Protein

Protein accession
A0A2I7RXW8 [UniProt]
Representative
79LaP
Source
UniProt (cluster: phalp2_6329)
Protein name
N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MKRVGIVVGHSVTDPGAVNANGCSEFQFNAELSYMVSVELLKHGMNPIIIWRDRAYSAMPDKVNDHDVDFSIELHCNAFNTKASGSETLFFKNSSNSHMLAMYVQEEVTDALGLHNRGVKPTTSDDRGGLMLVKTAKPHVILEPFFIDNPKDLSVGEARKVELAVAIANGCKRFTGA
Physico‐chemical
properties
protein length:177 AA
molecular weight:19381,9 Da
isoelectric point:6,15
hydropathy:-0,15
Representative Protein Details
Accession
79LaP
Protein name
79LaP
Sequence length
183 AA
Molecular weight
20802,76530 Da
Isoelectric point
6,90704
Sequence
MKNKRVILLAGHNFISPGCHTVIDKKIITEFDLVTDIVANVFKRERLMGIDLINKARNQFGDLVSEVNSLNGDYLISCHLNAYDNKSQGTEVLYSYISQRGKELARIAQDKLVKHLGLNDRGIKPTKLNERGGSILNKTKPVAILLEPFFLDDITDRAILDDYMRKTEDAILEILNYIDKQEL
Other Proteins in cluster: phalp2_6329
Total (incl. this protein): 54 Avg length: 199,3 Avg pI: 7,06
Protein ID Length (AA) pI
79LaP 183 6,90704
16TD3 261 5,16697
1DbWj 202 4,69669
1IF3H 200 7,64873
1KFnr 209 8,51751
1LA57 226 9,01805
1N8IZ 193 5,87592
1Qrmz 206 7,01032
1lpv3 189 5,32635
2GsFK 224 5,98642
2PuO3 233 5,34010
2V7YS 182 9,78548
2Va4W 182 9,65235
2aUbL 184 6,09276
35iFt 182 5,36500
3aBbl 227 8,59668
3ak8s 199 8,88389
3iRHG 179 8,81465
3swtk 180 5,30185
4Wr0C 246 5,73655
4eRy3 185 5,74406
4gIVR 219 9,31563
4iDR5 196 5,03192
4iNpB 183 9,02533
4jMXH 264 9,53250
5IWHa 218 8,58443
5JHIR 188 5,57689
5ja28 248 6,12386
5kA9S 229 9,10998
6T2Do 202 5,71621
6T2VU 200 5,73826
6T2Wj 179 5,96323
6TYBk 209 8,99155
72Lhz 181 8,47580
72Li8 184 7,74070
7JnMA 224 5,81539
7Qqkd 174 6,15824
7UW3G 192 5,61759
7YRn0 248 6,12499
7YhXS 192 7,76900
7p9Yi 183 9,15272
7qBac 180 5,85586
7wxWF 179 7,72086
7ymyJ 181 7,01657
7zJHt 180 5,45907
867o1 187 8,78957
8IFbx 173 5,75759
8LaG6 174 5,79260
8boJE 194 5,50715
8jG9V 218 8,56122
fkfe 173 9,15266
A0A0U4I901 179 8,94584
A0A411BK48 182 5,68887
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_21852
4t88M
 271 36,0% 183 4.812E-55
2 phalp2_11016
4Prl3
 67 31,1% 180 1.079E-43
3 phalp2_40411
4aXVp
 16 31,3% 166 2.050E-40
4 phalp2_21590
2ns10
 22 30,0% 180 4.320E-35
5 phalp2_39328
4t9kP
 35 24,8% 165 2.305E-32
6 phalp2_36343
kBxJ
 714 24,8% 181 8.087E-32
7 phalp2_7941
wIlS
 251 30,0% 180 1.515E-31
8 phalp2_18510
6QgEm
 6 32,7% 122 3.882E-31
9 phalp2_5086
1FA9p
 33 26,4% 185 5.313E-31
10 phalp2_34206
2TNL2
 24 30,0% 173 1.673E-29

Domains

Domains [InterPro]
Ami3
Representative sequence (used for alignment): 79LaP (183 AA)
Member sequence: A0A2I7RXW8 (177 AA)
1 183 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01520

Taxonomy

  Name Taxonomy ID Lineage
Phage Vibrio phage 1.251.O._10N.261.55.E5
[NCBI] 		1881355 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MG592618 [NCBI]
CDS location
range 35894 -> 36427
strand +
CDS
ATGAAACGAGTCGGAATAGTAGTAGGTCATAGCGTCACAGACCCAGGAGCGGTAAACGCCAACGGGTGTAGTGAGTTCCAGTTTAATGCTGAGTTGTCTTACATGGTATCTGTGGAACTATTGAAACACGGCATGAACCCTATAATTATTTGGCGTGACCGTGCGTATAGTGCGATGCCAGACAAGGTAAACGACCATGACGTCGATTTCAGTATCGAACTACACTGTAACGCATTCAACACGAAAGCGTCGGGTAGTGAGACCCTGTTTTTCAAGAACAGTAGTAATAGTCACATGCTCGCAATGTACGTGCAGGAAGAAGTAACGGACGCACTAGGGCTTCATAACCGCGGCGTGAAGCCGACAACTAGTGACGACCGAGGCGGTTTGATGTTGGTCAAGACCGCGAAACCACATGTAATCCTAGAGCCTTTTTTCATCGATAACCCTAAAGATTTATCGGTAGGTGAAGCGCGTAAGGTTGAACTAGCTGTCGCGATTGCGAACGGCTGCAAACGTTTCACAGGAGCATAA

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi000ca1e4f1_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (79LaP) rather than this protein.
PDB ID
79LaP
Method AlphaFoldv2
Resolution 94.65
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50