Protein

Protein accession
A0A3G3BWR1 [UniProt]
Representative
foQI
Source
UniProt (cluster: phalp2_13925)
Protein name
N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MTKASDFTVTVDAGHGLNPATAGKRTPPIPELGGRVILEREFNEPTKNLLMQELRRIGFKVVDVAPELHDVPLSTRVTRSDNAKSNLHVSVHYNAFQGRWGTHGGIEVLSGSSNNSKRASADILKHLVAETGLRRRSVVDGSWLALNRMKSPLALAECGFMDNLQEALLMLEASHQRKCAVGMAKGVCDYFGVKYVSEVTPARPRQSKGDGIGTAVISVPTLNVRSGAGVNNNVVGTVSKGDHVDVYEIKNEWYRIGQGQWVSNVGNRYAVYTEKPPAPKPEPVVVHRVIVDGKQVGAFGDFANVVNAVELAHEKGFKKQVTIERV
Physico‐chemical
properties
protein length:326 AA
molecular weight:35467,0 Da
isoelectric point:9,35
hydropathy:-0,28
Representative Protein Details
Accession
foQI
Protein name
foQI
Sequence length
263 AA
Molecular weight
28949,48560 Da
Isoelectric point
6,96649
Sequence
MSKLIAIDDGHGMETPGKRTPKFEDGSFMKENEFNKRVAELLNEHLIRCGFKTVMVAPTDVDTPLAERVKTANNAKADFYISIHANAAGDGNTFNNGKGIETFYNPGSINGEKAAKIIHRHLLNGTKLVDRGVKSTSFYVLKNTKMPAVLVECGFMTNYEEALLLKSESYRAECAEELAKGICEYFGIAYVERKSEPSSSNSQENKKPIVSGEVNVVVDGKQIANGYLINNTTYVPLRAIGEAIDANVNWDQKTQTATITTKK
Other Proteins in cluster: phalp2_13925
Total (incl. this protein): 206 Avg length: 253,8 Avg pI: 7,74
Protein ID Length (AA) pI
foQI 263 6,96649
119i4 173 6,45085
11BAR 292 9,44044
13Gnd 235 8,58972
14zE2 223 5,97374
195tx 193 8,84237
1E5SP 244 9,03268
1GGbx 300 8,96570
1GUx1 235 5,32288
1GVpl 339 9,34580
1H1Ri 299 9,07626
1H2AK 301 9,37881
1H2mR 299 8,32675
1HXKM 239 5,20153
1KJES 270 5,67102
1bZ9Z 239 8,60764
1c1sj 286 6,28943
1caVr 285 8,71176
1cjLd 254 6,15847
1ecAH 306 4,88568
1f79B 244 6,73181
1hNqV 279 6,17626
1il6O 194 8,56599
1k5o0 288 7,61741
1kGon 240 8,79279
1kGsS 239 8,59887
1l33p 226 8,03781
1lFnQ 247 6,90335
1lsHP 239 8,26332
1ms1D 239 6,97877
1oD9a 252 8,80685
1ozCA 211 9,29990
1r3wx 274 8,18009
1rtli 240 8,79744
21rBU 188 8,77004
2G6WK 277 6,46512
2HTKK 278 8,21896
2ON6r 256 7,74087
2UYKK 296 9,26258
2ZNGK 272 6,49382
2b9fY 254 5,47612
2cdd0 226 8,31798
2mcLG 291 9,22744
2oK4g 241 9,21042
2t6P7 240 5,71729
35ndY 283 6,97002
3JPyP 307 5,35318
3LJmA 238 6,71811
3NAA4 268 8,90026
3NUXN 244 7,83125
3O8M2 227 8,90007
3O9Qm 262 8,97124
3ONWJ 296 8,78242
3PEVs 240 9,31177
3PHIj 240 9,06698
3SsZI 245 9,47294
3St6p 256 8,82284
3bGfE 197 6,52997
3bUJD 301 5,09501
3bWkj 266 5,49533
3eLwV 192 7,70307
3etOk 239 8,70705
3etzN 243 8,48863
3fjht 190 9,08264
3iJ1d 244 8,59236
3j6N8 238 8,09989
3jawb 238 6,46637
3nREB 239 9,10650
3nSBF 237 9,14363
3neZ9 239 7,98700
3swxV 258 9,40383
3t1EB 182 4,24141
3vzSi 281 7,54938
3xONo 246 5,43826
47Yc0 182 5,67494
4B9Gu 277 8,85875
4CIYO 235 8,08616
4CJ3f 246 8,96641
4F3eZ 254 6,97536
4HdNB 240 8,27531
4JIsu 194 9,90365
4SBVK 262 9,01089
4SFRj 296 7,03527
4SuZh 296 8,38381
4SvyA 257 8,29607
4TAG2 262 6,23850
4UA3p 290 8,62221
4Zerg 262 6,22605
4ZuMY 244 7,12866
4bZND 181 6,29824
4hBof 276 9,62038
4i2uW 242 9,32782
4jyqK 241 6,44267
4lEOp 229 8,60835
4lEzm 300 8,58953
4lGay 277 5,87837
4oUv2 266 8,90413
4tJLP 237 8,71995
4vnxe 277 8,42687
4vu78 250 9,25271
4vvj4 247 9,13390
4wJOh 212 8,90471
54AI1 181 6,37378
55X9I 198 9,35083
58ZYh 181 6,95496
592q8 181 6,37156
5HO6W 285 8,67295
5Ky1 266 5,13935
5M8tH 295 9,22738
5OPE3 291 9,17606
5PGMK 295 9,22151
5TVQs 291 9,11172
5XjKg 307 9,39209
5Xl6r 230 7,65515
5Yfxg 246 6,31853
5YzTS 291 9,17612
5dLSR 225 8,83006
5fCXz 181 6,29818
5hRW1 261 7,00026
5hU8a 264 5,17493
5hUFs 235 7,05721
5hZSD 300 5,99904
5i2GV 235 6,08168
5i4AC 235 6,14778
5i4Am 294 6,39282
5i4yX 235 6,12840
5imMn 235 6,13534
5imkC 282 5,62975
5in1i 252 7,12638
5kjs2 253 6,52861
5kkYQ 254 6,52531
5mygv 181 6,29466
5uMMG 181 6,29824
5w9y4 181 6,29824
5zdry 181 6,37270
5zfM3 181 6,50701
67Ckx 294 9,37436
67vfa 246 6,23606
6Ao1l 294 8,94913
6Sm7K 295 5,91526
6TaJU 241 9,06305
6UJIz 302 9,34213
6UNM2 302 9,16142
6ZqWr 252 6,90886
6fNLX 246 6,32137
6kjC5 249 5,68426
6nNq0 304 9,54327
6vKV9 293 9,11178
6vMJ 238 8,54253
6vMkw 252 6,03581
6vNc7 182 4,31541
6xdNC 162 7,78599
6xkXR 198 9,42104
6zBtv 181 6,15233
79Lo6 300 8,97356
79g97 300 9,01766
7Bdu0 240 4,76569
7Fya9 235 7,61156
7YhU 198 9,16471
7bddN 228 8,82438
7c9Tl 331 7,69028
7cUOT 242 7,74900
7cUSX 296 8,93450
7d2QV 298 8,12065
7egy0 267 9,37843
7hH3m 291 8,89491
7i7cH 246 8,30032
7jgMD 194 8,34719
7p2bs 239 8,94887
7sy22 282 9,51626
7u9q8 253 7,03908
7uacT 300 9,39699
7w0yX 253 5,60412
7wCNN 296 9,27379
7wEK1 278 9,45637
7wMwm 189 9,20584
7waft 274 8,83573
7wfM8 252 9,00689
81fl9 273 6,53906
85kMT 238 8,97911
86dmd 252 7,52272
8aTDc 291 9,17612
8cb5J 246 7,00088
8dP9 257 6,98406
8eyRw 297 9,18431
8m4n5 246 5,99762
8nA4G 291 6,56078
8olYT 294 9,40763
8omp6 291 9,17612
8paRS 291 9,17612
8pnsx 246 6,23225
8qe1I 246 6,31802
9VCP 305 7,62998
9Wg2 285 6,99736
CNKW 246 6,10055
RHeU 229 9,01038
Snep 316 5,03169
bhs3 242 5,50607
efDz 273 6,41607
nKor 285 5,76634
nsgM 285 5,76634
qGRQ 237 9,09689
wBNn 214 9,05022
A0A9E8MBL7 309 9,44257
A0A9E8S4I8 309 9,44257
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_30746
7yYs5
 21 46,7% 261 1.371E-84
2 phalp2_35303
72wI1
 17 48,6% 185 6.124E-65
3 phalp2_7949
zu48
 832 45,4% 187 8.334E-62
4 phalp2_9307
7sfyx
 22 40,0% 212 3.998E-61
5 phalp2_23918
1NTlO
 42 38,1% 207 5.413E-58
6 phalp2_35096
5hXo9
 22 39,7% 204 1.896E-57
7 phalp2_24413
4m1OU
 1246 36,7% 234 1.114E-55
8 phalp2_32087
63Erl
 43 36,6% 213 5.332E-55
9 phalp2_21129
DfJM
 1 42,4% 193 2.794E-52
10 phalp2_27233
3PKbz
 18 41,0% 190 5.224E-52

Domains

Domains [InterPro]
Ami3
Cu_amine_oxidN1
Representative sequence (used for alignment): foQI (263 AA)
Member sequence: A0A3G3BWR1 (326 AA)
1 263 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01520, PF07833

Taxonomy

  Name Taxonomy ID Lineage
Phage Bacillus phage vB_BpsS-36
[NCBI] 		2419622 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MH884513 [NCBI]
CDS location
range 23151 -> 24131
strand +
CDS
ATGACTAAAGCTAGTGATTTTACTGTTACTGTTGACGCTGGTCATGGTCTTAACCCAGCAACAGCTGGAAAACGTACTCCACCAATACCAGAGCTAGGTGGTAGGGTTATTCTTGAGCGTGAGTTTAATGAGCCAACTAAAAACTTACTCATGCAAGAGCTCAGACGTATTGGCTTTAAGGTGGTTGATGTTGCTCCAGAGCTTCATGATGTACCTTTAAGCACTCGTGTAACTCGCTCAGATAATGCTAAGAGTAACCTCCATGTTAGTGTACACTATAACGCTTTTCAAGGTAGGTGGGGTACTCATGGAGGAATTGAGGTGCTTTCTGGCTCAAGTAATAACTCCAAGAGAGCTAGTGCTGATATTCTTAAGCACTTGGTTGCTGAGACTGGCTTAAGAAGAAGAAGTGTAGTAGATGGCTCATGGCTGGCTCTTAACCGTATGAAGTCACCTCTTGCACTTGCTGAGTGTGGCTTTATGGATAACTTACAAGAAGCTCTTTTAATGTTGGAAGCTTCTCACCAGCGTAAGTGTGCTGTTGGTATGGCTAAGGGAGTCTGTGATTACTTTGGAGTCAAGTATGTCTCTGAGGTTACTCCAGCAAGACCAAGACAGTCTAAAGGTGATGGAATTGGTACAGCTGTGATAAGTGTACCTACTCTTAATGTACGCTCTGGAGCTGGTGTTAATAATAATGTTGTTGGTACTGTCTCTAAGGGTGACCATGTTGATGTATATGAAATTAAAAATGAGTGGTACAGAATTGGTCAAGGACAGTGGGTGAGTAATGTTGGTAACAGATACGCTGTGTACACTGAGAAGCCACCAGCTCCAAAGCCAGAGCCAGTAGTGGTCCACAGAGTAATTGTGGATGGTAAGCAAGTTGGTGCTTTTGGTGACTTTGCTAATGTTGTTAACGCTGTTGAGCTTGCTCATGAGAAAGGCTTCAAGAAGCAAGTTACTATTGAGAGAGTCTAA

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0071555 cell wall organization biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.5.1.28 None Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides. N/A UniProt

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (foQI) rather than this protein.
PDB ID
foQI
Method AlphaFoldv2
Resolution 92.68
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50