Protein

Protein accession
A0A3G3LYQ8 [UniProt]
Representative
5IpUw
Source
UniProt (cluster: phalp2_36681)
Protein name
Lysin A
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MATPENFIKALKSHMGVKYTFGGKTPESGLDCSGLITYSLKQVGIDFPNGSTNQIVACTPISVEQALKTPGALLWFQGHDAISLGDGKTIEAVTTPKNGVGSYPHGGRFIKAGLIPGIDYESKKDEPMGKMVSPFAGRVTAQWRGYKNHAGMDIAPPKPGQVGLPVYAVFGGTVVRVARGVKAGNRKSTWAPGRTGNGVLVRNPDGEGNGYNHVNPVVKAGQKVKAGDLIGYNDRSGNQTGPHLHLELWADWRNSYSDYDPRRAFTKFGVVPGSNPVTSGTSGDKPSVGKPSTSKPSAKVPEPSAKVKGYLKKMGLPPTANGVKAYQKQHNLRPDGVWGSITQDKYNWVIKLQKALNLMKRSAGVQKVVVDGYQGNGTNRLKNDILKRNNWTNNNLVANLKAVKAWK
Physico‐chemical
properties
protein length:407 AA
molecular weight:43727,3 Da
isoelectric point:9,97
hydropathy:-0,53
Representative Protein Details
Accession
5IpUw
Protein name
5IpUw
Sequence length
471 AA
Molecular weight
51936,46310 Da
Isoelectric point
9,78483
Sequence
MAWYPKALKKPISHNYTRTVTAKDCVILHTAASNGDSLQGWFSNPSAQASSHFYVRKTGIVEQMVDTAYMSWANVQGNPRSVTIETEGLGSEPWTAKQVQAIVALCQWACKQHGIPVRQMASSVVTEKGIGWHRLGCDGNYPSTPSILKGRSQRGGGEDWTGAAGYGRACPGDDRIKQMPAIIKAVGGKEDKVTKRPHMVSPFQGWLSARWHGYLNHAGMDIATPVPGQVGLPVYAAFAGTVKKAVTWSKHGNSLSTWAPGRTGNGVLIENPDGEGQGYNHMRPIVKVGQKVVQGQVIGYNDTSGHQTGPHLHFECWADADNPYSDYDPQRCFTKYGVKVGSAPVSVVGSKTPAKRPSSKYLYAKLRVDGVKGPTTITAWQKLLKRYGYYKRTTDGTWGHYTALAMQHWLRKKGTYTKAYLLDGTWGKASVKALQTYLKKTKRLDSKKWKTDGIEGRETVKAEQRHLNAWR
Other Proteins in cluster: phalp2_36681
Total (incl. this protein): 3 Avg length: 450,3 Avg pI: 9,87
Protein ID Length (AA) pI
5IpUw 471 9,78483
5Fvdl 473 9,84821
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_9321
7w6Qi
 8 44,2% 330 4.178E-71
2 phalp2_30741
7uklG
 2 38,6% 326 2.033E-47

Domains

Domains [InterPro]
Ami2
PET_M23
Unannotated
Representative sequence (used for alignment): 5IpUw (471 AA)
Member sequence: A0A3G3LYQ8 (407 AA)
1 471 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510, PF01551

Taxonomy

  Name Taxonomy ID Lineage
Phage Brevibacterium phage Cantare
[NCBI] 		2338395 Cantarevirus > Cantarevirus cantare
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MK016493 [NCBI]
CDS location
range 36914 -> 38137
strand +
CDS
ATGGCAACCCCAGAAAACTTCATCAAGGCATTGAAAAGTCATATGGGCGTGAAGTACACCTTTGGTGGAAAAACCCCTGAAAGTGGTCTGGATTGTTCTGGTCTGATCACTTACTCACTGAAGCAAGTGGGTATCGACTTCCCGAACGGTTCAACGAACCAGATTGTCGCATGTACCCCGATCAGCGTAGAGCAAGCGCTGAAGACCCCGGGTGCACTTCTGTGGTTCCAAGGCCACGATGCAATTTCGTTGGGTGACGGGAAAACCATCGAAGCGGTCACTACGCCGAAAAACGGTGTAGGTAGCTATCCGCATGGTGGACGCTTTATCAAGGCCGGTTTGATCCCCGGCATCGACTACGAATCCAAGAAGGATGAACCTATGGGGAAGATGGTAAGCCCGTTCGCGGGACGCGTCACCGCTCAGTGGCGCGGGTACAAGAACCACGCTGGAATGGACATCGCGCCACCTAAGCCGGGTCAGGTGGGTCTTCCGGTCTACGCCGTCTTCGGTGGCACTGTGGTGCGCGTAGCACGCGGTGTAAAGGCTGGAAACCGCAAGTCCACGTGGGCACCGGGTCGTACCGGCAACGGCGTGCTTGTCCGTAACCCTGATGGTGAAGGTAACGGCTACAACCACGTCAATCCTGTCGTGAAGGCCGGTCAGAAGGTCAAGGCCGGTGACCTGATTGGTTACAACGACCGCAGTGGCAACCAGACCGGCCCACATTTGCATCTCGAACTGTGGGCAGATTGGCGCAACTCGTACAGCGACTACGATCCACGTCGTGCCTTCACGAAGTTCGGTGTCGTACCCGGCTCGAATCCGGTAACTTCCGGTACCAGCGGTGACAAGCCTTCCGTGGGCAAGCCATCCACCAGCAAGCCGTCTGCAAAGGTTCCAGAACCTTCGGCTAAGGTCAAGGGCTACCTGAAGAAGATGGGTCTTCCCCCGACCGCCAACGGCGTGAAGGCGTACCAGAAACAGCACAACCTTCGACCTGATGGCGTATGGGGATCGATCACTCAGGACAAGTACAACTGGGTGATCAAACTTCAGAAGGCATTGAACCTGATGAAGCGTTCCGCAGGTGTCCAGAAGGTCGTCGTAGACGGCTATCAGGGCAACGGCACAAACCGCCTGAAGAACGACATCCTGAAGCGCAACAACTGGACGAACAACAACTTGGTGGCCAACCTGAAGGCCGTCAAGGCATGGAAGTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0004222 metalloendopeptidase activity molecular function None (UniProt)
GO:0008234 cysteine-type peptidase activity molecular function None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (5IpUw) rather than this protein.
PDB ID
5IpUw
Method AlphaFoldv2
Resolution 87.49
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50