Protein

Protein accession
A0A3T0IDD9 [UniProt]
Representative
7lwdD
Source
UniProt (cluster: phalp2_24821)
Protein name
N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MKFVSRSDLGWGASPAAYANPKSGIVVHYNGPATGLSKSASHSKCVTYWKNTRSYHVNSNGWADIGYSFGVCPHGYVFEGRGLNKTQAAQPGGNTTYYSVTFMIGGSEKPGDDHLQAWRDVRDWLFSKGVSKSIKCHSDFVSTSCPGDYLRKLVRDGTLLGGKGDTSPGSGSGGSGGTTPPPFPLPDGWYFGPKEGPYYSVSGYYSHREDLKRWQQRMRDRGWVGIGTPDGLYGPKTEKVARQFQAEKGLIVDGLIGKQTWDAAWTAPIT
Physico‐chemical
properties
protein length:270 AA
molecular weight:29350,4 Da
isoelectric point:9,29
hydropathy:-0,60
Representative Protein Details
Accession
7lwdD
Protein name
7lwdD
Sequence length
356 AA
Molecular weight
37842,13650 Da
Isoelectric point
9,97250
Sequence
MRLERRSSFGWGPSGGGYANPRNGLVVHYDGSNQGLAGRSHSACRAYWINTRKFHVNTRDWSDIGYSWGVCPHNYVLEGRGLNRAQAAQPGGNTTWYSVTFMCGPNERPTDGQITAFRQLRAYLMGRGVAGAVSYHGRFIPTSCPGAILRGMVTSGDLINGSAGGSTPARPRPLGRQHASGTLVGGPANAAVVPYGSPVLKRGAVAANVAAAQDAIVRAYGAESADCRIEVDGHFGTATERAVTYANRKLKTKHGGVWNRGTHQGLRAVLGGPMVAWHVDEDVPVPSLVKGDTGERVRNLQRLLMRAGYDLPRYGADGDFGEETRAAVLALNRASGTTHGGVYGLGTAYALLLALR
Other Proteins in cluster: phalp2_24821
Total (incl. this protein): 3 Avg length: 305,7 Avg pI: 9,48
Protein ID Length (AA) pI
7lwdD 356 9,97250
A0A0R8VCQ3 291 9,17432
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_36432
11r0n
 207 35,0% 248 4.568E-36
2 phalp2_26920
4uKrS
 7 29,3% 364 2.024E-33
3 phalp2_784
240oa
 2 27,0% 347 5.497E-27
4 phalp2_37752
4kTIO
 51 31,0% 229 1.053E-22
5 phalp2_13951
8FOsh
 28 29,6% 256 1.617E-20
6 phalp2_30759
3icm
 1 27,0% 310 1.482E-14
7 phalp2_36077
6wXXD
 2 25,9% 420 4.706E-13
8 phalp2_36521
1qwup
 277 24,4% 294 5.797E-09
9 phalp2_19675
4Bope
 30 26,8% 235 1.579E-05

Domains

Domains [InterPro]
Unannotated
Unannotated
PG_1
Representative sequence (used for alignment): 7lwdD (356 AA)
Member sequence: A0A3T0IDD9 (270 AA)
1 356 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01471

Taxonomy

  Name Taxonomy ID Lineage
Phage Thermobifida phage P318
[NCBI] 		2500138 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MK240575 [NCBI]
CDS location
range 34016 -> 34828
strand +
CDS
TTGAAATTTGTCAGCAGAAGTGACCTAGGGTGGGGTGCCAGCCCCGCCGCTTACGCTAACCCCAAGTCCGGTATCGTCGTCCACTACAACGGCCCAGCTACCGGCCTAAGTAAATCAGCTTCCCACAGCAAATGTGTCACCTACTGGAAGAACACCCGCTCCTACCACGTCAACAGCAATGGTTGGGCGGACATCGGATATTCTTTTGGAGTTTGTCCCCACGGGTATGTTTTCGAGGGCCGAGGCCTCAATAAGACCCAGGCCGCTCAACCGGGTGGTAACACCACCTATTACAGTGTGACTTTCATGATCGGTGGTAGTGAGAAGCCCGGTGACGACCATCTTCAGGCGTGGCGAGACGTCCGCGACTGGCTTTTCTCCAAGGGAGTCAGCAAGAGCATTAAGTGCCACAGCGATTTCGTTTCCACCTCTTGCCCGGGCGATTATCTACGCAAGCTAGTCCGTGACGGCACTCTCCTCGGCGGAAAGGGGGACACTAGCCCCGGTAGCGGGTCCGGTGGTTCTGGGGGTACGACACCGCCCCCGTTCCCGCTCCCCGATGGGTGGTATTTCGGTCCCAAGGAAGGACCCTACTATTCGGTTTCTGGCTACTATTCCCACCGTGAGGATCTCAAACGTTGGCAGCAGCGGATGAGAGATCGGGGTTGGGTTGGCATCGGCACTCCGGATGGTCTTTATGGTCCCAAGACTGAGAAGGTTGCCCGCCAATTCCAGGCCGAAAAAGGTCTTATCGTCGACGGCCTGATCGGGAAACAGACGTGGGATGCGGCCTGGACAGCGCCGATCACATGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008270 zinc ion binding molecular function None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7lwdD) rather than this protein.
PDB ID
7lwdD
Method AlphaFoldv2
Resolution 79.85
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50