Protein

Protein accession
A0A0K2CMS0 [UniProt]
Representative
7A0jR
Source
UniProt (cluster: phalp2_36911)
Protein name
Lysin A
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MYQNRKEHMSFRTVYGYDWSENGWRMCNRDECDIVKLPELYLVDTAPLRKGAPLTILGAWIYWYDRNVEEIFTPVWGWSATNDVANSNHLSGTAVDICAPKYPWKRYTMTADKIAKVRQGLDLFEGTVFWGRKWGETGVGSPDEMHYQMAFREGDARNEAFAKKLKDGYLGIYKAPPPVVTPPAPALDPIARHQKFLKEATERELLVYIAEQLGPGHPDWASKGKTVRDKVFGL
Physico‐chemical
properties
protein length:234 AA
molecular weight:26792,2 Da
isoelectric point:7,69
hydropathy:-0,53
Representative Protein Details
Accession
7A0jR
Protein name
7A0jR
Sequence length
341 AA
Molecular weight
37694,04660 Da
Isoelectric point
5,62515
Sequence
MSFRTIYGLDWSENGWRMCNRDECVVANVLPFTNTAPIRKGVAATILNAWTLWYHYNVEELTSPVWGWSATNDVASSNHLSGTALDFNAPKYPWGLRTMPAARIAKIREGLRLFEGTVYWGADWGRADEMHYQIGFREGDARLTNFAAKLDNGYLGIYAAAPAPAPEPIVIANEIDAEAKVAAAWIGTRLHDGERPCKEGVGRYADFTGGSIYWHPELNVVDGIARAIAVPTLVYGTWAGQMWEQGTLGYPVGRHTVIEGVGDVQRFQGGVICRRYGHAGQVVHGAILERWEVLGGALGQYGFPLTDEYPEGDLGRAQRFERGILRWHPTGVVGSLDEIVQ
Other Proteins in cluster: phalp2_36911
Total (incl. this protein): 93 Avg length: 287,4 Avg pI: 7,22
Protein ID Length (AA) pI
7A0jR 341 5,62515
10Jja 315 6,08117
1Yfjj 244 9,54437
1b1YH 257 9,19301
1rqgk 329 5,70575
1rs9r 242 9,50762
2VGS7 341 6,07844
2fZNe 260 9,14002
3YSB2 328 5,63345
3YZjD 305 6,76074
3Zcb8 331 5,35124
4ErDV 320 5,15691
4LKcy 266 5,85040
5Bl5c 289 5,70706
5EXkh 267 6,32097
6UYd0 259 7,06159
7AFY8 342 8,76540
7AIP5 317 5,28338
7BsFp 318 5,42974
7BtBM 321 5,75361
7ByCi 262 8,90278
7PX57 325 5,33925
7PZlu 314 5,28554
7ZuL7 259 6,52054
7b1Gx 315 5,44389
7cEg1 316 5,28906
7cOV0 189 5,24308
7cpLz 258 9,11591
7e0IT 318 5,45247
7gGd3 314 4,83287
7jySg 317 5,52096
7k0IY 244 9,06414
7lCcs 250 9,92911
7lN7q 302 9,74905
7lN9l 280 9,75750
7mBsn 333 6,80058
7myCl 260 9,50659
7o2Ph 244 9,01141
7o3eY 247 9,24001
7qJDS 315 5,41291
7qJKv 316 5,15765
7qg1d 300 5,18590
7r4gI 321 5,20665
7ukkj 239 9,84537
7uko5 246 8,90387
7v2m9 303 5,15492
7vb4l 252 9,38597
7vnkR 246 9,40022
7x2be 260 9,11888
7xju6 244 8,90387
7xuD7 246 9,26586
7yfSQ 260 9,22306
7yyuO 231 9,46488
7zfxZ 340 6,37372
81Obn 263 8,46600
83LLE 259 7,76758
8HMRT 341 8,97679
8HwAd 327 5,83301
8HwAe 317 5,54876
8HwAg 321 6,10715
8HwAl 315 5,56484
8LXFG 315 5,01595
8MK7I 314 5,41462
8MK90 316 5,50613
8MQqw 317 5,35318
8MZrV 316 5,25467
8hAoL 263 8,46600
8hPz3 259 7,76758
8jT21 259 7,76758
8pPL1 310 6,06736
8sR4Y 263 8,46600
8xUiY 328 5,63345
A0A2U8UIZ5 341 5,62515
A0A514CX19 342 8,76540
A0A6N0A576 343 8,97672
A0A1W6DXS2 227 5,78191
A0A0K1LIU2 221 6,90732
A0A1U9WRZ3 341 8,97679
A0A160DD15 343 8,97659
A0A0N7CEF9 260 5,85290
G9FGV0 244 9,44992
A0A385D1L3 343 8,62202
A0A7T7GTD3 343 9,18392
A0A482J4S3 234 6,53321
A0A2P1N2A3 226 6,90732
A0A4Y6EFD6 260 9,15885
A0A660GBR1 281 5,09717
A0A649VZU7 226 6,90732
A0A8A1VEN3 215 6,09805
A0A8A1VIS5 238 8,78332
A0A9E7LI85 348 9,07220
A0AA96QYH6 260 9,13635
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_7160
2QyXm
 1 26,9% 342 3.616E-28
2 phalp2_4160
1P0RP
 2 25,4% 216 2.868E-16

Domains

Domains [InterPro]
PET_M15
LGFP
Representative sequence (used for alignment): 7A0jR (341 AA)
Member sequence: A0A0K2CMS0 (234 AA)
1 341 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF08310, PF13539

Taxonomy

  Name Taxonomy ID Lineage
Phage Mycobacterium phage Chadwick
[NCBI] 		1698366 Benedictvirus > Benedictvirus chadwick
Host Mycobacterium smegmatis str. MC2 155
[NCBI] 		246196 Actinobacteria > Actinobacteria > Corynebacteriales > Mycobacteriaceae > Mycobacterium >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
KT246486 [NCBI]
CDS location
range 4240 -> 4944
strand +
CDS
TTGTATCAAAATCGAAAGGAACACATGAGTTTTCGCACCGTGTACGGGTATGACTGGTCCGAGAACGGTTGGCGCATGTGCAACCGCGACGAGTGCGACATCGTCAAGCTCCCTGAGCTATACCTGGTCGATACCGCCCCGCTCCGTAAAGGCGCTCCCCTGACCATCCTCGGCGCGTGGATCTACTGGTATGACCGCAACGTCGAGGAGATCTTCACCCCGGTCTGGGGATGGTCGGCAACGAACGACGTCGCCAACTCAAATCACTTGTCTGGCACCGCAGTTGACATCTGCGCGCCTAAGTACCCGTGGAAGCGGTACACGATGACAGCGGACAAGATCGCAAAGGTCCGTCAGGGCCTGGATCTGTTCGAGGGAACGGTGTTCTGGGGTCGAAAGTGGGGCGAGACGGGAGTCGGCTCCCCCGACGAGATGCACTACCAGATGGCATTCCGAGAGGGCGACGCCCGCAACGAGGCGTTCGCCAAGAAGCTCAAGGACGGCTACCTCGGCATCTACAAGGCACCTCCCCCCGTTGTAACTCCCCCGGCCCCGGCTCTTGATCCCATCGCAAGGCACCAGAAGTTCCTCAAGGAGGCTACCGAGCGCGAGCTCCTCGTTTACATCGCAGAGCAGCTTGGTCCCGGCCATCCGGACTGGGCCTCGAAGGGTAAGACCGTCCGAGACAAGGTGTTCGGCCTGTGA

Gene Ontology

Description Category Evidence (source)
GO:0008233 peptidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7A0jR) rather than this protein.
PDB ID
7A0jR
Method AlphaFoldv2
Resolution 91.35
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50