Protein

Protein accession
A0A3G2KEZ6 [UniProt]
Representative
5CjNo
Source
UniProt (cluster: phalp2_36013)
Protein name
Lysin A
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MMEFYLPHNGPRTQVFGNIQPDGHPHAGDDFGYTGADGQVHPEVYAAADGVVLYAGDSRALGWPNPYFLNPDFDRTDARDDSAGNAVIIRHDDGGMTTYNHLESWNVRQDQRVKARQRIATTGSTGRSTGKHLHFEWIPYPCNFNTPTYGRVRPTFKPRGLFMYLTQKQELEVLAAARQVNLRAKYLDAPVSAVPRKSAAEYLDTAIPRKGGRTGNTTPRNTIAYQDANLDAVKAAAAARDQAVAE
Physico‐chemical
properties
protein length:246 AA
molecular weight:27190,9 Da
isoelectric point:7,88
hydropathy:-0,64
Representative Protein Details
Accession
5CjNo
Protein name
5CjNo
Sequence length
258 AA
Molecular weight
27981,59680 Da
Isoelectric point
4,62626
Sequence
VLTLVSPHDGPVTQWFGNIQPDGLPHAGQDYGYTGPDGTVYPNVYAAAPGVVVYAGDSRALGWPNPWYFNPDFDRTDARDDSAGNTVVIEHDGGHVTTYDHLESWTVERGDRVEARQIIGITGATGRATGKHLHWELITAPFNFGTATYGRVDPNPYLSGAIAPEGTIKKEDEFMGGLIDAGQANDIVEQTVERLLDRLPELLDNKVRINAVQAESIVRATTGRVVAILKGDKIDPGQADDIARASAEYVMEELEANK
Other Proteins in cluster: phalp2_36013
Total (incl. this protein): 9 Avg length: 247,8 Avg pI: 5,47
Protein ID Length (AA) pI
5CjNo 258 4,62626
2ha3d 199 5,01572
4AmpN 284 5,22648
5CjM0 280 5,13042
5Ckj3 246 4,97179
CHks 198 4,92705
fsMV 277 4,84492
A0A7M1CIC8 242 6,59943
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_33817
1joRs
 29 41,6% 168 1.055E-30
2 phalp2_2494
5Ecd6
 8 39,6% 159 1.196E-17
3 phalp2_32733
8iF6d
 6 32,7% 174 2.457E-16
4 phalp2_20028
1oELM
 3 28,6% 206 3.322E-16
5 phalp2_25537
3nGXJ
 39 31,1% 186 1.465E-12
6 phalp2_9303
7pYyV
 24 29,4% 180 3.577E-12
7 phalp2_38873
1OvVW
 15 31,2% 189 1.173E-11

Domains

Domains [InterPro]
PET_M23
Representative sequence (used for alignment): 5CjNo (258 AA)
Member sequence: A0A3G2KEZ6 (246 AA)
1 258 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01551

Taxonomy

  Name Taxonomy ID Lineage
Phage Arthrobacter phage Corgi
[NCBI] 		2419952 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MH834607 [NCBI]
CDS location
range 11850 -> 12590
strand +
CDS
GTGATGGAGTTCTACCTGCCGCACAACGGCCCCAGGACCCAGGTATTCGGGAACATCCAGCCGGACGGCCACCCCCACGCCGGGGACGATTTTGGGTACACCGGGGCGGACGGCCAGGTGCACCCCGAGGTCTACGCCGCTGCGGACGGCGTGGTGCTGTACGCCGGGGACTCCAGGGCGCTGGGCTGGCCGAACCCGTACTTCCTGAACCCGGACTTCGACCGCACGGACGCCCGGGACGATTCCGCCGGGAACGCCGTTATCATCCGGCACGACGACGGCGGCATGACCACCTACAACCACCTGGAGTCCTGGAACGTCCGCCAGGACCAGCGCGTGAAGGCCCGCCAGCGGATCGCCACCACCGGGTCCACCGGGCGGTCCACCGGCAAGCATTTGCATTTTGAGTGGATTCCCTACCCCTGCAATTTCAACACCCCGACGTATGGCCGGGTCCGGCCCACGTTCAAACCGAGAGGACTATTTATGTACCTGACACAGAAACAGGAACTGGAAGTGCTGGCAGCTGCCCGCCAGGTCAACCTGCGGGCCAAATACCTGGACGCCCCGGTGTCCGCCGTCCCCAGGAAGTCCGCTGCCGAGTACCTGGACACCGCCATTCCCCGGAAGGGCGGGCGCACCGGGAACACCACGCCCCGGAACACGATTGCGTACCAGGACGCCAACCTGGACGCCGTGAAGGCAGCGGCGGCGGCCCGGGACCAGGCGGTGGCCGAATGA

Gene Ontology

Description Category Evidence (source)
GO:0004222 metalloendopeptidase activity molecular function None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (5CjNo) rather than this protein.
PDB ID
5CjNo
Method AlphaFoldv2
Resolution 73.42
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50