Protein

Protein accession
A0A1W6JSC2 [UniProt]
Representative
PWlr
Source
UniProt (cluster: phalp2_36408)
Protein name
Morphogenesis protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 97% (predicted by ML model)
Protein sequence
MREGQKSVGSNGKQNSLFPMDVMYITQGESGDFSHSKAKAVDYIHLTKAGKRTKQAWYYAPCDMTVITKGSAGSIWASDSEVNTPTGTKRMVYMFWHDNNHGNYPVGTKRKQGEKCGQTGTAGFATGDHLHIEVMEGSAFDKSKAIHNWDAFFINDTEIVVNFNYPWKTTDDSTGSINGSCDLGGGYDGTIQINDKVNAKVRSYEPMMKAECERQGVSLNAVPGLLGIMMVESGGEGGDPMQSSESAGLPPNAIKDPARSIAQAVKHFKESLATTEQYGCDIWTAFQQYNYGIGYARWISQRGKVHTLELSEVYSRDVVAPSLGNTTGRTRPYRNEISIANGKPYMYANGGNFHYAYMCQWYTTGDGSINTCGNETGVTEEDKAKNRQKKLLDLLMCDALNGWKW
Physico‐chemical
properties
protein length:405 AA
molecular weight:44677,4 Da
isoelectric point:6,56
hydropathy:-0,61
Representative Protein Details
Accession
PWlr
Protein name
PWlr
Sequence length
274 AA
Molecular weight
30001,86630 Da
Isoelectric point
5,22927
Sequence
MKEGQKSVGSNGKQNSLFPMDVMYITQGEGDSYSHGSAKAIDYIHMTKSGQRTYQAWYYAPCDMTVIQQGSAGTMWASDSEVNTPTGTKKMVYMFWHDNNHSNYTVGMKRKQGEKCGQTGVAGVASGDHLHIEVMNGSTFDKSNAIHNWEAFFTNDTEIVNNYNYNWVTTDDSTGVNDGTCTPPSNGGNGTFQLNEKVNAKVRSYESEMRAECERQGIPDATIPLLALMMVESGGEGGDPMQSSESAGLPMNTIKDPHASIVQGVKHFKESLET
Other Proteins in cluster: phalp2_36408
Total (incl. this protein): 18 Avg length: 402,6 Avg pI: 6,09
Protein ID Length (AA) pI
PWlr 274 5,22927
A0A1B1PAN2 412 6,21457
A0A3G8F517 412 6,01387
A0A1X9SGN0 405 6,56066
M4W8D4 413 6,26391
A0A386KT13 413 5,84807
A0A7M1RPF5 409 6,01944
A0A7L7SVG5 412 6,07685
A0A1B1PAK0 412 6,07685
A0A1I9S6P5 412 6,07685
A0A223LJE1 412 6,07685
A0A223LJH8 412 6,07685
A0A514AAR3 412 6,07685
A0A7T7GT81 412 6,07685
A0A8F2EV54 409 6,22139
A0AAE9LV64 407 6,16137
A0AAE9YJD9 404 6,07861
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_8901
3adpu
 24 82,6% 276 1.795E-172
2 phalp2_11194
66qoq
 192 44,7% 199 2.398E-42
3 phalp2_39979
1KNyb
 59 32,2% 220 8.020E-26
4 phalp2_11214
6nAAQ
 38 36,5% 186 6.844E-25
5 phalp2_38032
5TEy4
 7 32,8% 189 3.301E-19

Domains

Domains [InterPro]
Unannotated
Lys_like
Representative sequence (used for alignment): PWlr (274 AA)
Member sequence: A0A1W6JSC2 (405 AA)
1 274 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF13702

Taxonomy

  Name Taxonomy ID Lineage
Phage Bacillus phage Harambe
[NCBI] 		1981931 Salasmaviridae > Harambevirus > Harambevirus harambe
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
KY821088 [NCBI]
CDS location
range 16092 -> 17309
strand +
CDS
ATGAGAGAAGGACAAAAATCTGTAGGTAGCAACGGGAAGCAAAACTCGTTGTTCCCTATGGATGTTATGTACATCACACAAGGAGAATCAGGAGACTTTTCGCATAGTAAAGCAAAAGCGGTTGACTATATCCATCTAACAAAAGCAGGTAAGAGAACAAAACAAGCATGGTATTACGCTCCTTGCGATATGACCGTCATTACGAAAGGTAGTGCAGGCAGTATATGGGCTTCTGATAGTGAAGTAAATACACCAACTGGTACAAAAAGAATGGTATACATGTTCTGGCACGATAACAATCACGGAAACTATCCAGTAGGTACAAAGCGTAAACAAGGTGAAAAATGTGGTCAAACAGGAACAGCAGGATTTGCAACGGGTGACCATCTTCACATAGAAGTTATGGAAGGAAGTGCCTTTGACAAAAGTAAGGCCATTCATAATTGGGATGCATTCTTCATAAATGATACAGAAATCGTTGTTAACTTTAATTATCCTTGGAAAACTACAGATGATAGTACAGGTTCTATTAATGGTAGTTGTGATTTAGGCGGAGGGTATGACGGAACGATTCAAATCAATGATAAAGTAAATGCTAAAGTTAGAAGTTACGAACCTATGATGAAAGCTGAATGTGAAAGACAAGGTGTTTCTTTAAATGCTGTTCCCGGCTTACTTGGTATCATGATGGTTGAATCTGGAGGTGAAGGTGGAGACCCCATGCAGTCAAGTGAATCAGCAGGTTTGCCCCCGAACGCAATTAAAGACCCTGCAAGGTCGATAGCACAAGCGGTAAAACATTTCAAAGAAAGTTTAGCAACAACAGAACAATATGGTTGCGATATATGGACGGCTTTTCAACAATACAATTATGGTATTGGATATGCTCGTTGGATTTCGCAACGTGGTAAGGTTCATACACTTGAACTATCTGAAGTCTATTCTCGTGATGTGGTTGCCCCTTCGCTTGGCAATACAACAGGTAGAACAAGACCATACAGAAATGAAATATCAATTGCGAATGGTAAACCATATATGTATGCAAATGGTGGTAACTTCCATTATGCTTATATGTGTCAATGGTATACAACAGGTGATGGAAGTATTAATACATGCGGAAATGAAACAGGTGTGACGGAAGAAGATAAAGCAAAAAACAGACAAAAGAAACTACTAGACTTGTTAATGTGTGACGCATTGAACGGGTGGAAATGGTAA

Gene Ontology

Description Category Evidence (source)
GO:0003824 catalytic activity molecular function None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi000a275884_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (PWlr) rather than this protein.
PDB ID
PWlr
Method AlphaFoldv2
Resolution 90.19
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50