Protein

Protein accession
A0A2H4PB86 [UniProt]
Representative
8MDGi
Source
UniProt (cluster: phalp2_15152)
Protein name
Putative transglycosylase IsaA
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MKKSVFLTGLSLAVGLIIGGTSVSANTVTVQAGDTVAEIASQNGTTVQQIVNQNNLQNPNLIYVGDKIVIPGGNSTVASQTTATVQQSQQSTKSSDQGSYQPVSSTSGTLSPSEKQAVVNQMEQRTGVSASEWSSIIYRESRDQVHASNPSSTATGLFQTLVGGEGDVQSQIDNAVNLYHAQGMQAWALTN
Physico‐chemical
properties
protein length:191 AA
molecular weight:19947,7 Da
isoelectric point:4,94
hydropathy:-0,27
Representative Protein Details
Accession
8MDGi
Protein name
8MDGi
Sequence length
133 AA
Molecular weight
13893,71670 Da
Isoelectric point
4,94280
Sequence
MSQPVQSSSSSASQATQSSQSSVQATQSVSSTSQSSYTGSSVTTSNGTLADSEKQAVLSQMQSRTGVPASTWDAIITRESNWQVDAANPSSTARGLFQQLYGGTGSVQSQIDNAVKLYHNAGDSMSPWALTNY
Other Proteins in cluster: phalp2_15152
Total (incl. this protein): 7 Avg length: 151,0 Avg pI: 5,79
Protein ID Length (AA) pI
8MDGi 133 4,94280
7zOtp 133 6,52792
8LlSX 141 7,98449
A0A3S7UP64 133 4,94280
Q5ULJ3 193 4,63769
A0A2K9VCL2 133 6,52792
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_34143
2kZPk
 47 29,2% 106 5.020E-07
2 phalp2_26606
8tBUU
 34 29,8% 114 1.274E-06

Domains

Domains [InterPro]
Disordered region
Unannotated
Representative sequence (used for alignment): 8MDGi (133 AA)
Member sequence: A0A2H4PB86 (191 AA)
1 133 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Lactobacillus phage Lenus
[NCBI] 		2053682 Lenusvirus > Lenusvirus lenus
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MG252693 [NCBI]
CDS location
range 34994 -> 35569
strand +
CDS
ATGAAGAAGAGTGTTTTTTTAACAGGATTGTCATTAGCAGTTGGGCTAATTATTGGTGGAACATCCGTATCAGCTAATACGGTTACCGTGCAGGCCGGAGATACGGTTGCGGAAATTGCAAGTCAGAATGGTACCACAGTTCAACAAATTGTGAACCAAAACAATTTACAAAACCCAAACCTGATTTATGTTGGAGATAAAATCGTAATCCCAGGTGGTAATAGCACAGTCGCTAGTCAAACAACAGCGACAGTCCAACAATCGCAACAAAGTACGAAATCAAGCGATCAAGGAAGCTATCAACCAGTAAGTTCTACAAGTGGCACGCTATCACCTTCGGAAAAGCAAGCTGTTGTCAATCAAATGGAACAGCGTACTGGTGTAAGTGCATCTGAATGGTCATCTATTATTTATCGTGAATCACGAGATCAAGTCCATGCGTCAAACCCTTCAAGCACGGCTACAGGACTGTTTCAAACTCTTGTGGGTGGCGAAGGTGACGTTCAATCTCAAATTGATAATGCAGTTAACTTGTATCATGCACAAGGTATGCAAGCCTGGGCATTAACAAACTAG

Gene Ontology

No Gene Ontology terms available.

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi000ca0af94_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (8MDGi) rather than this protein.
PDB ID
8MDGi
Method AlphaFoldv2
Resolution 60.68
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50