Protein

Protein accession
A0A0K2FJL3 [UniProt]
Representative
3OISx
Source
UniProt (cluster: phalp2_24325)
Protein name
Putative endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MRFIPAAHHSAGSNSPVNRVVIHATCPDVGFPSASRKGRAVSTANYFASPSSGGSAHYVCDVGETVQCLSEGTIGWHAPPNPHSLGIEICADGGSHASFRVPGHAYTREQWLDPRVWPAVEKAAILCRRLCDKYNTRGSSGLILACGLRWRRLPSCVDVCVTNIMFRKGNCRLPI
Physico‐chemical
properties
protein length:175 AA
molecular weight:18898,4 Da
isoelectric point:9,17
hydropathy:-0,13
Representative Protein Details
Accession
3OISx
Protein name
3OISx
Sequence length
474 AA
Molecular weight
49858,26160 Da
Isoelectric point
6,92460
Sequence
MTIPAGTYGGATLTAAQTAVAGQVFAVAYTLPLPPAQQDRAALAALMTAWVESRFSNPPLGAGDKDSVGVMQQRLDYWAGVPDVRGDVTGATRQFLTGVQTTRHTARTQGLTGLTGWTAGDLGGWCQTVQHSGFPLRYGQEKAVSDAVYAALKGLTMASEPPITLQAAHTSGTQSVINRLVIHATCSDVAPYPHEALPGTAHSTARYFSSSSSGGSAHYVCGVEAEEHCVKDDTVAWHAPPNHDSIGIEITADGGDPSVFHHSHNYTRDQWLSPQVWPAVQRAARRTRDLCARHNVPVVQLSTADLKAGHRGITGHVNVSQAFGQTNHTDVGANFPWLEFMAEVKGAPAPKPTPTPAPKPAPTPTPAPTPKGPGLTVNGHLDSATIKALQHTLGTGVDGVISSPSAMVSELQRFLIHHGAHLTVDGYGLAQDGKAYQTVKALQHYLGTGEDGIFSVPVSGGVKALQHRLNSGRL
Other Proteins in cluster: phalp2_24325
Total (incl. this protein): 4 Avg length: 233,8 Avg pI: 7,85
Protein ID Length (AA) pI
3OISx 474 6,92460
A0A0K2FIM4 143 8,21251
A0A0K2FJ86 143 7,07454
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_39054
7o3xD
 152 26,4% 370 1.822E-13

Domains

Domains [InterPro]
Unannotated
Ami2
Unannotated
Representative sequence (used for alignment): 3OISx (474 AA)
Member sequence: A0A0K2FJL3 (175 AA)
1 474 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Propionibacterium phage PAC5
[NCBI] 		1690809 Pahexavirus >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
KR902982 [NCBI]
CDS location
range 15388 -> 15915
strand +
CDS
GTGAGGTTTATTCCTGCGGCGCATCATTCTGCCGGCTCGAATAGTCCGGTGAATAGGGTTGTGATCCATGCGACATGCCCTGATGTGGGGTTTCCGTCTGCCTCACGTAAGGGGCGGGCGGTGTCTACAGCAAACTATTTTGCTTCCCCATCGTCGGGGGGTTCGGCGCATTATGTGTGTGATGTTGGGGAGACGGTGCAGTGCCTGTCAGAGGGGACTATTGGTTGGCATGCCCCGCCGAATCCGCATTCTTTGGGTATAGAGATTTGCGCGGATGGGGGTTCGCACGCCTCGTTCCGTGTGCCGGGGCATGCTTACACGAGGGAGCAGTGGCTTGATCCTCGCGTGTGGCCTGCGGTGGAGAAGGCTGCCATCCTGTGTAGACGTTTGTGTGACAAATATAATACACGAGGGAGCAGTGGCTTGATCCTCGCGTGTGGCCTGCGGTGGAGAAGGCTGCCATCCTGTGTAGACGTTTGTGTGACAAATATAATGTTCCGAAAAGGAAACTGTCGGCTGCCGATTTGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
A0A0K2FJL3
Method SMR
Resolution –
Chain position –
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
PDB ID
upi0006bdafa1_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (3OISx) rather than this protein.
PDB ID
3OISx
Method AlphaFoldv2
Resolution 86.29
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50