Protein

Protein accession
A0A4Y6ED97 [UniProt]
Representative
7zQ20
Source
UniProt (cluster: phalp2_428)
Protein name
Lysin A
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MADVKGGYLRPTPAGGISSSWQAHKDRRPPAFPGPSQEPGTDIACAYGTTLVAPEDGVVVEIKTSNSGATGRFITIDLNDGRRVRYLHLSAVLVTSGKRVTRGQAVARSGASANGRDWGVGAHVHVTLWDFHKYVFGPNGTMDFMPQIGADNDGGGLTYSQEVANQQAWMNQARGEKLVVDGYRGGFTIAAIKRYQTFLGVKADGVWGANTQAAHQKYYDSLQTPAPSGHVGGVNDLASIGDVRGLQKIAKLYGYAGRIDNDWGDGSKRGFQRFLDQNYGGSLATWLRSKWGYKDADNIWGPNMKAAAARASVANMAAL
Physico‐chemical
properties
protein length:319 AA
molecular weight:34167,8 Da
isoelectric point:9,45
hydropathy:-0,41
Representative Protein Details
Accession
7zQ20
Protein name
7zQ20
Sequence length
323 AA
Molecular weight
35484,45780 Da
Isoelectric point
9,17703
Sequence
MPDVKGGYLRPTTTPTVSCSWQCHRDRPTPSTEPGTDFACAYGSQLFAPEDGVIVDVKTSTSGATGRYITIDLNDGQRIRLLHLKSVVVGKGTRVTRGQLIAYSGASGFGKEWGYGAHVHVTLWASHGYTFGKNATLDFFKQMGADNDGNMPVPSELVKAEQMFLNVAQGEKLTVDGYLGDLTRAAIKRYQQYLTGRGWYSGKIDGDWGAGTQAGHEKRYAEWVAQTQAPPSPQYHNVTLDDIASIGNVEGLQKIARLYLAQSVDNRWGDKSKRGLQMFLNANYGGSLVHWLRSKWGYVGNDQFGPVMKAALQRANEANRRAL
Other Proteins in cluster: phalp2_428
Total (incl. this protein): 48 Avg length: 314,2 Avg pI: 9,04
Protein ID Length (AA) pI
7zQ20 323 9,17703
4TngX 334 9,94349
5aokO 292 8,53337
5hQM9 329 6,63023
5hQQi 328 9,28275
5i0de 324 8,60377
5i12p 324 8,82155
6QWVv 304 10,05386
6S5Gk 316 9,14163
6S6U9 275 7,20999
6Sih4 291 5,87564
6SxXh 293 5,30515
6W8SL 275 9,29778
7Ad60 323 9,66628
7Aef2 313 9,42426
7cKqV 316 9,72926
7pspt 316 9,64823
7xj0J 300 9,75402
7yyok 338 4,75006
7zQ2S 319 9,40189
8Lx6m 315 9,36817
A0A4D6T9C0 323 9,17703
A0A386KPJ2 323 9,66628
A0A4Y6EE89 313 9,42426
A0A4Y6EB99 319 9,40189
A0A6M3TB54 315 9,36817
A0A3Q9RAN6 319 9,45476
A0A5J6T6X6 315 9,36817
A0A6M3T017 323 9,17703
A0A6M3T1A2 323 9,17703
A0A6M3T3H9 321 9,40189
A0A6M3T614 319 9,45476
A0A7G3VCX0 287 9,63288
A0A7G9A0H2 319 9,45476
A0A7G9A153 323 9,19005
A0A7G9UVN1 322 9,45998
A0A7L7SJ19 322 9,28353
A0A7T0M178 315 9,35335
A0A7T3KCE4 322 9,55629
A0A7T7Z8V0 286 9,61109
A0A7T7Z8W5 286 9,51574
A0A890UWB2 322 9,55629
A0A9E7DSF0 322 9,55629
A0A9E7J3Z5 315 9,35335
A0A9E7TW79 322 9,55629
A0AA96H6E5 315 9,42903
A0AAX4NP29 323 9,17703
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_11679
1MMvC
 116 31,3% 217 1.034E-34
2 phalp2_25483
3axoQ
 3 31,3% 233 1.491E-27

Domains

Domains [InterPro]
PET_M23
Unannotated
Unannotated
Representative sequence (used for alignment): 7zQ20 (323 AA)
Member sequence: A0A4Y6ED97 (319 AA)
1 323 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01551

Taxonomy

  Name Taxonomy ID Lineage
Phage Microbacterium phage LilyLou
[NCBI] 		2590876 Tinytimothyvirus > Tinytimothyvirus alex44
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MK894438 [NCBI]
CDS location
range 38251 -> 39210
strand +
CDS
ATGGCAGATGTCAAGGGCGGTTACCTTCGCCCCACTCCTGCTGGAGGGATCAGCTCCAGCTGGCAAGCACACAAGGATCGTCGACCCCCGGCGTTCCCCGGCCCGTCGCAGGAGCCTGGTACCGACATCGCGTGCGCGTACGGCACCACGCTCGTCGCACCCGAGGACGGTGTCGTGGTCGAGATCAAGACCTCGAACAGCGGCGCGACCGGTCGCTTCATCACGATCGACCTGAACGATGGACGGCGCGTGCGCTACCTTCATCTGTCGGCGGTGCTCGTGACCAGTGGTAAGCGCGTCACGCGCGGTCAGGCGGTCGCTCGCTCCGGTGCGTCGGCCAACGGTCGCGACTGGGGCGTCGGCGCTCACGTCCACGTCACGCTGTGGGACTTCCACAAGTATGTCTTCGGTCCGAACGGCACGATGGACTTCATGCCTCAGATCGGAGCGGACAATGACGGCGGTGGCCTGACGTACAGCCAGGAGGTCGCGAACCAGCAGGCTTGGATGAACCAGGCCCGTGGCGAGAAGCTCGTCGTCGACGGCTACCGTGGTGGGTTCACCATCGCGGCGATCAAGCGTTACCAGACGTTCCTCGGCGTCAAGGCCGACGGCGTCTGGGGCGCGAACACCCAGGCGGCTCACCAGAAGTACTACGACTCGCTGCAGACCCCGGCTCCGTCCGGACACGTCGGCGGGGTCAACGATCTCGCATCGATCGGCGACGTTCGTGGTCTTCAGAAGATCGCGAAGCTGTACGGCTACGCGGGCAGGATCGACAACGACTGGGGTGATGGCTCGAAGCGCGGCTTCCAGCGTTTCCTCGACCAGAACTACGGCGGCTCGCTCGCAACGTGGCTCCGGTCGAAGTGGGGATACAAGGATGCCGACAACATCTGGGGGCCGAACATGAAGGCGGCTGCTGCTCGGGCGTCCGTCGCGAACATGGCGGCGCTGTAA

Gene Ontology

Description Category Evidence (source)
GO:0004222 metalloendopeptidase activity molecular function None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7zQ20) rather than this protein.
PDB ID
7zQ20
Method AlphaFoldv2
Resolution 89.56
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50