Protein

Protein accession
A0A3G2KCW1 [UniProt]
Representative
82pcH
Source
UniProt (cluster: phalp2_1609)
Protein name
Lysin A
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MTKFSSPVPVGSRSTSGFMTKARPDHAGHDWAPPEPGQHVDVYAVADGTVIAAGEGVLSGHSGKIVIIDHGKLTGNGSTDHTVTNSGHLHTINVKVGQKVKAGQKIGTMGETGNATGVHLHLGVRFNGRWADPKKWLATKKIIPGKTKPVSGGSGYSKATRDWQLSMNKMFPAYANFAGDGIYGPYSEDVTRKYQSRVGLKRTGKLDAATKKSMRSMGVKV
Physico‐chemical
properties
protein length:221 AA
molecular weight:23480,5 Da
isoelectric point:10,06
hydropathy:-0,49
Representative Protein Details
Accession
82pcH
Protein name
82pcH
Sequence length
200 AA
Molecular weight
20919,57440 Da
Isoelectric point
9,93034
Sequence
MTTYSSPVPAGSRPTSGFRTKARPTHAGDDFAPPKPGQKNVPIHAVADGTVLSVGVNILAGHSGRAVLIDHGTHKDKYGSDHMKSYSGHLESYSVRAGEKVYAGQVIGIMGETGNATGIHLHLGVLCNGKFIDPSDWLGRKGITIGRTAPAKPKASTYTVKAGDTLSAIALKHGTTSAKLAKTNGISNPNLIRVGQKIKY
Other Proteins in cluster: phalp2_1609
Total (incl. this protein): 10 Avg length: 212,0 Avg pI: 9,14
Protein ID Length (AA) pI
82pcH 200 9,93034
5IsEK 172 4,89562
6RxdZ 229 5,92333
75El 206 9,99803
7cXPZ 237 10,22760
A0A3G2KD90 206 10,13225
A0A3G2KJ81 206 10,13225
A0AA50EBH6 221 9,92815
A0AA96SFM3 222 10,18041
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_30474
4WlHp
 1 29,1% 216 6.354E-22
2 phalp2_35838
4GGll
 4 36,1% 141 2.202E-21
3 phalp2_39908
1iVNq
 39 31,5% 171 5.589E-21
4 phalp2_1375
1fRbd
 2 35,7% 151 1.243E-19
5 phalp2_30590
66hsO
 9 38,8% 139 1.694E-19
6 phalp2_12
4LMlP
 4 33,8% 139 1.694E-19
7 phalp2_35274
6TFzn
 1 32,8% 140 3.148E-19
8 phalp2_24690
60yb2
 39 30,6% 137 3.148E-19
9 phalp2_20604
4H0aV
 4 35,5% 135 1.086E-18
10 phalp2_27075
2pChT
 5 37,0% 135 2.016E-18

Domains

Domains [InterPro]
PET_M23
LysM
Representative sequence (used for alignment): 82pcH (200 AA)
Member sequence: A0A3G2KCW1 (221 AA)
1 200 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01476, PF01551

Taxonomy

  Name Taxonomy ID Lineage
Phage Arthrobacter phage Adaia
[NCBI] 		2419945 Adaiavirus > Adaiavirus adaia
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MH834594 [NCBI]
CDS location
range 11599 -> 12264
strand +
CDS
ATGACTAAGTTCAGTAGCCCAGTACCGGTAGGCAGCCGGTCAACTAGCGGGTTCATGACCAAGGCCCGCCCAGACCATGCGGGCCACGATTGGGCACCGCCGGAGCCAGGGCAACACGTAGACGTTTACGCTGTAGCCGATGGAACCGTGATCGCAGCAGGCGAGGGCGTTCTCTCGGGCCACAGCGGCAAGATTGTAATCATCGACCATGGCAAGCTGACCGGCAACGGCAGCACCGACCACACCGTGACCAACTCGGGACACCTCCACACGATCAATGTCAAGGTTGGCCAGAAAGTCAAGGCAGGCCAGAAAATCGGCACCATGGGCGAAACCGGAAACGCTACCGGCGTTCACCTGCATCTTGGCGTTCGGTTCAATGGGCGTTGGGCCGATCCTAAGAAGTGGCTCGCAACCAAGAAAATCATTCCCGGCAAGACCAAGCCCGTGAGCGGTGGCAGCGGCTACAGCAAGGCAACGCGTGACTGGCAACTATCCATGAACAAGATGTTCCCTGCATACGCCAACTTCGCGGGAGACGGCATCTACGGCCCCTACAGCGAGGACGTAACGCGAAAGTACCAATCCCGCGTTGGATTGAAGCGAACCGGCAAGCTTGACGCAGCAACGAAAAAGTCTATGCGTAGCATGGGCGTAAAGGTCTAA

Gene Ontology

Description Category Evidence (source)
GO:0004222 metalloendopeptidase activity molecular function None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (82pcH) rather than this protein.
PDB ID
82pcH
Method AlphaFoldv2
Resolution 93.47
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50