Protein

Protein accession
A0A2H4PP40 [UniProt]
Representative
8698a
Source
UniProt (cluster: phalp2_5261)
Protein name
Cell wall-associated hydrolase
Lysin probability
100%
PhaLP type
VAL
Probability: 99% (predicted by ML model)
Protein sequence
MGFNMLDNLRWFYGRVEDVNDPDQNGRVAVRIYGVHTEDTTLLPTELLPWGKMLMPASNASSAGLGWSPTGITVGSDVMGFALDEAYQNIRIAWVWPAATPTDGSDTNPLALGQVVQSIERQKYNAVENVPVKIEDEPQPDPQPPVDGYDPEKWMTVARGELGVKEYSGKFNNNPRILEYHKTTSLGASEDEVSWCASFVGWVLIQAGYTSTRSALARSYLQWGSPLSEPRYGAVVVFRRGNNPTFGHVAFVQKFDANYVWCIGGNQSDSVKVSRFSRSSVLGYRWPGPATTASAAPAQQNGKWSEPIPDRTPKVQETPPPSGRVQDIDNTGEVSVPSAGGSRYPYNNVMASRAGHIMEVDDTPGGERLHWMHSSGSYKQMLPDGDVVNKSVKDHYDLTMFDKRYYVGGDHNLTIGGTEVQRKKGEVYHLHSSNYSNVVAGTALMKFSQLAEIQAQNVLRLICEMLEVSNTLKVPKILASEIVCDKLSVAQTIEGNIKYAEGAGRAASRAGATPVTTTGPGPIDIKPELEDNGGNFGGKGA
Physico‐chemical
properties
protein length:541 AA
molecular weight:58979,3 Da
isoelectric point:5,58
hydropathy:-0,44
Representative Protein Details
Accession
8698a
Protein name
8698a
Sequence length
478 AA
Molecular weight
52330,83780 Da
Isoelectric point
5,83437
Sequence
MQQPDWLDWAWRELGVQEVEGKGDNPRIVEMFKAVGHQAITDDEVAWCAAFLGACLERSGRPSTHSLMARSYLTWGQPEPAARYGAVAVLSRGANPALGHVGYVLGETEGQVFLLGGNQSNSVSVAAFEKSRVLGYRWPDDEAAGDARLSDLRKIDLAESASTDTAQISEENGALENMLIASDAQFVRALDHVLLMEGGFSDDPYDPGGPTNKGITLSVFAKWVGEPITSSTRNRLVARLKRIPDAMVREIYRTRYWQPADCTRMPPALALMHFDTAVNHGVGRAIRILQQAVGADIDGEIGPQTRARTAAHPAAATLIAYAEIRREHYRSLKHFWRFGKGWMRRVDHTLLQSGTLMAQAASAAEEAVTIEHRVDVEATNRKGDTDMTTESIEPQDTAKWWGESLTIWGVIVTALSTVLPVVGPLFGLEITAEMVRQLGGQLTEIIQALGGVIGTLLTIYGRVRATQPITRRLVAVKL
Other Proteins in cluster: phalp2_5261
Total (incl. this protein): 186 Avg length: 478,2 Avg pI: 6,80
Protein ID Length (AA) pI
8698a 478 5,83437
107YL 518 10,59791
11Iw3 433 7,76736
11JDu 436 8,25513
11JGH 445 8,32327
11JcR 433 7,21664
11f0c 449 9,28752
11geL 470 7,10689
11lkh 435 8,40714
13iUT 468 8,96899
14THJ 458 6,12636
168xm 437 5,22989
1YeW1 437 5,74230
1YfMS 446 8,77216
1ljXm 436 5,41149
1pBBy 472 8,80369
1pDaB 434 6,46358
1rnlc 447 9,00483
1rnqU 439 5,29867
1rpwV 430 6,42453
1zT0B 440 6,38003
2UygK 440 5,27911
2ZWjD 445 9,35889
2dGv 457 8,10485
2e00 431 9,72185
2ecf 435 6,37884
2jzDl 443 9,82893
2mFYJ 438 6,73897
2oNnl 444 8,32147
2szLV 437 5,86882
2w865 431 8,71737
35EvF 433 7,78438
3KIc 411 9,86097
3NcvM 431 9,67169
3ZpX9 434 7,76343
3iNTS 427 8,69119
3iOJe 438 5,54734
3iP4e 437 5,47481
3iPl5 427 8,88060
4CaTI 428 9,21687
4Cc0A 434 8,95854
4Cc7r 434 6,34001
4CcaF 442 7,76724
4CyQl 438 9,23382
4KQcl 426 9,33233
4Ksi1 424 6,32120
4Ku6q 435 9,00696
4Kurx 459 10,09712
4MlHm 447 9,41234
4OGvq 430 9,49505
4VpoD 430 6,42289
4YHTI 476 8,98581
4YHhs 436 5,91406
4lFPi 431 6,14807
4uDKW 457 9,72694
5EqXp 451 9,94310
5JoAL 445 9,35767
5jc05 424 9,41356
5k3cB 436 6,80649
6BYH7 435 9,09193
6PFs0 370 8,56161
6PV0r 446 6,43113
6Pm3a 445 8,86738
6Q2S4 445 9,28972
6R37a 450 8,64716
6UgMv 439 5,36324
6UgXG 437 5,54649
6UhgU 439 5,41985
6Vmhd 432 9,59446
6Vmke 394 9,32672
6VmwK 423 8,78454
6WW17 430 9,53328
71JD6 455 9,47242
71M7I 437 9,49131
71Os5 437 5,12633
72Lyu 430 9,91564
72rxY 444 8,32327
74e9 436 5,41479
750D9 438 5,61395
7BQmw 437 5,86882
7C1Ia 435 5,11911
7cekw 442 9,50298
7cvRD 457 9,75982
7dhnf 438 6,03365
7dqTO 437 6,13466
7lrao 456 9,37868
7scZh 434 8,69506
7wguB 437 5,76452
99vZ 441 9,50053
9adJ 445 9,43670
f5qn 431 9,59214
lXjy 446 7,75229
nAXV 431 9,44541
yccZ 433 8,46272
ycjO 483 7,14258
A0A2D0Z2J5 238 6,53151
A0A7D3QPY5 186 6,29443
A0A0C5PS57 541 5,67534
A0A193GY51 541 5,58468
A0A1B0Z112 541 5,58468
A0A1X9I8Z0 541 5,50062
A0A248A8D1 541 5,58468
A0A2D0YXI3 238 6,53151
A0A2D0Z1R1 238 6,97076
A0A2H5BND8 536 5,70598
A0A2H5BPL3 536 5,69842
A0A2H5BPM7 537 5,58468
A0A2K9VAB1 536 5,70598
A0A2P0QGU6 537 5,58468
A0A2Z5HJI1 537 5,58468
A0A2Z5HLC9 541 5,58468
A0A2Z5HMS1 537 5,58468
A0A385IH79 238 6,53151
A0A385II87 238 6,53151
A0A385IPC9 537 5,50062
A0A385ITH6 541 5,58468
A0A3B8DK19 541 5,50062
A0A3G1RPN6 541 5,50062
A0A411BCL6 541 5,58468
A0A482N043 536 5,61913
A0A5B9N7K5 536 5,70126
A0A5C0CB31 541 5,58826
A0A5C0CCM9 541 5,58468
A0A5C0CDX9 541 5,58468
A0A5Q2F6Y8 536 5,61913
A0A678PBH4 541 5,50454
A0A6G6XQM1 541 5,58468
A0A6G8RLG5 541 5,58468
A0A6G8RLZ3 541 5,58468
A0A6G8RMW8 541 5,58468
A0A6G8RNT7 541 5,67534
A0A6G8RP87 541 5,58468
A0A6G8RPU7 541 5,58468
A0A6G8RQE4 541 5,58468
A0A6G9L8Q7 541 5,58468
A0A6G9L9G6 541 5,58468
A0A6G9L9V6 541 5,58468
A0A6G9L9X0 541 5,58468
A0A7D3UCZ7 537 5,58468
A0A7G3M724 537 5,50062
A0A7I8N043 541 5,67534
A0A7I8N399 541 5,58468
A0A7I8N3X1 541 5,67534
A0A7I8N470 541 5,49772
A0A7L8G412 541 5,58468
A0A7R8MNK1 536 5,70598
A0A7R8R7P6 536 5,70598
A0A7R8R7Z4 536 5,70598
A0A7T3N8H5 541 5,58468
A0A7T3N8R3 541 5,50062
A0A7T3N9H4 541 5,50062
A0A7T3TJZ1 541 5,50062
A0A7T7Z8D6 541 5,50454
A0A7T8EM95 537 5,58468
A0A7T8EMW1 541 5,58468
A0A7T8IUR7 541 5,58468
A0A8E4JCI0 537 5,58468
E1XT85 541 5,50062
G8GDI7 541 5,67534
G9IIE0 541 5,58468
I7B238 463 5,79442
K4I4A9 537 5,50062
S4TPF6 541 5,50062
S4TUZ7 541 5,50062
S6CLP5 536 5,70598
U5PYQ7 537 5,50062
U5PZ04 537 5,50062
W8JPI5 541 5,50062
X4YDL4 537 5,50454
A0A249Y074 541 5,50459
A0A976RW98 541 5,50062
A0A9E7IFU8 536 5,70598
A0A9E7IGJ0 536 5,70598
A0A9E8G9K7 537 5,50062
A0AA96H3K6 537 5,58468
A0AAE9HH10 537 5,58468
A0AAE9KSY2 536 5,70598
A0AAE9ZEG0 541 5,58468
A0AAE9ZH36 541 5,50062
A0AAU8GH67 541 5,58468
A0AAU8GHF4 541 5,58468
A0AAU8GHS7 541 5,58468
A0AAU8GK70 541 5,67534
A0AAX4GFB6 536 5,70126
G3M0Z8 537 5,58468
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_11378
3KGn
 35 48,7% 314 2.848E-127
2 phalp2_21668
35UtK
 2 41,0% 295 3.520E-94
3 phalp2_4482
3hajG
 2 30,5% 363 4.647E-66
4 phalp2_2910
IsDr
 1 31,2% 352 1.008E-64
5 phalp2_5885
5GD6E
 1 28,0% 375 3.022E-50

Domains

Domains [InterPro]
Unannotated
GH108
Unannotated
Disordered region
Representative sequence (used for alignment): 8698a (478 AA)
Member sequence: A0A2H4PP40 (541 AA)
1 478 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF05838

Taxonomy

  Name Taxonomy ID Lineage
Phage Escherichia phage FEC14
[NCBI] 		2053671 Ackermannviridae > Kuttervirus > Kuttervirus FEC14
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MG383452 [NCBI]
CDS location
range 48053 -> 49678
strand +
CDS
ATGGGTTTCAATATGTTAGACAACTTGCGTTGGTTTTACGGGCGCGTTGAAGACGTGAATGATCCCGATCAAAACGGGCGCGTCGCAGTACGCATCTATGGGGTACACACGGAGGATACCACTCTCCTGCCTACCGAATTATTGCCTTGGGGTAAAATGCTTATGCCAGCATCTAACGCCTCCTCGGCAGGTTTAGGCTGGTCTCCGACGGGTATCACTGTCGGCTCTGACGTTATGGGGTTTGCTTTGGATGAAGCATATCAGAACATCCGTATTGCATGGGTATGGCCAGCAGCAACACCAACAGATGGGTCAGATACAAACCCATTGGCGCTGGGTCAGGTCGTTCAATCTATAGAAAGGCAGAAGTATAATGCCGTCGAGAATGTTCCTGTTAAGATTGAGGATGAACCACAACCGGATCCACAACCACCAGTAGACGGATATGATCCTGAGAAGTGGATGACCGTGGCTCGTGGGGAATTGGGTGTCAAAGAATATTCTGGTAAGTTCAATAACAACCCAAGGATATTGGAATATCATAAGACAACTTCCCTGGGGGCTTCAGAAGATGAAGTTAGTTGGTGCGCGTCGTTTGTCGGATGGGTTCTGATACAGGCCGGATATACATCAACACGTTCTGCTTTGGCTCGTTCATATTTACAATGGGGATCTCCTCTGTCAGAACCACGTTACGGCGCTGTTGTTGTATTCCGGCGTGGGAACAACCCAACATTTGGTCACGTCGCATTCGTTCAGAAATTTGACGCCAACTACGTCTGGTGTATCGGGGGAAACCAATCCGATTCTGTGAAGGTGAGTCGCTTCAGCCGCTCATCTGTGTTGGGTTATCGTTGGCCTGGTCCTGCTACGACAGCATCGGCGGCTCCTGCGCAACAAAATGGTAAATGGTCTGAGCCAATCCCTGATCGTACACCAAAAGTTCAGGAAACTCCGCCTCCTTCTGGCCGTGTTCAGGATATTGACAACACAGGAGAGGTATCGGTTCCTTCGGCTGGAGGGTCTCGTTATCCATACAACAATGTTATGGCTTCTCGAGCTGGGCATATTATGGAGGTCGATGACACTCCAGGCGGGGAACGTTTGCATTGGATGCACTCTTCTGGGTCTTACAAGCAAATGCTTCCTGACGGTGATGTTGTTAATAAATCAGTCAAAGATCATTATGACCTGACGATGTTCGACAAACGTTATTATGTGGGGGGTGATCATAACCTGACAATTGGTGGGACTGAAGTACAGCGCAAGAAAGGAGAAGTTTACCACTTACACTCTTCTAACTATTCCAATGTGGTCGCTGGAACAGCGTTGATGAAATTTTCCCAATTGGCTGAGATACAGGCACAGAACGTGTTGCGTCTCATCTGTGAAATGTTGGAAGTTTCCAATACTTTGAAAGTGCCTAAAATACTGGCTAGTGAAATAGTTTGTGATAAGTTGTCGGTGGCGCAGACTATTGAAGGCAACATCAAATATGCTGAAGGCGCTGGTCGCGCCGCCTCACGTGCGGGGGCAACTCCTGTAACAACTACAGGCCCAGGTCCAATTGATATAAAACCGGAGTTAGAGGATAACGGTGGCAATTTTGGTGGTAAAGGCGCATGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0016787 hydrolase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (8698a) rather than this protein.
PDB ID
8698a
Method AlphaFoldv2
Resolution 76.08
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50