Protein

Protein accession
A0A4Y5FE66 [UniProt]
Representative
5tR7x
Source
UniProt (cluster: phalp2_18353)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MPRMDMVDTSNNNGYMNVDNWRSMKKRGVKAMVAKLSEGTYFVDKTAAYSIANALKAGLYVNGYHFARFTTVDGAKREAQMAVRCALGAGLGKNAVIVLDFEATNSGWNQNAKIVKAWINEVHRLGYPKTDVYTMGSWINSVPLNNSGRGGWVANYPYNPSGFNLYTGYNGWQWTSSMKFAGCAGRFDVSQMYSDYYYGESAKKKKHKKAIYYRYNPKYVYSRSSINSYTDKAFKHKAKSYPAKQIFHVKRVVKYGKITRFELFNGKYITSNLNFVNRLYYSLSGGVKVVKSVKGTHRFKDVGLKKVVDWFPAGTEFSVKEVVKYGEVTRIKLENGMFISANKLINSFVE
Physico‐chemical
properties
protein length:350 AA
molecular weight:39736,1 Da
isoelectric point:9,88
hydropathy:-0,44
Representative Protein Details
Accession
5tR7x
Protein name
5tR7x
Sequence length
411 AA
Molecular weight
45782,00890 Da
Isoelectric point
9,32833
Sequence
LRFKKIILGAAIIVAPFLWSQKANAAMTQNSTQPRTDMVDVSSNNGYVSVSDYQQMRAQGVKSVVVKATEGTTYKNPYAKEQAQNADKAGLSINFYHFSHFTSVSDAQAEANYFADYVQTITSDRHVVMVNDEESITSTWYTFAQNNLFNSAFTKQLNQRGYYSTDIYSSASWFNYRFSADNANKGWVAAYPSVPTGTRYSTNNNWQWGSDFQFWNMLGRNFDVSQNYNDKYYHVGTSNASATAQAIKNGTATATTSSLSVGDTVYIKTAANKYYGSSTSIPKFVKNKNYHVLSVSGNRVVIREILSAVNRTDVVKVNTSTSTSTGSSALPSGVHAQNGTFTPNQRLMVWHGAGVSPTYQYYYSGESIKYVGYIDNWSAGYRYVVYKGASGNWCYVADRHLSPNYMLGYAR
Other Proteins in cluster: phalp2_18353
Total (incl. this protein): 6 Avg length: 387,8 Avg pI: 9,33
Protein ID Length (AA) pI
5tR7x 411 9,32833
5oNF0 419 9,23473
7g5i7 414 8,56754
7iNqs 410 9,15021
D6PSS2 323 9,83841
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_17635
6JmE3
 482 35,2% 289 2.911E-49

Domains

Domains [InterPro]
Disordered region
GH25
Unannotated
Unannotated
Representative sequence (used for alignment): 5tR7x (411 AA)
Member sequence: A0A4Y5FE66 (350 AA)
1 411 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183

Taxonomy

  Name Taxonomy ID Lineage
Phage Lactobacillus phage 3-SAC12
[NCBI] 		2510940 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MK504442 [NCBI]
CDS location
range 23992 -> 25044
strand +
CDS
ATGCCTAGAATGGATATGGTCGACACGTCAAACAACAATGGTTACATGAATGTTGATAATTGGCGTTCAATGAAAAAACGTGGCGTAAAAGCTATGGTTGCTAAGTTATCAGAGGGAACGTACTTCGTTGATAAAACTGCAGCATATAGCATTGCTAATGCGTTAAAAGCCGGACTATACGTAAACGGCTACCACTTTGCACGATTTACAACGGTAGATGGTGCAAAACGCGAAGCCCAAATGGCTGTTCGGTGTGCACTGGGGGCTGGATTAGGTAAGAACGCTGTAATCGTTTTGGATTTTGAAGCTACCAACTCTGGTTGGAATCAGAATGCTAAAATCGTAAAGGCTTGGATTAACGAAGTACACCGTCTTGGCTATCCTAAAACCGACGTTTACACCATGGGCAGCTGGATTAATTCAGTTCCATTAAACAACTCTGGCCGTGGTGGCTGGGTAGCTAACTACCCTTATAACCCGTCAGGATTTAATCTCTATACTGGATATAACGGCTGGCAATGGACGTCAAGCATGAAATTTGCAGGCTGTGCAGGTCGCTTCGACGTGTCACAGATGTATTCTGATTACTATTATGGTGAGTCAGCTAAGAAGAAGAAGCACAAAAAGGCTATTTACTATCGTTACAATCCTAAATATGTTTACAGCCGATCTTCAATCAACTCATATACTGACAAAGCGTTCAAGCATAAGGCTAAATCTTATCCAGCAAAGCAGATTTTTCATGTTAAGCGAGTTGTAAAATATGGCAAGATAACGCGGTTTGAGCTGTTTAATGGTAAATATATTACCAGTAACCTAAACTTCGTAAATCGATTATATTACAGCTTATCCGGTGGGGTTAAAGTCGTCAAATCAGTTAAAGGAACTCATCGCTTTAAAGATGTGGGACTTAAAAAAGTTGTTGATTGGTTCCCAGCCGGTACGGAATTCTCGGTAAAAGAAGTCGTTAAATATGGCGAAGTAACTAGAATTAAATTGGAAAACGGCATGTTTATTAGTGCCAATAAATTGATTAACTCATTTGTTGAATAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (5tR7x) rather than this protein.
PDB ID
5tR7x
Method AlphaFoldv2
Resolution 80.36
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50