Protein

Protein accession
A0A4Y1NWV0 [UniProt]
Representative
29dlo
Source
UniProt (cluster: phalp2_10448)
Protein name
Lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 97% (predicted by ML model)
Protein sequence
MKPEWDAYHIAITKTHIKSEEGYKLEAYKCTEGYLTGGYGHRIMDGEAIPSTKKGWVEIFEKDYSKAENGAQELLMLSENLHPNAFGIVIEMCYQMGSYGVSKFKKFLNALNQEQPDYVEASKEMLDSKWAKQTPNRANRMSERMAEIATKIFG
Physico‐chemical
properties
protein length:154 AA
molecular weight:17602,9 Da
isoelectric point:6,11
hydropathy:-0,64
Representative Protein Details
Accession
29dlo
Protein name
29dlo
Sequence length
93 AA
Molecular weight
10556,94190 Da
Isoelectric point
4,92569
Sequence
MDIVKARIKAHEGYRLEPYKDTLGFLTGGWGHKILGGEEVPESVEGWQELFDKDFDIALKGANSLIQEHLENTLYSDLPQIKKSIIQSILIEM
Other Proteins in cluster: phalp2_10448
Total (incl. this protein): 9 Avg length: 121,0 Avg pI: 5,17
Protein ID Length (AA) pI
29dlo 93 4,92569
1t98K 141 5,24660
1xqm1 141 5,26525
22A9V 102 5,14770
3EfFt 93 5,04153
4P8PN 83 4,69492
7IVos 141 5,02311
8kJoh 141 5,11900
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_21661
31ima
 875 44,4% 99 3.158E-14
2 phalp2_3294
2PG3y
 294 42,0% 69 4.641E-11
3 phalp2_10773
3ISMN
 265 32,2% 90 2.035E-05
4 phalp2_32125
6B6mf
 35 34,3% 64 3.832E-05
5 phalp2_37777
4xRBI
 75 29,7% 74 3.832E-05
6 phalp2_10898
4A8EL
 88 30,7% 78 5.258E-05
7 phalp2_26644
2b0IA
 24 31,5% 73 3.505E-04
8 phalp2_35600
1fedL
 106 36,2% 58 6.594E-04
9 phalp2_31530
48EM7
 20 27,6% 76 9.043E-04

Domains

Domains [InterPro]
Unannotated
Representative sequence (used for alignment): 29dlo (93 AA)
Member sequence: A0A4Y1NWV0 (154 AA)
1 93 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Pelagibacter phage HTVC109P
[NCBI] 		2283019 Autographiviridae > Pelagivirus >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MH598805 [NCBI]
CDS location
range 39975 -> 40439
strand +
CDS
ATGAAACCAGAATGGGACGCATACCACATAGCTATAACAAAAACTCATATCAAATCTGAAGAGGGTTATAAGCTAGAAGCCTATAAATGCACCGAAGGATACTTAACAGGTGGATACGGACATAGAATAATGGACGGAGAAGCTATACCTTCAACTAAAAAAGGTTGGGTAGAGATTTTTGAGAAAGACTACAGTAAAGCAGAGAATGGTGCTCAGGAATTACTTATGCTAAGTGAGAACTTACACCCTAATGCTTTTGGTATCGTTATTGAAATGTGTTATCAAATGGGTAGTTATGGTGTCTCTAAGTTCAAAAAGTTTCTTAATGCTCTTAATCAGGAGCAACCAGACTATGTAGAAGCGTCTAAAGAGATGTTAGATAGTAAATGGGCTAAACAAACGCCTAACAGAGCTAATAGAATGTCTGAAAGAATGGCAGAAATAGCTACTAAAATATTTGGTTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		RuleBase:RU003788

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (29dlo) rather than this protein.
PDB ID
29dlo
Method AlphaFoldv2
Resolution 89.38
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50