Protein

Protein accession
A0A3G3BW17 [UniProt]
Representative
7mKv1
Source
UniProt (cluster: phalp2_29154)
Protein name
Sporulation-specific N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MSNQPVVVEFDAGHGGTDPGALGNGLKEKDLTLAIAKAAKKHLLDNYEGVVVKMTRESDATLSLLARTNKAISDQADSLVSIHINSAANAQAVGYEDFRHTSQSATSASGRLQSCIHDKVSPLFTKNRGKKQANYHMVREATVRPVGKKSTPSTLTECGFIVNEGDAELLKDARFLVRLGVAHAEGVALFHGLKRKVQVEKSQVIKPAAGSVKLGEVKMSQDVKAYAEPKFGTETGSVYKKGDVRHIYAIKNGWYQMFTGEWIPSNYGKNFEYEPVKKPEPPTMTPKPSEAKPVAEKARLRRVIVDGERIGSFGDYANLERNVLQALKKDFKKIEVEDV
Physico‐chemical
properties
protein length:339 AA
molecular weight:37152,9 Da
isoelectric point:9,31
hydropathy:-0,47
Representative Protein Details
Accession
7mKv1
Protein name
7mKv1
Sequence length
346 AA
Molecular weight
38215,00660 Da
Isoelectric point
9,20900
Sequence
MTKIYLDPGHGGTDPGAIGNGLLEKVLTRKIVDYAKSYLLANYDGVEVRTSRIEDETKTLSQRTADANAWGADLIVSPHINSAEAKSANGFESFVYTNPSAASISAQNILHAEILGVMKAWGISTDRGKKRANFHMVREPKIPAVLTENLFISNAFDANRLKDEAFLKAVGEAHARGAAKFLGLPAKQVSQPVPTPPKQAPHRIAQVIVLVDNLNVRTGPGTNFPSVRQANKGEIFDVFANVNDWHNVGNDYWVFGNNGRYLSLDLNALKPRLAYPGYVFEVKKPLIKNEYVGKIQEKVNQYFGKQVVKVDDYYGEKTAAWIKEYQKAHGLKADGEVGPKTWVVMF
Other Proteins in cluster: phalp2_29154
Total (incl. this protein): 17 Avg length: 312,2 Avg pI: 9,24
Protein ID Length (AA) pI
7mKv1 346 9,20900
3LlOD 329 9,18006
4EqGf 261 8,50378
4hcys 294 9,76743
72pix 341 8,82915
7BhT6 332 8,68159
7cj3q 262 9,04055
7e5hL 290 9,70322
7emqO 294 9,70947
7h3iM 294 9,70928
7l8R8 340 7,71120
7ltBQ 343 9,07117
7lulG 294 9,72178
7r0eQ 326 9,49324
7v1KM 294 9,63017
A0A482CXV9 329 9,74009
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_17753
7uM5Y
 14 25,6% 343 2.607E-42
2 phalp2_22102
65fHc
 3 27,9% 333 4.084E-35
3 phalp2_32229
7egmh
 11 24,7% 351 1.733E-30
4 phalp2_17577
6kJnH
 104 30,8% 269 2.348E-30
5 phalp2_13925
foQI
 206 29,3% 245 5.829E-30
6 phalp2_5199
40Vx7
 1 27,0% 259 2.460E-27
7 phalp2_24300
3nP7b
 4 26,1% 272 8.211E-27
8 phalp2_9571
1kahy
 4 25,2% 265 3.697E-26
9 phalp2_30305
4ukUL
 3 28,6% 286 2.695E-23
10 phalp2_34286
3lMrj
 2 22,6% 375 6.597E-23

Domains

Domains [InterPro]
Ami3
SH3_3
PG_1
Representative sequence (used for alignment): 7mKv1 (346 AA)
Member sequence: A0A3G3BW17 (339 AA)
1 346 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01471, PF01520, PF08239

Taxonomy

  Name Taxonomy ID Lineage
Phage Exiguobacterium phage vB_EalM-137
[NCBI] 		2419624 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MH884510 [NCBI]
CDS location
range 1243 -> 2262
strand +
CDS
ATGAGTAATCAACCAGTAGTAGTTGAGTTCGATGCGGGTCATGGCGGAACGGATCCAGGGGCACTCGGGAACGGACTGAAAGAGAAAGATTTGACGCTGGCCATCGCTAAGGCTGCCAAGAAACATTTGTTAGACAATTACGAGGGTGTGGTCGTGAAGATGACCCGGGAATCTGACGCGACCCTTTCGCTCCTAGCGAGAACGAACAAGGCCATCTCAGATCAGGCGGACTCACTCGTATCAATTCATATTAACAGCGCGGCGAATGCGCAGGCGGTCGGATATGAGGATTTTCGTCACACGTCACAATCGGCCACGAGCGCGAGCGGTCGACTCCAATCATGCATCCATGACAAGGTATCGCCATTGTTCACGAAAAACCGTGGTAAGAAACAAGCGAACTACCATATGGTACGGGAGGCTACGGTGCGCCCTGTAGGCAAGAAGTCGACCCCGTCGACGCTTACCGAGTGTGGATTCATCGTCAACGAAGGAGATGCTGAGCTCTTGAAAGACGCCAGGTTCCTCGTTCGCCTTGGCGTTGCGCATGCCGAAGGGGTGGCGCTTTTCCATGGATTGAAGCGTAAGGTCCAAGTCGAGAAATCGCAGGTGATCAAACCTGCAGCAGGATCGGTCAAGCTCGGTGAGGTGAAGATGTCGCAAGACGTGAAGGCCTACGCCGAGCCGAAGTTTGGCACCGAGACAGGGAGCGTCTACAAGAAGGGAGATGTCCGACACATCTATGCGATTAAGAACGGATGGTATCAAATGTTCACTGGAGAATGGATTCCATCGAACTACGGCAAGAACTTCGAATATGAGCCCGTAAAAAAGCCTGAACCTCCAACAATGACCCCGAAACCTTCGGAGGCGAAACCTGTCGCAGAAAAGGCTCGACTGCGACGCGTTATCGTGGATGGAGAACGGATCGGCTCATTCGGAGACTACGCGAATCTCGAGCGCAACGTCCTGCAAGCGTTGAAAAAAGATTTCAAGAAAATCGAAGTGGAGGACGTCTGA

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.5.1.28 None Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides. N/A UniProt

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7mKv1) rather than this protein.
PDB ID
7mKv1
Method AlphaFoldv2
Resolution 90.16
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50