Protein

Protein accession
A0A2Z4QHK0 [UniProt]
Representative
4Pwuf
Source
UniProt (cluster: phalp2_2338)
Protein name
Glycoside hydrolase family 19 catalytic domain-containing protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MFKLNRPVFFSKVRHGPFPGRLTQSQVEGMTHLLDVWETRGTHDPRHLAYILATDFHETGARMQPVREGFARSDAAARQAVNKLAAKRGPKSAVAQYAKPHPTTGHVYYGRGDVQLTWHDNYAKMGRLLGIPLAEKPDLALDPKISKRVLVEGMLLGASKAGDFTGKALEDYFNDTTDDPVNARRIVNGTDKALLIASYHDEFLEAVEAAMDAYEQPSMFPEDVENPAPAKLPPAADQTSWGGLLAVVGGLSGSIASFTEKMSGPGVLVAVGAIVVGAVLIANGRRKTLKDTGE
Physico‐chemical
properties
protein length:294 AA
molecular weight:31772,8 Da
isoelectric point:7,15
hydropathy:-0,26
Representative Protein Details
Accession
4Pwuf
Protein name
4Pwuf
Sequence length
408 AA
Molecular weight
44308,58040 Da
Isoelectric point
9,39080
Sequence
MDRAAFFTSLRARSSGVFGSSLSQGQVDGINGILEAFEQVGNGERTTLAYALATAYHETGRKMVPVREGFATTDAGARRAVNNLARRRGPGSSVARYAQPQPPHGHVYYGRGHVQLTWLDNYRRSSADAGVDLVKNPDAMLDPVISARVLILGLIDGRWNGRGHGIEHYEDQDGLPGLSEVEAIAARRTVNVQDKAALIAGYYRAFDAALVAGGMPVASSATERPATTPRAPSASGGLLSAIIAFLSALFGGDSKKRGLVPVPHDGRTIWVTPDYHVEDGIRMPVDHPRAMEIARARGLKLPTKEMVDSIYAAADVKLIAQPIPWGRENTTLPVFRKHDEMVEAQLRQRGGLIAGHKKDILRDPTPGKVRIYGWHKADGSVWQNVSEAHGAAYKDYSHGLRLVYDPEK
Other Proteins in cluster: phalp2_2338
Total (incl. this protein): 5 Avg length: 357,0 Avg pI: 8,65
Protein ID Length (AA) pI
4Pwuf 408 9,39080
A0A2Z4QFN7 294 7,93059
A0A7G7WXW0 395 9,38880
A0A7S5REJ7 394 9,40022
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_22315
aK9v
 1 34,8% 307 4.864E-38
2 phalp2_17158
2YpB3
 1 30,6% 294 3.080E-34
3 phalp2_20018
1lijW
 1 30,4% 279 5.612E-27

Domains

Domains [InterPro]
GH19
Unannotated
Representative sequence (used for alignment): 4Pwuf (408 AA)
Member sequence: A0A2Z4QHK0 (294 AA)
1 408 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00182

Taxonomy

  Name Taxonomy ID Lineage
Phage Ruegeria phage vB_RpoS-V16
[NCBI] 		2218618 Casjensviridae >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MH015258 [NCBI]
CDS location
range 20555 -> 21439
strand -
CDS
ATGTTCAAGCTGAACCGACCTGTCTTTTTCTCCAAGGTCCGCCACGGGCCGTTCCCGGGCCGTCTGACCCAGAGTCAGGTCGAGGGCATGACCCACCTCCTCGACGTGTGGGAGACACGGGGGACCCACGATCCGCGCCATCTGGCCTACATCCTCGCCACGGATTTCCACGAGACCGGCGCACGGATGCAGCCAGTCCGCGAAGGCTTCGCCCGTTCCGACGCTGCGGCTCGGCAGGCGGTGAACAAGCTGGCCGCCAAGCGCGGGCCGAAATCGGCGGTCGCCCAATATGCCAAGCCCCACCCGACCACCGGCCACGTCTACTACGGGCGCGGCGACGTGCAACTGACCTGGCACGACAACTACGCCAAGATGGGCCGTCTCTTGGGAATCCCGCTGGCCGAGAAGCCGGACCTGGCTCTCGACCCGAAAATCTCCAAGCGGGTCCTGGTCGAGGGGATGCTGCTCGGTGCGTCGAAGGCCGGAGATTTCACTGGCAAGGCGCTGGAGGACTATTTCAACGACACGACCGACGATCCGGTCAACGCGCGCCGCATCGTCAACGGGACCGACAAGGCCCTGTTGATCGCCAGCTATCACGACGAGTTCCTGGAGGCCGTAGAGGCCGCGATGGACGCCTACGAGCAGCCGTCGATGTTCCCGGAAGATGTCGAGAACCCCGCCCCCGCGAAACTGCCGCCCGCCGCCGACCAGACATCCTGGGGCGGCCTTCTGGCCGTGGTGGGCGGCTTGTCCGGCTCGATCGCCAGCTTCACCGAGAAGATGAGCGGTCCAGGCGTCCTGGTCGCTGTCGGCGCGATTGTCGTGGGGGCCGTTCTCATTGCGAACGGTCGCCGCAAAACCCTCAAAGACACTGGAGAATGA

Gene Ontology

Description Category Evidence (source)
GO:0004568 chitinase activity molecular function None (UniProt)
GO:0006032 chitin catabolic process biological process None (UniProt)
GO:0016020 membrane cellular component None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (4Pwuf) rather than this protein.
PDB ID
4Pwuf
Method AlphaFoldv2
Resolution 87.96
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50