Protein

Protein accession
A0A0A7RTQ5 [UniProt]
Representative
7wMn3
Source
UniProt (cluster: phalp2_11358)
Protein name
Putative N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MDIKKTNLKFRGILSNRSMTKYIIYHHAEHGNCSVYDIHNWHLNNSWSGIGYNFFVRKDGSIWEGRPIDAMGAHAVGYNDIAVGICAEGKYAIEDMPQAQKKALIELGIYLKNKYNINHNNIIGHRDVNPTSCPGANFPLTEIKQSILKGKVPTINNSYINIDGGAYASYKCGAPGINLIIKDYSPDINRIFAWVDSDKGASWAFDLTPPNQNYTKLFKNTSKVITKRNGGYTFSKDSMYKLKVKGYNKCGQVIAENQIVLKVPKI
Physico‐chemical
properties
protein length:266 AA
molecular weight:29858,8 Da
isoelectric point:9,39
hydropathy:-0,41
Representative Protein Details
Accession
7wMn3
Protein name
7wMn3
Sequence length
267 AA
Molecular weight
29436,84860 Da
Isoelectric point
9,11939
Sequence
MSYIDDFINSVKDGAIASMKAHGVLASITIAQAILESNWGNSTLAKESKNLFGIKAIGEWRGAKKSYATYEYYNGKKTLINDFFRVYNSIAESIEDHALFLVNNSRYKQYGFFSAKDYIGQANALQEAGYATAPTYAQSLINLIKQHGLDKYDVVKANSFIKLDGGGYASYNGGAPGVNLIIREYSTDIVRVFAWVDSDKGASWAFDLVPPNSNYTVLKKNTSKVITARNGGYSFSKGANYKITVKGYNKDGQVISENQIIIKVPLE
Other Proteins in cluster: phalp2_11358
Total (incl. this protein): 16 Avg length: 259,4 Avg pI: 9,39
Protein ID Length (AA) pI
7wMn3 267 9,11939
3bUNc 263 9,31170
7B1zZ 242 8,90503
7cBZn 239 9,21003
7eiCB 266 9,59594
7qJ9b 266 9,70966
7qy6e 242 9,05608
7uM46 237 9,14370
7wMnQ 266 9,37772
8JLcM 266 9,60426
8MdQ3 266 9,50762
A0A0A7RUD5 266 9,60426
A0A0A7S0M4 266 9,50762
A0A0A7RUS8 266 9,60426
A0A0A7RVQ3 266 9,55803
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_15148
8J4ZV
 1 38,0% 205 8.817E-30
2 phalp2_29864
43LSc
 1 31,3% 188 1.192E-21
3 phalp2_33802
1gDLS
 1 28,4% 232 3.195E-18
4 phalp2_31185
7Uzlm
 1 28,0% 164 2.658E-09

Domains

Domains [InterPro]
GLUCO
Unannotated
Representative sequence (used for alignment): 7wMn3 (267 AA)
Member sequence: A0A0A7RTQ5 (266 AA)
1 267 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01832

Taxonomy

  Name Taxonomy ID Lineage
Phage Clostridium phage phiCT453B
[NCBI] 		1567013 No lineage information
Host Clostridium tetani
[NCBI] 		1513 Firmicutes > Clostridia > Clostridiales > Clostridiaceae > Clostridium >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
KM983328 [NCBI]
CDS location
range 33866 -> 34666
strand +
CDS
TTGGATATAAAGAAAACTAATTTAAAATTTAGAGGGATTTTAAGTAATAGAAGCATGACAAAATATATTATATATCATCATGCAGAACATGGTAATTGTAGCGTATATGACATACATAACTGGCATTTAAACAATAGCTGGAGTGGTATAGGATATAATTTCTTTGTAAGGAAAGATGGTTCCATATGGGAAGGTAGACCTATAGATGCTATGGGAGCACACGCAGTGGGTTATAACGATATAGCAGTTGGTATATGTGCGGAGGGCAAATATGCAATAGAAGATATGCCACAAGCACAAAAGAAAGCACTTATAGAGTTAGGTATATATCTTAAAAATAAATATAATATAAACCATAATAATATTATAGGGCATAGAGATGTTAATCCTACAAGTTGCCCTGGTGCTAACTTTCCACTTACGGAAATAAAACAATCTATATTAAAAGGAAAAGTTCCAACTATAAATAATTCCTACATTAATATAGACGGCGGAGCATATGCTTCATATAAATGCGGAGCTCCTGGAATAAACTTAATTATAAAAGATTATAGTCCAGATATTAATAGAATATTCGCTTGGGTGGATAGCGATAAAGGGGCAAGCTGGGCATTTGATTTAACACCACCAAACCAAAACTATACAAAGTTATTTAAAAACACTAGTAAGGTAATAACAAAGAGAAATGGAGGATATACTTTCAGCAAAGATTCCATGTATAAGCTAAAAGTAAAAGGATATAATAAGTGTGGACAGGTCATAGCAGAAAATCAAATAGTTCTTAAGGTGCCAAAAATATAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008270 zinc ion binding molecular function None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7wMn3) rather than this protein.
PDB ID
7wMn3
Method AlphaFoldv2
Resolution 92.35
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50