Protein

Protein accession
A0A3G3BX75 [UniProt]
Representative
2LOtm
Source
UniProt (cluster: phalp2_1764)
Protein name
Putative endopeptidase Spr
Lysin probability
100%
PhaLP type
VAL
Probability: 99% (predicted by ML model)
Protein sequence
MKNAITAYRPLGVVKFITESGELVPRSTRDPDSSIDLDIINITTTRDMQSDSPTFAIELTLRKPWHRWVASNDLVIIYMSRPPETNRVVFVGLVDDCRKTTSVSGNGVSRSIKVVGRGLAKSLIRFDIGVVPEAEYGFTNTAIGWLEAAGITIAGQKPGDITKAIWDVIVKKHVNYKWGKESLFNYLSLNTKDRENITLLDTSTIMNWQGSIHALIKDVAEDPFYETFYEVNSKGKVELIVRPTPFNKADWEKLPRHHLVDNDVLDDSTGRSDTETFSIYSVGAKTLFSPHDTYKTFGAKPLWNESYADKYGNARLHVETSYMQVADSEDATGEESKATFLQMNTDIYNWNIMNNAMYNGTIVVKGSNKYRLGDRLLYDSAENGTSMEFYITSVQNTIVNYSGNFVTVLGVTRGMNPADRFKAPWGTAKEYSGLGLLPFDPEGALAAIKGDASYRIPGINADMPNGEIDMGSANSVVEMAKDILNSGINGVKVRYVFGGNDARIGSLDCSSFTQYVYKNAVNMDIGRVTGQQVFKGSDISKSQLLPGDLVFFKNTYASTHAFGVSHVGIYIGNDEFIHNSSYAGGITKNKLAEPYWVLHWLKARRVLSQTQLTGGVTGDASTGTGAGSKYVATAYGATALNLGAPDWWVPTGKTATGTRPTEGRTIAVDKTRIPLHSKVRLTCPSFPSVNGEYIAEDVGGAIKGNRIDIYFDDLPPKDARLARTRMLAFGKRDVYIQVLRRGKG
Physico‐chemical
properties
protein length:744 AA
molecular weight:81936,6 Da
isoelectric point:8,06
hydropathy:-0,30
Representative Protein Details
Accession
2LOtm
Protein name
2LOtm
Sequence length
724 AA
Molecular weight
80177,11050 Da
Isoelectric point
8,82380
Sequence
MSEMLVSRYKPQSKVTFYSEKGNLVARGTGDPKSDIDQDVVSIRTVRDMGADAPTFTINLTRRRMWHKWIGSNDLVLIELQRPPEKMATVFVGLVDDVRKQVIIGEDSVQRIVTITGRGVNKAFIKFDIGYVPEAEVVDTSIGYMEENGVTLAGSTPDKILEAVWDKIAKKHVNYKWGEKTTLFNLMDKNLKARQNIVLKDSSTLMNFQGSIWSFMKELADEPFHEVFWEINKNGRPELILRPTPFSESRWESLPYHEIEDRHVADEQIGRSDLETYSLYSVGTQTAFSTNDPFHTFGYLPLWYKPYADKYGLHRLHVDTLFAAMSSAEDTEDSGVIKSLQKDLFNWNIHNNSFYNGSIKVVGSNQYKIGNRLRYKSIEDNSNMEYYITSVSNTYVNFGSWTTELGLTRGMKVGDRFKAPYGKSEEYKGLGLVKFDPEGAKNAMMASTAMGGATGVASGDASAVIAAGQTLIGKIKYQLGGPGMDAGRGDCSQFTRWAFQKGANIDIGVPTGTQVQKGQQIQKGSEQPGDLIFFKGTYNSPHIYGVSHVGIVVGNGQMIDCGSPGVSIRSYNTSYWNSHFLMFRRVLTASAGGGGGAFGQSGLTGVPTGKSYQMTASAYGATALNLEGGPGWVPTFKTASGTRPTEGRTIAVDRRLIPLGTKVRITCPSYPQVNGVYIAEDVGGAIKQMRIDIYFDDMPPKDPHQARKRMLAFGMRKIMVEILK
Other Proteins in cluster: phalp2_1764
Total (incl. this protein): 25 Avg length: 693,4 Avg pI: 7,21
Protein ID Length (AA) pI
2LOtm 724 8,82380
2LB6N 553 5,10127
2Uv7N 837 8,55987
2YjVn 722 8,93243
2YkA0 595 5,61600
2td3d 690 5,57411
2tewj 694 6,03081
39y4A 596 5,91253
3eyth 663 5,56615
4DXlx 839 8,42790
4E5sJ 831 8,45266
4E6hO 603 6,20809
4SXth 742 5,25712
4TnKz 697 6,49001
4lBN3 721 8,26519
6S2Us 724 5,35949
6S8W4 702 8,11749
7LSJH 837 8,55948
7PnZ6 722 8,29568
7b4y5 592 7,04067
7jzTG 838 8,42790
QPF7 605 8,74876
jqe2 598 5,46788
A0AAE9G6X5 466 9,00644
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_39443
7Ktpu
 2 43,1% 477 2.849E-166
2 phalp2_37189
1QZtJ
 98 20,5% 826 9.533E-77
3 phalp2_25144
1Emml
 5 26,1% 517 3.186E-58
4 phalp2_28907
5tXTi
 21 20,7% 852 7.837E-49

Domains

Domains [InterPro]

No domain annotations available.

Taxonomy

  Name Taxonomy ID Lineage
Phage Exiguobacterium phage vB_EalM-132
[NCBI] 		2419623 Herelleviridae >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MH884511 [NCBI]
CDS location
range 60546 -> 62780
strand +
CDS
ATGAAGAACGCTATTACAGCGTACAGACCCCTAGGAGTAGTTAAATTTATAACAGAGTCAGGGGAACTGGTACCGAGGTCTACTAGAGACCCTGACTCTTCTATTGATTTAGATATAATCAATATAACTACGACTAGAGACATGCAATCTGATTCTCCTACCTTTGCCATAGAGCTAACACTCCGTAAGCCATGGCACAGATGGGTTGCATCTAATGATTTAGTTATCATTTATATGTCAAGACCTCCAGAGACTAACAGAGTAGTGTTTGTAGGTCTAGTTGATGATTGTCGCAAAACTACATCTGTATCGGGGAATGGGGTATCAAGAAGCATTAAAGTAGTTGGTAGGGGTTTGGCTAAGTCTCTTATCAGATTTGATATTGGAGTAGTACCTGAAGCAGAATATGGCTTTACCAATACTGCTATCGGGTGGCTAGAAGCCGCAGGTATTACTATTGCAGGTCAAAAGCCAGGGGATATTACAAAAGCTATATGGGATGTTATTGTCAAGAAGCATGTTAACTACAAGTGGGGCAAAGAGTCTCTATTTAATTACTTATCTCTAAACACTAAAGACAGAGAGAATATCACCCTATTAGATACAAGTACTATTATGAACTGGCAAGGGAGTATACATGCCTTAATCAAGGATGTAGCTGAAGACCCGTTCTATGAGACCTTCTATGAAGTTAATAGTAAGGGAAAGGTTGAATTGATTGTAAGACCAACACCATTCAACAAGGCAGATTGGGAGAAACTTCCTAGACATCACTTAGTAGATAACGACGTTCTGGATGACAGCACAGGACGCTCAGACACCGAAACCTTCTCTATCTACTCTGTAGGGGCTAAGACATTATTTAGTCCACATGATACCTATAAGACCTTCGGGGCTAAGCCTTTATGGAATGAAAGCTATGCAGATAAGTATGGAAACGCTCGTCTACACGTAGAGACATCTTATATGCAAGTAGCTGATTCTGAAGATGCTACAGGGGAAGAATCCAAAGCAACTTTTCTCCAGATGAATACTGACATATACAATTGGAACATAATGAACAACGCTATGTATAACGGCACAATTGTTGTTAAAGGTTCTAATAAATATCGTCTAGGAGACAGATTGCTATATGATTCAGCGGAGAATGGAACTAGTATGGAATTCTATATCACGTCAGTACAGAATACTATAGTCAACTATTCCGGTAACTTTGTTACAGTACTAGGAGTAACTAGGGGGATGAATCCTGCTGACCGATTTAAAGCCCCTTGGGGTACAGCTAAGGAATACAGTGGACTGGGACTGCTACCTTTTGACCCAGAAGGGGCATTAGCAGCTATTAAAGGGGATGCTAGCTATCGTATCCCTGGTATTAATGCTGACATGCCTAATGGAGAAATTGATATGGGTTCAGCCAACTCGGTTGTAGAAATGGCTAAAGACATACTGAACAGTGGTATCAATGGAGTTAAAGTAAGATATGTATTCGGAGGGAATGACGCTCGTATAGGTTCTCTAGATTGTTCATCATTTACTCAATATGTATACAAGAATGCGGTTAACATGGACATCGGTCGTGTAACAGGTCAACAGGTGTTCAAGGGTAGTGATATCAGTAAGTCACAATTACTACCAGGGGACTTAGTATTCTTTAAAAATACTTATGCTAGTACTCATGCTTTTGGAGTATCCCATGTAGGTATTTATATTGGTAATGATGAATTCATCCACAACTCCAGTTACGCAGGAGGTATTACCAAGAATAAGTTAGCAGAACCCTATTGGGTACTACACTGGCTTAAGGCTCGTAGAGTATTATCCCAAACTCAGTTAACGGGTGGAGTTACTGGAGATGCTAGTACAGGGACAGGAGCAGGAAGTAAGTATGTAGCTACAGCATATGGAGCCACCGCATTAAACTTAGGAGCACCTGACTGGTGGGTACCAACGGGTAAAACTGCTACAGGTACTCGTCCAACAGAAGGTAGAACGATTGCCGTAGATAAGACTAGAATACCCTTGCATAGCAAAGTTAGACTTACCTGCCCATCGTTCCCATCAGTAAATGGAGAGTACATTGCGGAAGATGTAGGTGGAGCAATTAAGGGCAATCGTATTGATATATACTTTGATGACCTTCCTCCTAAGGATGCTCGCCTAGCCAGAACAAGAATGTTAGCTTTTGGTAAGAGAGATGTATATATTCAGGTACTCAGAAGAGGGAAAGGGTGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds molecular function None (UniProt)
GO:0008234 cysteine-type peptidase activity molecular function None (UniProt)
GO:0009254 peptidoglycan turnover biological process None (UniProt)
GO:0019867 outer membrane cellular component None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.4.-.- None None N/A UniProt

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (2LOtm) rather than this protein.
PDB ID
2LOtm
Method AlphaFoldv2
Resolution 83.63
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50