Protein

Protein accession
A0A481UYU3 [UniProt]
Representative
3heUl
Source
UniProt (cluster: phalp2_6864)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MRTSQRGIDLIKSSEGLRLSAYQDSVGVWTIGYGTTRGVTRYMTITVEQAERMLANDIQRFEPELDKLVKVPLNQNQWDALMSFVYNLGSANLASSTLLKLLNKGDYRGAADQFPRWVNAGGKRLEGLVKRRAAERALFLEPLS
Physico‐chemical
properties
protein length:144 AA
molecular weight:16181,3 Da
isoelectric point:9,69
hydropathy:-0,34
Representative Protein Details
Accession
3heUl
Protein name
3heUl
Sequence length
321 AA
Molecular weight
35747,47470 Da
Isoelectric point
4,72005
Sequence
MKALLKNLVGSVAPTLGTALGGPMGGMAANMIADVLGCKNEPKEIQKAIDNATPEQMLQLKKAETEFEIQMKELEVDVFKLEVQDTQDARKTFSKDWTARIIGIATLGGFLGYIFLITIQPPEQNSEALVNLVLGYLGGLASAIISFYFGASTTLVMTSKSGRWNWYGEGKETMQISEEGISLIKSYEGCRLEAYQDSVDVWTIGYGHTKDVKEGDKINQEEAEYMLQEEMIEYEGYINDLVEVPLEQCQFDALVCWVYNLGPTNLKKSTLLKVLNEEDYNGVPEQIKRWNKAGGVILGGLVKRREAEANLFQGKEWDKLS
Other Proteins in cluster: phalp2_6864
Total (incl. this protein): 25 Avg length: 170,5 Avg pI: 8,71
Protein ID Length (AA) pI
3heUl 321 4,72005
3GbX5 308 5,18402
8CecW 304 4,82463
8EVgS 296 5,79857
A0A0S2SYD0 144 9,51587
A0A223W0U3 149 9,72778
B5WZU3 144 9,56506
A0A127KNA7 144 9,51587
A0A481UVG0 144 9,68897
A0A481UW27 144 9,68897
A0A481UWU0 144 9,68897
A0A481UX69 144 9,68897
A0A481UX75 144 9,68897
A0A481UX79 144 9,68897
A0A481UXI5 144 9,68897
A0A481UXP5 144 9,68897
A0A481UXP8 144 9,68897
A0A481UXW1 144 9,68897
A0A481UY94 144 9,68897
A0A481UZ39 144 9,68897
A0A6J5NGG1 147 7,77748
A0A9E7TXD9 144 9,21771
A0AAU8KT00 144 9,21771
A0AAX3JLF3 146 6,60869
Similar Clusters

No similar clusters were found for representative 3heUl.

Domains

Domains [InterPro]
Unannotated
Unannotated
GH24
Representative sequence (used for alignment): 3heUl (321 AA)
Member sequence: A0A481UYU3 (144 AA)
1 321 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00959

Taxonomy

  Name Taxonomy ID Lineage
Phage Pseudomonas phage vB_Pae_BR161a
[NCBI] 		2563501 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MK511013 [NCBI]
CDS location
range 34473 -> 34907
strand +
CDS
ATGCGTACTTCCCAACGAGGCATAGACCTCATCAAATCGTCCGAGGGCCTGCGCTTGTCCGCCTATCAGGACTCGGTGGGTGTCTGGACCATCGGCTATGGCACTACGCGGGGCGTTACCCGCTACATGACGATCACCGTTGAGCAGGCCGAGCGGATGTTGGCCAATGACATTCAGCGCTTCGAGCCTGAGCTGGACAAGCTGGTGAAAGTGCCGCTGAACCAGAATCAGTGGGATGCCCTGATGAGCTTCGTCTACAACCTGGGATCGGCCAATCTTGCGTCGTCCACGCTGCTCAAGCTACTGAACAAGGGTGACTACCGGGGTGCGGCGGACCAGTTCCCGCGCTGGGTGAATGCGGGCGGCAAGCGCCTGGAAGGACTGGTCAAGCGTCGCGCGGCGGAACGGGCGCTGTTCCTGGAGCCGCTGTCGTGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0030430 host cell cytoplasm cellular component None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)
GO:0044659 viral release from host cell by cytolysis biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

PDB ID
A0A481UVG0
Method SMR
Resolution –
Chain position –
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
PDB ID
A0A481UW27
Method SMR
Resolution –
Chain position –
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
PDB ID
A0A481UWU0
Method SMR
Resolution –
Chain position –
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
PDB ID
A0A481UX69
Method SMR
Resolution –
Chain position –
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
PDB ID
A0A481UX75
Method SMR
Resolution –
Chain position –
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50

Showing first 5 of 13 structures.

The structures below correspond to the cluster representative (3heUl) rather than this protein.
PDB ID
3heUl
Method AlphaFoldv2
Resolution 82.30
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50