Protein

Protein accession
A0A0A1IUP1 [UniProt]
Representative
76Uj5
Source
UniProt (cluster: phalp2_8184)
Protein name
Putative baseplate hub subunit and tail lysozyme
Lysin probability
99%
PhaLP type
endolysin
Probability: 97% (predicted by ML model)
Protein sequence
MKDLPWMIEARKYLGLAEVVGPKHNPTILGWLRQLKAWWAEDETPWCGTFVAAMLRATDRFVIKHWYRALAWKEAGTILSKPAYGCLVVFNRSGGGHVGFLEGVDSRGNLMVLGGNQGNRVSVAPFDRKRVVAYVWPSRADGTPSLPYPERYQLPVLRSDGKLSTNEA
Physico‐chemical
properties
protein length:168 AA
molecular weight:18828,5 Da
isoelectric point:9,61
hydropathy:-0,23
Representative Protein Details
Accession
76Uj5
Protein name
76Uj5
Sequence length
263 AA
Molecular weight
29545,82680 Da
Isoelectric point
9,31222
Sequence
MKLIDNWKQSYKLKSVQIGALSAIFFALSLFSEHFLTLWNVIPQEVKNSIPEQWKEYVGAFVGVAMILARLKKQPELHEPQLNLTGVNTLISATVSTTNDLAWMIEAKKHLGLKENTSKTAHNPTILKWLKSLGAWWQEDETPWCGTFVAWCLKTAGIAYPKHWYRALDYVNYGSKLAKPAYGCVAIKTRSGGGHVCFVAGRDIKTGKLVCIGGNQSNMVCYALYNESDFQEFRWYGKTSRPAESRYKLPVLSGVTSTKVTEA
Other Proteins in cluster: phalp2_8184
Total (incl. this protein): 62 Avg length: 247,3 Avg pI: 9,33
Protein ID Length (AA) pI
76Uj5 263 9,31222
1aeZD 256 9,44148
1bEDw 254 9,14505
1bKHf 253 9,19379
1bKJE 254 9,05705
1bPew 256 9,44148
1bU3q 256 9,44186
1bVPP 251 9,57563
1bXR3 251 9,04790
1btsB 254 9,16620
1buZL 263 9,27740
1buwG 256 9,44148
1c49L 263 9,18392
1dEek 256 9,34600
1dF8J 256 9,44148
1iice 251 9,12274
1jL6Z 263 9,32414
1jP7C 254 9,05705
1nL7A 254 9,16620
4rf32 263 9,32414
5GQMf 263 9,31222
72XGI 192 9,36618
72p9d 256 9,34548
7322a 254 9,14505
73kXd 256 9,39145
73r2L 256 9,44148
748Du 263 9,31222
75wWc 256 9,44148
75xhm 256 9,44148
7732A 256 9,44148
773yw 256 9,44167
776XH 256 9,50053
776eg 256 9,45469
7772d 256 9,44148
77tdJ 256 9,44148
78vG8 256 9,45469
792cb 256 9,37881
79i2k 256 9,48705
79qU8 256 9,44148
7cAgP 263 9,31222
7cAiD 263 9,25175
7dyq7 198 8,90349
7eiRI 263 9,32414
7fob5 256 9,33652
7gl9x 256 9,39145
7kawv 201 9,19940
7oaLK 263 9,18405
7p5az 256 9,54282
7pzLv 251 9,19546
7r7lh 263 9,36669
7v0R0 256 9,39151
7xrbS 254 9,16620
7yBu4 256 9,36669
7ygTy 263 9,24053
82sAe 259 9,25149
82sWe 259 9,25136
82tHl 267 9,22937
A0A1L2C8R8 168 9,47771
A0A0S0NA80 168 9,51226
A0A8S5RWV7 175 9,57866
A0AAE8XG99 168 9,38887
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_27942
Cm1J
 135 44,6% 188 3.252E-62
2 phalp2_32166
6PqA1
 486 38,8% 175 2.530E-43
3 phalp2_21029
9AcO
 22 36,2% 174 1.182E-32
4 phalp2_38714
WdJZ
 70 32,7% 168 9.268E-29
5 phalp2_20540
4muWr
 288 33,7% 172 1.496E-23
6 phalp2_33920
1ZuoD
 42 33,5% 167 5.874E-22
7 phalp2_32686
8dG3n
 26 33,5% 167 8.143E-17
8 phalp2_4988
6SJtv
 21 31,7% 170 1.101E-16
9 phalp2_10979
4Rzbr
 8 27,3% 190 2.001E-07

Domains

Domains [InterPro]
Disordered region
Unannotated
Unannotated
Representative sequence (used for alignment): 76Uj5 (263 AA)
Member sequence: A0A0A1IUP1 (168 AA)
1 263 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Pseudomonas phage vB_PaeS_PAO1_Ab18
[NCBI] 		1548905 Mesyanzhinovviridae > Abidjanvirus > Pseudomonas virus Ab18
Host Pseudomonas aeruginosa
[NCBI] 		287 Proteobacteria > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas > Pseudomonas aeruginosa group

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
LN610577 [NCBI]
CDS location
range 55242 -> 55748
strand +
CDS
ATGAAAGACCTACCGTGGATGATTGAGGCCCGCAAGTACCTCGGACTGGCCGAGGTGGTTGGGCCCAAGCACAACCCGACCATCCTGGGCTGGCTGCGCCAACTGAAGGCGTGGTGGGCCGAGGACGAGACCCCGTGGTGTGGCACCTTCGTGGCCGCCATGCTCCGGGCGACAGACCGTTTCGTGATCAAGCACTGGTACCGGGCGCTGGCCTGGAAGGAAGCGGGAACAATCCTGTCGAAGCCCGCCTACGGGTGCCTCGTCGTGTTCAACCGCTCCGGTGGGGGCCACGTTGGCTTCCTCGAGGGCGTGGACAGCCGGGGCAACCTGATGGTGCTGGGCGGCAACCAGGGCAACCGCGTCTCGGTCGCTCCGTTCGACCGCAAGCGTGTGGTCGCCTACGTCTGGCCCAGCCGGGCGGACGGCACGCCTTCCCTCCCGTATCCGGAACGCTACCAGCTCCCCGTCCTTCGCAGCGATGGCAAGCTGAGCACGAACGAGGCGTGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (76Uj5) rather than this protein.
PDB ID
76Uj5
Method AlphaFoldv2
Resolution 83.24
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50