Protein

Protein accession
A0A2I7RTL4 [UniProt]
Representative
2nQSj
Source
UniProt (cluster: phalp2_34149)
Protein name
Lysozyme
Lysin probability
99%
PhaLP type
endolysin
Probability: 97% (predicted by ML model)
Protein sequence
MNVLKVGLGSLYTTILLLLAIGFNPSVDYRNNVVPTPATPQETIAPVKVEVTIDDVSVTSDVVIESDNDAKLRTMANENSKQLPTDISGYIPELNMWCPHDSIEGGNDTVGYGHKFTNKEVRRGSVLIGEDEFPITECFTDASINLLFEQDWEEANASRIKWIGDDHPDEVNSVVTEMAYQMGLPTLQQFKKFKKAIEDGDYQRAADEMLDSKWAKQDSPERAEHLSKIVRSLAA
Physico‐chemical
properties
protein length:235 AA
molecular weight:26193,1 Da
isoelectric point:4,56
hydropathy:-0,39
Representative Protein Details
Accession
2nQSj
Protein name
2nQSj
Sequence length
254 AA
Molecular weight
28258,74730 Da
Isoelectric point
9,06801
Sequence
MASRSGVERIKADEGRNPRGHLVQGILHIGIGSNLETDNARERLLMAGVHPRDLDSVMKVNGKVLTPEQVDALFDLDLRQAEVDAGNSFLNFSTVPQSMKDVLVNMSFQLGKTRLNQFKKLRQAVEGEDWAKAADEMLASKWAKKDAKTRAKRLVKEVRKIQMTPIPSPISRSTLARVRSAEKEFQQQLFNQRADALSSVFSREFVIDSLANALRKQKSTEQVAEGETPTPTPPDSPQPEPTTETEIVNNEKAA
Other Proteins in cluster: phalp2_34149
Total (incl. this protein): 3 Avg length: 241,3 Avg pI: 6,06
Protein ID Length (AA) pI
2nQSj 254 9,06801
A0A2I7RY31 235 4,55811
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_34058
8tc8y
 2 37,1% 164 1.844E-26
2 phalp2_11886
2cyBF
 52 34,1% 161 1.846E-12

Domains

Domains [InterPro]
Unannotated
Representative sequence (used for alignment): 2nQSj (254 AA)
Member sequence: A0A2I7RTL4 (235 AA)
1 254 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Vibrio phage 1.235.O._10N.261.52.B2
[NCBI] 		1881352 Zobellviridae >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MG592599 [NCBI]
CDS location
range 38497 -> 39204
strand -
CDS
ATGAACGTACTAAAAGTTGGGTTGGGTAGCTTATACACAACCATACTTCTCTTACTAGCGATTGGATTCAATCCTAGCGTTGATTACAGAAACAATGTAGTACCAACACCGGCAACACCACAGGAGACCATTGCTCCTGTCAAGGTTGAGGTTACTATTGATGATGTGTCCGTCACATCTGATGTTGTTATCGAATCAGATAACGACGCTAAGCTGCGAACTATGGCTAATGAGAATAGTAAACAGCTTCCTACAGACATCTCAGGTTACATTCCTGAGCTCAATATGTGGTGTCCTCACGACTCCATTGAGGGTGGTAACGATACTGTAGGGTATGGACACAAGTTCACTAACAAAGAAGTTAGGCGAGGTAGCGTCCTGATTGGGGAAGATGAGTTCCCTATTACGGAATGTTTCACTGACGCCAGTATCAACCTGTTATTTGAACAGGACTGGGAGGAAGCAAACGCCTCCCGTATTAAGTGGATAGGTGATGATCACCCTGATGAAGTTAACTCGGTAGTCACTGAGATGGCATATCAGATGGGGCTACCTACCTTGCAACAGTTTAAAAAGTTTAAGAAAGCTATTGAAGATGGTGATTATCAGCGTGCTGCTGATGAGATGCTTGACAGTAAATGGGCTAAACAAGATAGTCCTGAACGAGCTGAACACCTGAGTAAGATAGTTCGCAGCCTTGCTGCCTAG

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		RuleBase:RU003788

Tertiary structure

PDB ID
upi000ca1e708_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (2nQSj) rather than this protein.
PDB ID
2nQSj
Method AlphaFoldv2
Resolution 82.62
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50