Protein

Protein accession
A0A4D6AP36 [UniProt]
Representative
4y86g
Source
UniProt (cluster: phalp2_31615)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 97% (predicted by ML model)
Protein sequence
MATYQEYKSRSNGNAYDIDGSFGAQCWDGYADYCKYLGLPYANCTNTGYARDIWEQRHENGILNYFDEVEVMQAGDVAIFMVVDGVTPYSHVAIFDSDAGGGYGWFLGQNQGGANGAYNLVKIPYSATYPTAFRPKSFKNAVTVTDNTGLNKGDYFIDVSAYQQADLTTTCQQAGTTKTIIKVSESIAWLSDRHQQQANTSDPIGYYHFGRFGGDSALAQREADLFLSNLPSKKVSYLVIDYEDSASADKQANTNAVIAFMDKIASAGYKPIYYSYKPFTLNNIDYQKIIAKYPNSIWIAGYPDYEVRTEPLWEFFPSMDGVRWWQFTSVGVAGGLDKNIVLLADDSSKMDIPKVDKPQELTFYQKLATNTKLDNSNVPYYEATLSTDYYVESKPNASSADKEFIKAGTRVRVYEKVNGWSRINHPESAQWVEDSYLVNATDM
Physico‐chemical
properties
protein length:443 AA
molecular weight:49644,5 Da
isoelectric point:4,83
hydropathy:-0,46
Representative Protein Details
Accession
4y86g
Protein name
4y86g
Sequence length
120 AA
Molecular weight
13176,50440 Da
Isoelectric point
4,79007
Sequence
MASYNAFKNLVLGKAFDLDGAFGAQCWDGYAKYCKYLGYSYANCQASGYVKDIYTQRKSNGMLNNFNEVSILQAGDVVVFKEDPTWTPSSHIAIFDSDIDGVYGYFLGQNQGGANGAFNL
Other Proteins in cluster: phalp2_31615
Total (incl. this protein): 15 Avg length: 330,7 Avg pI: 5,29
Protein ID Length (AA) pI
4y86g 120 4,79007
3WK2H 125 5,43042
41bxe 163 7,65754
699LN 152 5,09496
8nFhO 160 6,49206
A0A4D6AEL3 443 4,82946
A0A4D6B3T7 448 4,61279
A0A4D6B635 447 4,83242
J7KH48 443 4,87584
A0A3B8DM02 443 4,82946
Q8HA43 443 4,82946
A0A3B8DYV1 443 4,78700
A0A3B8E250 447 4,86374
A0A8S5T0Q0 241 6,59448
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_24703
6bxM0
 24 62,6% 123 3.984E-60
2 phalp2_26341
1gBcI
 110 34,6% 124 2.510E-20
3 phalp2_32947
3WJ00
 2 32,5% 89 1.261E-16
4 phalp2_29001
6tZ05
 5 33,3% 96 5.682E-12
5 phalp2_18914
23zaq
 3 29,1% 96 5.141E-11
6 phalp2_3543
4zM0o
 163 31,3% 99 9.642E-11
7 phalp2_24452
4BMZo
 66 31,0% 103 3.390E-10
8 phalp2_13673
5Vryf
 1 26,7% 86 8.702E-10
9 phalp2_22612
1LHfD
 16 27,7% 119 1.177E-06
10 phalp2_9151
6w5gn
 2 23,9% 92 3.005E-06

Domains

Domains [InterPro]
Unannotated
Representative sequence (used for alignment): 4y86g (120 AA)
Member sequence: A0A4D6AP36 (443 AA)
1 120 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Streptococcus phage Javan7
[NCBI] 		2548303 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MK448829 [NCBI]
CDS location
range 34755 -> 36086
strand +
CDS
ATGGCAACTTATCAAGAATATAAAAGCAGGTCAAATGGTAACGCTTATGATATTGATGGGTCTTTCGGTGCACAATGTTGGGATGGCTACGCAGATTACTGTAAGTATCTAGGACTGCCATACGCAAACTGTACAAATACAGGATACGCAAGGGATATATGGGAGCAACGTCACGAAAATGGTATCTTAAACTATTTTGATGAAGTGGAAGTTATGCAAGCTGGTGATGTTGCTATTTTTATGGTTGTTGACGGTGTAACGCCTTACAGTCATGTAGCAATTTTTGACAGCGATGCAGGAGGCGGATATGGCTGGTTTTTGGGGCAAAATCAAGGGGGTGCTAACGGTGCATACAATCTTGTAAAAATCCCATATTCAGCAACTTATCCAACAGCCTTTAGACCAAAAAGCTTTAAAAACGCTGTTACTGTAACTGATAATACCGGTTTAAATAAAGGTGATTACTTTATCGATGTATCGGCTTATCAACAAGCAGATTTAACAACGACTTGTCAGCAGGCGGGCACTACAAAAACGATTATCAAGGTATCCGAGTCAATTGCTTGGCTGTCTGACAGACATCAACAACAAGCAAACACAAGCGACCCAATTGGCTATTACCACTTTGGACGTTTTGGCGGTGATAGTGCTTTAGCGCAACGGGAAGCAGACTTATTTTTGTCTAACTTACCAAGCAAAAAAGTATCATACTTAGTCATTGACTATGAAGATTCCGCAAGCGCAGACAAGCAAGCTAACACAAATGCAGTTATTGCATTTATGGATAAAATCGCTAGCGCTGGATATAAGCCTATTTATTACAGCTATAAACCATTTACGCTTAATAATATTGATTATCAGAAAATTATCGCTAAGTACCCTAATAGCATTTGGATAGCTGGTTATCCAGACTACGAAGTACGAACAGAGCCGCTGTGGGAGTTCTTCCCTTCAATGGATGGTGTTCGCTGGTGGCAGTTTACAAGTGTAGGAGTAGCAGGTGGTTTAGATAAAAATATTGTGTTGTTAGCAGATGATAGTAGCAAAATGGATATACCTAAGGTTGATAAGCCACAAGAACTTACTTTTTATCAAAAACTAGCTACTAACACTAAATTAGACAACTCAAATGTACCTTATTACGAAGCAACTCTTAGCACAGACTATTATGTAGAGTCTAAGCCAAACGCAAGTAGCGCTGATAAAGAATTTATCAAGGCAGGAACTCGTGTAAGAGTTTATGAAAAAGTGAATGGATGGTCACGCATTAACCATCCAGAGTCGGCGCAATGGGTAGAAGATAGCTACTTAGTTAACGCAACAGATATGTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

PDB ID
upi000009c45b_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (4y86g) rather than this protein.
PDB ID
4y86g
Method AlphaFoldv2
Resolution 95.80
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50