Protein

Protein accession
A0A3G3BWP3 [UniProt]
Representative
7sgWH
Source
UniProt (cluster: phalp2_12309)
Protein name
N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MAIKDLPLYKDIRGSIRRSGRYPYVGTAVKDTHVIHHSLTETGTPQAFANYHIDTNGWHGCAYHFVIQKDGTIFQVDDLDRRTYHAGNTNTRAIGTCLVGDFRKGKQKPTAAQIRALYLLNLELYKVLPNMRYTKGHQECPGYAWKNCPGDNWNYRDAISGSKVETPTQTKPITGATYEVQEDDTLWSIAQGIDGVSLDNIMDWNPKVDPNDLKIGQVINIRKPATTSTAKTTDYTIKAGDTLWAIASRLSWVEVPDLLAINKGLKADSLTVGQKIKIPAKPTTTTTAPKAPTPAPTPSYVGKRVEAKTTVRFYSKPSWDDKDVAGEVTKGLGFTITGRVTAGGAYQYKVKNSAGKVYYITTNTKFVTVK
Physico‐chemical
properties
protein length:370 AA
molecular weight:40880,9 Da
isoelectric point:9,43
hydropathy:-0,49
Representative Protein Details
Accession
7sgWH
Protein name
7sgWH
Sequence length
389 AA
Molecular weight
43297,48150 Da
Isoelectric point
7,27047
Sequence
MAHFESLAEIKDIRGKTAKKGYYSRPPLGKKRSIAIHHSLTTSGSSAAFANYHVKTLGWPRVAYHFVIRKDGTIEWNHSLDIKSYHVGNSNEEAVGICLVGDFRTQHPTKAQLRSLKKLVTELKKDLPSYKVTKGHNEYPGYAWKACPEFDYKAALKAKVSKPSGTNNEPLLQAGDTFNAVKKLQQMLLATGEKLPKYGADGDFGTETEQAVKSFQRAQNITVDGVVGPETWEHLNKAISKDKDWKNKLAVVVADVMNVRHSPDMADDAIAGRVKKDEAFTIIDKVVASNGSTELYKLKSNLYISAHEDYTELKDVPEPEPRDELVIITHEGGLNVRDRLSFDDDAVVGQVQKGEAFTIADTHEVDGTPMFELKSGLFITAHEEYVKVR
Other Proteins in cluster: phalp2_12309
Total (incl. this protein): 3 Avg length: 333,7 Avg pI: 8,61
Protein ID Length (AA) pI
7sgWH 389 7,27047
A0A0M4S688 242 9,13751
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_8070
5Z13p
 106 26,7% 288 7.891E-12

Domains

Domains [InterPro]
Ami2
PG_1
Unannotated
Unannotated
Representative sequence (used for alignment): 7sgWH (389 AA)
Member sequence: A0A3G3BWP3 (370 AA)
1 389 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01471, PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Exiguobacterium phage vB_EalM-132
[NCBI] 		2419623 Herelleviridae >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MH884511 [NCBI]
CDS location
range 83894 -> 85006
strand +
CDS
ATGGCTATTAAAGACTTACCGTTGTATAAAGATATCAGAGGTAGCATTAGAAGAAGTGGGAGATACCCTTATGTGGGCACAGCAGTAAAAGATACGCACGTTATTCACCACTCTCTTACTGAAACGGGTACTCCTCAGGCATTTGCTAACTACCACATTGATACTAATGGATGGCATGGGTGTGCCTACCACTTTGTTATCCAAAAAGACGGTACTATCTTCCAAGTAGATGACCTTGACAGACGCACATATCATGCAGGTAATACAAATACTCGTGCTATCGGTACTTGTTTAGTAGGTGACTTCCGTAAAGGTAAGCAGAAGCCTACAGCCGCTCAAATTCGTGCACTCTACTTGCTTAACTTAGAGTTGTACAAAGTGTTGCCTAACATGCGGTACACTAAAGGACACCAAGAATGTCCTGGATATGCATGGAAAAACTGTCCAGGGGATAACTGGAACTACCGAGACGCCATCTCTGGTAGCAAAGTTGAGACTCCTACACAGACAAAACCTATCACAGGTGCAACTTATGAAGTACAAGAAGATGATACTCTCTGGTCTATTGCACAGGGGATTGATGGTGTTAGCTTAGATAACATTATGGATTGGAACCCTAAAGTAGACCCTAATGACCTTAAGATTGGTCAAGTAATCAATATCCGTAAACCTGCTACTACGTCTACAGCTAAAACTACGGACTACACAATCAAGGCAGGAGATACCCTCTGGGCTATTGCAAGCCGTTTATCGTGGGTAGAGGTTCCTGACTTGTTAGCTATCAACAAGGGACTTAAAGCAGATAGTCTTACAGTGGGTCAAAAGATTAAGATTCCTGCTAAACCTACTACTACAACAACTGCACCTAAAGCACCTACCCCTGCTCCAACACCATCTTATGTAGGAAAACGAGTCGAAGCTAAGACTACTGTCCGCTTCTATTCTAAACCATCATGGGATGATAAGGATGTTGCAGGTGAAGTAACTAAGGGATTAGGTTTCACTATCACAGGTCGAGTTACTGCGGGTGGAGCATACCAGTACAAAGTTAAGAACAGTGCAGGTAAAGTGTACTACATTACTACAAATACTAAATTTGTGACAGTTAAATAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0006508 proteolysis biological process None (UniProt)
GO:0008233 peptidase activity molecular function None (UniProt)
GO:0008270 zinc ion binding molecular function None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7sgWH) rather than this protein.
PDB ID
7sgWH
Method AlphaFoldv2
Resolution 89.72
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50