDSIYGNNSKSACVAFQKASGLSADGICGDKTWAALDSDSAPSVGRRLLKKTSPLMQGEDVKEFQTLVKSKGFDPGTIDGKYGDNSIAACKAFQGYAGLSVDGMCGDKTWAALDSDIKPYEPSESAPSEPTTGTEKELRESVVIEAKKYLGYKESDGSHKKIVDIYNSHSPLARGYKVKYTDSWCAVFVSVVSIQCGLTDIMPTECSCGRMIELYQKLGRWEENDAYVPNIGDIIMYDWDDSGKGDNTGWPEHVGIVTEVTGSTMKIIEGNKSDSVAYRTVSVNGKDIRGYCLPDYASKANK
Other Proteins in cluster: phalp2_35161
Total (incl. this protein): 12 Avg length: 368,7 Avg pI: 6,86
Protein ID Length (AA) pI
5Knrs 464 6,48916
3loBE 408 6,16978
61Z0Z 330 9,33001
65s56 330 9,28520
6oxwd 466 7,36130
6spwL 473 6,20997
6wmmn 317 5,73292
7MrVj 458 6,47279
80pLv 406 6,82275
A0A8S5LLV0 217 5,00754
A0A8S5SCW7 239 4,75801
Similar Clusters

No similar clusters were found for representative 5Knrs.

Domains

Domains [InterPro]
Disordered region
PG_1 CHAP
Representative sequence (used for alignment): 5Knrs (464 AA)
Member sequence: A0A509ER44 (316 AA)
1 464 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01471, PF05257

Taxonomy

  Name Taxonomy ID Lineage
Phage Roseburia phage Shimadzu
[NCBI] 		2570913 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
LR596903 [NCBI]
CDS location
range 22136 -> 23086
strand +
CDS
ATGACAGAAAAAGAATTAAGACAGAGCTACGTCAATGCAGCCGTTTCCTATCTGGGCTGCAAGGAAAGCAACGGCAGCCACAAGAAAATTATTGATCTTTACAATAGCCACAAGCCCCTCGCCAGAAACTACGCCGTAAAATATACGGACTCATGGTGCGCGACTTTTGTCTCAGCTATGGCTATTAAAACGGGACTTACTGACATTATCCCGACCGAGTGCGGCTGCGGCCAGATGATCCAGCTTTTCCAGAAGCTCGGCGCATGGGTAGAAAATGACGCATACAGACCGAGCACCGGCGACGTTATTTTTTACGACTGGGACGACAACGGAGTCGGCGACGATACCGGCTGGCCTGAGCATGTCGGCATTGTAGTGAGCGTATCAGGCAACACGATCAAGATTATCGAGGGAAACAAGAGCGACTCAGTAAGCTATCGCGAAATTGCTGTAAACGGCCGCTATATTAGAGGCTACGGAGTGCCTGAGTACAGCAGCAAGGCAACCAGCGCCGGATCTGGATCTGGCAACGGTGGAGGTCTGAAATACTCAAAGGGTGATATTGTAAACTTTACCGGATCCAAGCACTACGCAAGTGCGAACGCTACCAGCGGTCCTTCCTGCAAGGCTGGAAAAGCAAAGGTAACAGACACCGCAGAGGGTACAAAGCACCCTTACCACCTGATTGCAGTCAATGGATCGGGATCGACCGTTTACGGCTGGGTAAATGCCTCAGACATTGCGGGAGCCTCTACTGCTGCCGCCTCTGGCTCTATTGCGGAGGGCAAAACAGTCAAGGTAAAGAACTCGGCCACAAAGTACGCAACCGGCCAGACGATCCCGAGCTGGGTGAAGTCCAGAAAATACACGGTACAGAAAATCGACGGAGATCGCGCCCTCTTGAAAGAGATCACAAGCTGGGTGAAAATCTCCGATCTTGAATTAGCATAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (5Knrs) rather than this protein.
PDB ID
5Knrs
Method AlphaFoldv2
Resolution 89.98
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50