Protein

Protein accession
A0A221SB46 [UniProt]
Representative
7xQBg
Source
UniProt (cluster: phalp2_27798)
Protein name
Hydrolase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MYKSAIAAILVASAIVVATPTSSEAATLKSKALSVAKAQKGDRYLYGAEGPNAFDCSGLSWYSYKKSGKTIKRVANDQYNASKHISASAAQPGDLVFFKYKSGGKVFHMGIVSKKGYMVHANAGGYYGKKVIEEKIAPYWGKNYRVYYGSVK
Physico‐chemical
properties
protein length:152 AA
molecular weight:16443,7 Da
isoelectric point:9,80
hydropathy:-0,25
Representative Protein Details
Accession
7xQBg
Protein name
7xQBg
Sequence length
576 AA
Molecular weight
64037,10180 Da
Isoelectric point
9,05325
Sequence
MIEVIIIKTNGDKFDISPLVEKITWSGDYKQSARKLEFSLMASSCDINVASVDIPLGSAVVFYENQKEIFRGTVFTRSKNSSENSIDYLAYDRGVYLLKNKGAYNFTDTPAEKIVNKIAEDYKLFVGNIVETKIKVTKIFMDVNLYEIIMSAYTIAAKENKKKYMCFFKQDKLYLEKKGITKLKIAFEEGVNIKSTDYSESIEDIVNKVLVVDESSNKVAEYKKDNIPLYGTFQDILQVKKGEDTKKQAEEKFKDVEKSCSLSGYGNTDCITGYGVEVKDSYTGLVGHFYIDSDKHSWKKGEYSIDLKLNFQNLMDEHEAGKDEIESEELEGGMSLNGTKVKALFTAYYPHNSKMEGGFYDCQGKRLNPSKKTCAAPKSIALGTKIQVQGTGTSRDGEVYKVNDRGGAIKIRNGVYQFDLLMSSGSECNRWGRKNGSAVLGDGSGYSPGSIGGYTATGKAADLIRVAMAKRGKRYVWGATGPNTFDCSGLTQWSHKQIGINIPRVARAQAASGKSVSKNSMKPGDLVFFKKGKNPVHHVGIFLGNGEYLHAPQTGDVVKVSKLSSRRDFYSVRRYV
Other Proteins in cluster: phalp2_27798
Total (incl. this protein): 127 Avg length: 532,2 Avg pI: 8,57
Protein ID Length (AA) pI
7xQBg 576 9,05325
1mXZ0 509 8,34996
21fT8 499 9,76040
23zWo 582 9,73719
24pTA 582 9,77923
2bT7F 470 8,34674
3BTOY 684 8,51803
3Q2OV 473 7,93872
3lZol 580 8,20272
3pzzc 583 9,62489
3qNCU 566 9,04506
3x7tf 658 9,44451
3xNsk 575 8,39148
5MdkY 810 9,12880
5QzEY 810 9,19011
5SZhi 464 7,52408
5VmwH 804 9,08664
5WVck 810 9,08348
5XBRH 465 8,13618
5oyd 575 9,43181
61KIk 590 8,66515
62QVh 811 9,10618
63hPX 802 9,15659
64HH5 477 8,74522
65Zb4 478 8,89395
66gyj 810 9,05615
6cVl6 810 9,11262
6dIsm 811 9,07085
6dwrA 506 8,77648
6i9K9 464 8,58282
6jN3N 570 8,50462
6jyZR 575 8,22341
6lLNa 580 8,37691
6og1D 468 8,41965
6oiJZ 810 9,12874
6pyG2 506 8,58102
6r2uW 810 9,05292
6sUhX 587 9,06898
6uogL 477 8,28710
74A3X 564 8,26531
74nQX 509 8,48328
74oij 509 8,48328
74ooi 509 8,48328
74pr6 509 8,48328
74q4x 495 8,73045
74siS 419 6,23736
74u0r 509 8,48328
74u63 509 8,48676
74uEE 514 8,34029
74ubm 489 8,49037
74ufn 510 8,61525
74uhC 489 8,49037
74vCD 498 8,69319
74vJs 509 8,48328
74vYP 505 8,17989
74yTR 509 8,48328
759NU 509 8,35003
759Py 558 8,29697
75UUG 509 8,59094
75Ug1 604 8,12020
75Ugp 606 8,33352
7BnJR 505 9,06092
7BvcD 563 8,89266
7BvdI 455 8,63285
7RuWv 446 5,25303
7RutU 558 7,47714
7Rv4d 506 8,72646
7Rvoq 558 7,46418
7RwIn 574 8,63646
7RwcK 498 8,86023
7Rwzp 532 8,30122
7UmlN 810 9,08671
7Z6T4 573 8,61415
7dRbq 536 8,33036
7dRdK 589 8,40843
7doxP 535 8,56077
7eav1 543 8,11491
7eaw2 506 8,55420
7eaxS 509 8,17854
7goxL 476 7,47912
7kcel 498 8,71331
7mpQz 517 8,29690
7mpT9 563 7,57041
7mpUe 506 8,49289
7mpq6 509 8,48328
7mpr2 505 8,90594
7mpsG 558 7,91132
7mpye 498 8,91935
7mpzI 589 8,64058
7mqcW 506 8,86190
7uuno 486 8,58469
7vohG 505 8,85352
7voom 558 7,57217
7vovU 509 8,48328
7vowc 507 8,58127
7x30b 558 7,57217
7x36L 498 8,95261
7x37B 506 8,74902
7x3zh 509 8,58733
7xl9a 439 8,53486
7yQdK 515 8,57438
7zAki 498 8,88917
82oLR 588 8,85720
82zYy 583 6,32313
82zmh 599 9,23369
88BFD 802 9,11262
8JA1f 447 5,25382
8JA4G 506 8,74902
8JA4T 414 8,18628
8JA4j 572 8,70060
8JA4z 526 6,68872
8JA53 542 7,14701
8JA5d 558 7,13383
8JA5e 558 7,90687
8gj4d 586 7,44082
8tf83 802 9,15659
wK6I 580 8,33069
A0A5Q2WIE6 152 9,84086
A0A6M3T9L9 152 9,78503
A0A0A0RLD4 152 9,78567
A0A1J0GVU1 161 9,80205
A0A6G8R2J0 154 10,07514
A0A6G8R3H3 154 10,07514
A0A7G4AW96 152 10,10118
A0AAE8YBR0 152 9,79824
A0AAX4QW33 575 9,60368
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_2344
4SDRd
 25 38,4% 588 4.672E-176
2 phalp2_18606
7xlzz
 28 50,4% 361 1.424E-168
3 phalp2_23526
7aLOU
 1 27,9% 583 2.049E-87
4 phalp2_22078
5KWSa
 64 29,0% 581 4.578E-82
5 phalp2_36884
7t5S8
 17 28,3% 581 2.137E-79
6 phalp2_22550
1qxeg
 1 27,6% 430 2.354E-58
7 phalp2_19342
7oxgz
 1 25,3% 647 5.344E-56
8 phalp2_17556
5VOoO
 1 23,7% 590 5.872E-52
9 phalp2_34789
3xruw
 12 18,7% 587 7.836E-38
10 phalp2_20808
5VYZD
 107 23,0% 652 1.469E-35

Domains

Domains [InterPro]

No domain annotations available.

Taxonomy

  Name Taxonomy ID Lineage
Phage Streptomyces phage Warpy
[NCBI] 		2015805 Stanwilliamsviridae > Samistivirus > Samistivirus jay2jay
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MF358541 [NCBI]
CDS location
range 97950 -> 98408
strand +
CDS
ATGTATAAGTCAGCGATAGCTGCGATATTGGTCGCCTCTGCTATTGTGGTGGCAACACCTACTAGTTCAGAGGCAGCAACATTGAAGTCAAAGGCCCTGAGTGTCGCAAAGGCACAGAAGGGTGATAGATATCTCTATGGTGCTGAGGGACCAAATGCTTTCGATTGTTCCGGCCTTTCTTGGTATTCTTACAAGAAGTCTGGCAAGACAATCAAGCGCGTAGCTAATGACCAGTACAACGCTTCTAAGCACATCAGTGCGAGCGCTGCACAGCCAGGAGACCTTGTATTTTTCAAGTACAAGTCTGGTGGTAAGGTCTTTCACATGGGCATTGTGTCCAAGAAGGGGTACATGGTCCATGCAAATGCTGGTGGATACTATGGCAAAAAGGTAATTGAGGAGAAGATTGCTCCATATTGGGGTAAGAACTATAGAGTCTACTACGGCTCTGTCAAGTAG

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008234 cysteine-type peptidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi000b8b92f6_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (7xQBg) rather than this protein.
PDB ID
7xQBg
Method AlphaFoldv2
Resolution 89.21
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50