Protein

Protein accession
A0A3Q8I2F5 [UniProt]
Representative
2NqNa
Source
UniProt (cluster: phalp2_6932)
Protein name
Peptidase M23 domain-containing protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 97% (predicted by ML model)
Protein sequence
MTGVVWPVLPREKVRIDAGFLDPNYPSFRKSLGLSPDEHPGVDINIHGTSGNQDFGWPVVSIGEGVVVHVGSHRVWGKIVLIHHPTFKKLLGLDHEVYSQYAHLHQVCVSDGDYVYPGYPVGSIGNGDPLKPFLAHLHFEVRKVGPDVLPPDAWPKTRDKILKYYLDPVEFLNKYYKPATISAPSATIFYDGTIINVDGTVLVNFSNPKRVFVRKV
Physico‐chemical
properties
protein length:216 AA
molecular weight:24106,3 Da
isoelectric point:7,88
hydropathy:-0,14
Representative Protein Details
Accession
2NqNa
Protein name
2NqNa
Sequence length
130 AA
Molecular weight
14343,22840 Da
Isoelectric point
5,65778
Sequence
MRLIWPFPEPDRVRVDAGFLDPAYPEWRRRMGLPPDEHPGADLNLRGTSGDGDLGYPVVAVAEGRVVHARAHRVWGQIILLEHDLPGLGKFWTQYAHLLFAVVREGDWVMAGEPVGSIGKGDPLLACSSP
Other Proteins in cluster: phalp2_6932
Total (incl. this protein): 4 Avg length: 191,5 Avg pI: 7,88
Protein ID Length (AA) pI
2NqNa 130 5,65778
A0A3G8F516 210 9,00129
A0A411CVX5 210 9,00129
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_32931
3R3GB
 42 58,0% 131 1.626E-45
2 phalp2_34915
4pbkX
 159 31,5% 92 1.221E-04
3 phalp2_24104
8fsA2
 7 32,5% 83 4.192E-04
4 phalp2_7394
4DA7Z
 2 31,4% 89 5.704E-04

Domains

Domains [InterPro]
PET_M23
Representative sequence (used for alignment): 2NqNa (130 AA)
Member sequence: A0A3Q8I2F5 (216 AA)
1 130 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01551

Taxonomy

  Name Taxonomy ID Lineage
Phage Thermus phage phiLo
[NCBI] 		2301536 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MH673673 [NCBI]
CDS location
range 74359 -> 75009
strand +
CDS
ATGACTGGAGTAGTATGGCCCGTTCTTCCAAGGGAGAAGGTGAGGATTGACGCAGGCTTCCTGGACCCCAACTATCCTTCCTTTAGGAAGTCTTTGGGTCTAAGCCCTGATGAGCATCCTGGGGTGGATATAAACATACATGGAACCTCTGGAAACCAAGACTTTGGGTGGCCTGTGGTTTCCATTGGCGAGGGGGTTGTGGTCCACGTGGGAAGCCACAGAGTTTGGGGTAAGATTGTTCTCATCCACCACCCCACTTTCAAGAAGCTTCTGGGCTTGGACCACGAGGTCTATAGCCAGTACGCTCACCTCCACCAGGTGTGCGTGTCTGATGGGGACTACGTCTACCCCGGATACCCCGTGGGCTCTATTGGGAACGGGGACCCGCTCAAGCCCTTCCTTGCCCATCTGCACTTTGAGGTAAGGAAGGTGGGTCCTGATGTTCTTCCTCCCGATGCCTGGCCTAAGACCAGGGACAAGATACTAAAGTACTACTTGGACCCAGTTGAATTCCTCAACAAGTACTACAAGCCTGCAACTATCTCAGCCCCATCTGCTACCATTTTCTATGATGGAACCATAATAAATGTGGATGGAACAGTCCTAGTGAACTTCTCTAACCCTAAGAGGGTTTTTGTTCGTAAGGTTTAG

Gene Ontology

Description Category Evidence (source)
GO:0004222 metalloendopeptidase activity molecular function None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (2NqNa) rather than this protein.
PDB ID
2NqNa
Method AlphaFoldv2
Resolution 91.56
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50