Protein

Protein accession
A0A3G3BY37 [UniProt]
Representative
bpom
Source
UniProt (cluster: phalp2_6407)
Protein name
N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MALKDKYVDNIVYDLTTSSRSRAFEKMTGGKPTAQVSHDTGNPGSTARGNANWFKSESKPSSSAHSFIDDKEIRLILPLDEKAWHIQRQVRIDERIWGGAANDIALGHELCYGGSINFAAAYDRWVWFHVYCAKQFGIPLSRIEGHFKLDPQRRTDPVNALSQNGKTWNQFLADVKRYFDAWEGDATPSQAGPSGRKEHTIQSGDTLWSIATANQMSVDELQKLNPGVVAINLQPGQKLLLNEARSSGSAPATIPQVPNRPPLPTGVYSRRQHGDRSLNAVRQIQTFSNAINFNVGTVDGRYGPRTEDAIRRFQSMYAALTVDGVYGPNTRQFMIRHFNTLN
Physico‐chemical
properties
protein length:342 AA
molecular weight:38148,2 Da
isoelectric point:9,35
hydropathy:-0,58
Representative Protein Details
Accession
bpom
Protein name
bpom
Sequence length
198 AA
Molecular weight
21913,49390 Da
Isoelectric point
6,90005
Sequence
MQLITKYILSGTKRRSGLKLNGVKFIVAHDTGNPGSTALQNANYYTSTPNEAEVSAHAFVDDTGVIEVVPDSEKAWHVRYTETIDNILFGGDANDYALGIELCYGGKIDNIAAYRNYVEYIASKCIKFGLKSNNIAGHFQLDPARRKDPITALNTIGKTWDQFKQDVQFAIDKSNPQPVKDDKSEKIKQAIALLQSVL
Other Proteins in cluster: phalp2_6407
Total (incl. this protein): 66 Avg length: 247,2 Avg pI: 6,99
Protein ID Length (AA) pI
bpom 198 6,90005
13HFk 243 7,59684
15dFR 202 4,80172
1Cw3b 247 8,48831
1L6Z1 253 8,42242
1LQiN 225 8,74522
1MtKm 225 8,54620
1lih7 255 8,22096
2G5Jx 270 6,96240
2G7bi 270 6,53884
2G8p8 262 6,60494
2T05P 248 4,88209
2uogL 217 6,44176
3OPDJ 291 6,53935
3Z0i 195 6,58226
48L08 210 8,13541
49hb1 249 5,65499
4f9Tw 226 8,22244
4gSG2 225 8,73638
4l2L6 195 6,51764
4uflW 237 5,81585
5i3dC 257 9,49183
6F4K5 259 6,95245
6LUUv 251 6,31813
6Me4f 243 5,98812
6xhzl 218 5,87877
72dis 244 8,19066
74fXb 270 8,48264
757IB 282 4,98026
76rrs 246 5,25325
77kHQ 259 7,61821
7BpRZ 257 6,71134
7G8FN 172 6,63734
7KBL0 254 8,64490
7aKZd 254 5,45532
7aL3M 266 6,00677
7cDpF 259 8,76243
7cevs 257 6,65570
7gBZ5 255 6,00245
7hA1z 259 6,53082
7hFvz 259 8,97930
7odaQ 259 6,23333
7rHRd 250 8,47206
7rI14 314 8,11123
7sVo3 262 6,53241
7vAsb 256 4,56340
7vo4m 277 7,13610
7x2Fy 254 8,45292
7x2LM 279 7,58837
7xCTk 285 6,27243
7y5kc 240 4,87561
7z5Ol 242 7,70932
7zaYT 225 7,70557
80nFV 250 6,51013
81ehI 226 9,16265
87nVp 249 5,89474
881VT 186 8,53544
884p8 256 6,11038
8MSxx 271 7,61696
8MiEU 260 6,23481
8mTtl 253 6,02291
8rCP6 250 6,51013
8s7FD 254 6,11493
IIYz 164 5,93072
bm7g 246 4,66935
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_29706
1hMzx
 5 47,4% 196 9.565E-88
2 phalp2_321
6SgOZ
 68 41,9% 198 2.492E-61
3 phalp2_18561
73HNe
 82 37,1% 191 5.641E-44
4 phalp2_27786
7skBJ
 83 31,1% 183 7.565E-32
5 phalp2_25288
86peP
 187 29,8% 174 3.522E-28
6 phalp2_39055
7ordh
 68 31,3% 182 3.522E-28
7 phalp2_3939
7bfSL
 153 32,0% 187 1.229E-27
8 phalp2_27158
38a6k
 24 31,4% 178 1.229E-27
9 phalp2_5052
1q1Q3
 64 33,1% 148 6.316E-25
10 phalp2_37528
3iFdV
 13 25,8% 201 1.425E-23

Domains

Domains [InterPro]
Ami2
Representative sequence (used for alignment): bpom (198 AA)
Member sequence: A0A3G3BY37 (342 AA)
1 198 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Bacillus phage vB_BpsM-61
[NCBI] 		2419620 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MH884514 [NCBI]
CDS location
range 43132 -> 44160
strand +
CDS
ATGGCTTTAAAGGACAAGTACGTCGATAATATTGTGTATGATCTGACAACATCGTCAAGATCCAGAGCGTTCGAGAAAATGACTGGGGGTAAACCTACAGCGCAAGTGTCACATGATACCGGAAACCCTGGATCAACCGCAAGAGGTAACGCGAATTGGTTCAAGAGTGAAAGCAAACCATCATCATCAGCGCATTCATTTATCGATGACAAGGAAATCCGTTTAATTTTACCGCTAGACGAAAAGGCATGGCATATACAACGTCAAGTAAGGATCGACGAAAGGATCTGGGGCGGTGCTGCCAATGACATCGCGCTAGGTCATGAATTATGTTATGGCGGTTCCATCAATTTTGCAGCTGCATATGATCGTTGGGTATGGTTCCATGTTTATTGTGCGAAACAGTTCGGGATCCCATTGTCTCGAATTGAAGGGCATTTCAAGTTAGATCCGCAACGTCGGACGGATCCAGTCAATGCGTTAAGTCAGAATGGAAAGACATGGAATCAATTCCTGGCAGATGTTAAACGATATTTTGACGCCTGGGAAGGGGATGCAACGCCATCACAAGCCGGACCATCTGGACGAAAAGAACACACAATCCAGTCTGGTGATACATTGTGGAGCATCGCAACAGCGAATCAAATGAGTGTGGACGAGCTACAAAAACTTAATCCAGGCGTGGTGGCGATCAACCTGCAACCTGGACAAAAGCTATTATTGAATGAAGCTAGATCAAGCGGATCTGCACCGGCTACGATTCCACAAGTGCCAAACAGACCACCGTTACCAACTGGGGTTTATTCCAGACGACAACATGGGGATAGATCGCTGAATGCAGTAAGACAAATCCAAACATTCTCAAATGCGATCAATTTCAATGTCGGTACAGTTGACGGTCGATATGGACCAAGAACAGAGGACGCCATCAGACGATTCCAATCGATGTATGCAGCACTTACAGTTGACGGTGTATATGGACCGAACACACGACAATTTATGATCCGTCATTTTAATACATTAAACTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0009254 peptidoglycan turnover biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)
GO:0071555 cell wall organization biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.5.1.28 None Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00001561

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (bpom) rather than this protein.
PDB ID
bpom
Method AlphaFoldv2
Resolution 95.52
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50