Protein

Protein accession
A0A2Z4Q5M5 [UniProt]
Representative
6Ryq5
Source
UniProt (cluster: phalp2_19987)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MQWPNGSKTRPSITSGFGPRKAPVPGASTFHRGTDFVGFSTVRAIAAGTVEAVGTPSGWGGGGLQVWLRHGDGSLSRYMHLRSYNVRRGEHVGEGAALGIMGATGNVSGVHLHLEIVPAGASAQVDAVGYIQARLAGTAAATTSELTRQRQDWLNHSRGEKLSEDGIQGAATTAAIKRYQGFLGVTADGIWGPGTQAAHQRYYDSVMAPAPAAQGPVTYRAIQAGLNKFGYGLAVDGIWGRKSSNALADFQRKRGLTPDRIVGPKTRAALGI
Physico‐chemical
properties
protein length:272 AA
molecular weight:28487,7 Da
isoelectric point:10,29
hydropathy:-0,26
Representative Protein Details
Accession
6Ryq5
Protein name
6Ryq5
Sequence length
277 AA
Molecular weight
30354,57990 Da
Isoelectric point
9,76891
Sequence
MHLRKSARDKEKAMGALKNHSGMWLRDDAAAAINAMEDKYGIAPINSAGRTEGQQQVLINRWNQGGPANRPPYLYKPAMPAKTSPHVRDGGIAVDVRDYAKWRPRLAEFGYTWYGPGDVVHFNWTGNWAPASAAPIAVTRDRQNWLKSRGWNIVVDGIEGPATRQAYKEYQQALNARGLNAGTPDGVWGPQTQQAHERHAAEVVAAAQNAGSRPSSKHSGELTYTDIQAALNRHGYGLAVDGVWGPKSKAALADFQSRNGLTVDRLVGPATWDKLNR
Other Proteins in cluster: phalp2_19987
Total (incl. this protein): 34 Avg length: 265,7 Avg pI: 8,73
Protein ID Length (AA) pI
6Ryq5 277 9,76891
1fOVg 289 9,44373
1gMn1 231 9,11430
1hNAl 305 8,47806
1r23L 226 9,82667
2kInC 305 9,67517
3OucS 294 6,45142
3dGG3 246 9,13274
3gm48 246 8,65032
3iEN6 246 9,00025
3iETv 246 8,92212
4G2zd 303 6,52480
4ToKg 241 9,23827
4kTm7 301 9,63772
4uIFP 296 10,17036
5hZzR 246 9,21803
6GBCB 269 7,06977
7AefF 270 7,93504
7Af7F 254 9,69406
7IgKH 218 4,75483
7zQ4w 285 9,17258
7zQbf 246 8,92212
8H60E 268 7,91254
8H60F 268 8,60274
8H60K 268 7,92060
8H60O 268 7,92060
8H60S 312 9,46094
8H60U 246 8,92212
8H615 270 8,60261
8Lp2L 256 8,65212
8LtU0 246 9,09586
8LtV2 273 8,79937
8Lwc8 248 9,73790
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_37659
4kPnj
 13 47,8% 230 7.720E-89
2 phalp2_23075
4kW5M
 8 30,1% 219 2.882E-23
3 phalp2_12264
727mo
 153 27,6% 253 1.308E-17

Domains

Domains [InterPro]
Unannotated
Unannotated
PG_1
Representative sequence (used for alignment): 6Ryq5 (277 AA)
Member sequence: A0A2Z4Q5M5 (272 AA)
1 277 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01471

Taxonomy

  Name Taxonomy ID Lineage
Phage Microbacterium phage Floof
[NCBI] 		2201433 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MH271298 [NCBI]
CDS location
range 17890 -> 18708
strand +
CDS
ATGCAGTGGCCCAACGGCTCCAAGACCCGCCCCTCCATCACGAGCGGCTTCGGTCCCCGAAAGGCTCCCGTTCCGGGGGCCTCCACCTTCCACCGTGGAACCGACTTCGTCGGCTTCTCCACCGTCCGCGCCATCGCCGCGGGCACTGTCGAGGCCGTCGGTACGCCGAGCGGCTGGGGCGGTGGCGGCCTCCAGGTCTGGCTCCGCCACGGCGACGGCTCGCTGTCCCGCTACATGCATCTCCGCTCCTACAACGTCCGCCGCGGCGAGCACGTCGGCGAGGGCGCAGCGCTGGGCATCATGGGCGCGACCGGTAATGTCTCCGGCGTCCACCTCCACCTGGAGATCGTGCCCGCGGGCGCGTCGGCCCAGGTAGATGCCGTCGGCTACATCCAGGCCCGCCTGGCGGGCACGGCAGCCGCGACGACCTCCGAGCTGACCCGCCAGCGCCAGGACTGGCTCAACCACTCGCGCGGCGAGAAGCTCAGCGAGGACGGCATCCAGGGCGCAGCCACCACGGCAGCCATCAAGCGATACCAGGGCTTCCTGGGTGTCACCGCTGACGGCATCTGGGGTCCCGGCACCCAGGCCGCGCACCAGCGCTACTACGACAGCGTCATGGCCCCGGCTCCCGCTGCCCAGGGGCCGGTCACGTACCGGGCCATCCAGGCGGGCCTCAACAAGTTCGGATACGGCCTGGCCGTGGACGGCATCTGGGGCCGCAAGTCGAGCAACGCCCTCGCGGACTTCCAGCGCAAGCGCGGCCTGACCCCCGACCGCATCGTGGGTCCCAAGACCCGCGCTGCCCTGGGTATCTGA

Gene Ontology

Description Category Evidence (source)
GO:0004222 metalloendopeptidase activity molecular function None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (6Ryq5) rather than this protein.
PDB ID
6Ryq5
Method AlphaFoldv2
Resolution 84.29
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50