Protein

Protein accession
A0A2I7S0L3 [UniProt]
Representative
7S0Q8
Source
UniProt (cluster: phalp2_19784)
Protein name
Lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MNYVDIIAFEEGFRAKPYKDSLGYPTIGYGIKLANRNANIDNFECSIPEPVAKLWLEDHASKEESKLCKSGWFIDQSKDVQDILISMSYQLGINGLLKFKNMIAALSVNDMETAAKEALDSKWARSDSPNRAKRHARVLGGESIDSVYQGLI
Physico‐chemical
properties
protein length:152 AA
molecular weight:17006,2 Da
isoelectric point:5,71
hydropathy:-0,35
Representative Protein Details
Accession
7S0Q8
Protein name
7S0Q8
Sequence length
74 AA
Molecular weight
8227,31300 Da
Isoelectric point
5,17982
Sequence
MSQIIPLLNFEEGYREKPYIDTEGYPTVACGIRIGPKGASLSNYTFTVPRDVGDAWLESFVKTTISKMNTTPPL
Other Proteins in cluster: phalp2_19784
Total (incl. this protein): 16 Avg length: 153,2 Avg pI: 7,63
Protein ID Length (AA) pI
7S0Q8 74 5,17982
R9TN12 152 7,64902
A0A2I7RTX0 152 5,20460
A0A2I7S885 152 5,19420
A0A2I7S8G4 152 5,19420
A0A2R4ALG9 152 6,89516
A0A3G8F2M1 152 6,89562
A0A6H0X6Y1 153 9,09625
A0A7T3N8Q3 180 9,11049
A0A7T3NA43 180 9,21281
A0A7T3NAQ6 180 9,21281
A0AAE8YHG7 155 9,40879
A0AAE8Z3M9 155 9,38333
A0AAE9P3S4 155 9,26419
A0AAX3DD55 155 9,40698
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_22243
7dGsY
 6 53,5% 71 4.417E-25
2 phalp2_15021
74f9k
 98 44,5% 74 2.144E-20
3 phalp2_10773
3ISMN
 265 28,7% 73 1.308E-05
4 phalp2_37746
4jFtM
 29 26,4% 53 3.180E-04
5 phalp2_32125
6B6mf
 35 28,8% 52 4.376E-04

Domains

Domains [InterPro]
Unannotated
Representative sequence (used for alignment): 7S0Q8 (74 AA)
Member sequence: A0A2I7S0L3 (152 AA)
1 74 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Vibrio phage 1.265.O._10N.286.52.F6
[NCBI] 		1881274 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MG592630 [NCBI]
CDS location
range 31678 -> 32136
strand -
CDS
ATGAATTACGTTGACATTATCGCATTCGAAGAAGGCTTTCGCGCTAAACCATACAAGGATTCGCTAGGATATCCGACCATTGGTTATGGCATTAAATTGGCGAACCGTAACGCTAACATTGATAACTTTGAATGCTCAATTCCAGAACCTGTTGCTAAGTTGTGGTTAGAGGACCACGCAAGCAAAGAGGAAAGCAAGCTTTGTAAGTCTGGATGGTTTATCGACCAATCAAAAGATGTGCAAGATATTTTAATTTCGATGTCTTACCAGTTGGGCATTAACGGCTTACTGAAATTCAAAAACATGATCGCAGCTTTATCAGTTAACGACATGGAAACAGCAGCTAAAGAGGCATTGGATTCAAAGTGGGCGCGTAGTGATTCGCCTAATCGAGCAAAACGTCACGCAAGAGTATTAGGGGGTGAATCTATTGATAGTGTTTATCAGGGTCTTATTTAG

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		RuleBase:RU003788

Tertiary structure

PDB ID
upi000ca2dd10_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (7S0Q8) rather than this protein.
PDB ID
7S0Q8
Method AlphaFoldv2
Resolution 93.21
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50