Protein

Protein accession
W0LN01 [UniProt]
Representative
8Jrom
Source
UniProt (cluster: phalp2_24932)
Protein name
Lysin A
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MARRLFRGRAFSENGWPYVDQGSCTWVEVVPGVWLQFQNGPCLTVMVAFARDFHAHVEPLRDYDSACWTQDNTVDTSNHPGGTGMDLNWNGADQKTFRYGITKERAYPGDKARKLDELLAFYEDVIYCGGYWSIRDWMHFQMGYGTYDSKADRPTEKTLDFIRRKIRPDGFSTFNRGGSAAPDAASILARATGIPLDRARTVLPTLRDGLIQAECNTFPRIAMFLAQTCWESDQYRATEEYANGPMNEERWIYKGRTWIQLTWRSAYEGFGRWCHARGLVDDPMVFVNNPRSLADLRWAGLGAAYYWTTTVRNTRKYPTLNQASDARDVLVATQIVNGGTTHLAERTAIYNRAIALGDELLHILGEEEDFLSALNPQEQRLLFDKTLQVWGALFNKVESKSGYRNPGGTSDPANMWAVKDYVSNMDGFIHEDFVESQAKRGNMTELARVVQAARGRGADTSPGFVARAQRVLAEIERDDPEILQRFLAAERGAA
Physico‐chemical
properties
protein length:494 AA
molecular weight:55906,0 Da
isoelectric point:6,00
hydropathy:-0,49
Representative Protein Details
Accession
8Jrom
Protein name
8Jrom
Sequence length
504 AA
Molecular weight
56189,26310 Da
Isoelectric point
5,44599
Sequence
MALGGRMENGWPECDLSDCDFATVPGTPLRLPFRKGHPFIILQAFLRDLNEFIEPLMNSRGATDEGSWTDNNSVYTSNHKGASAFDYNWDDHPMGPAAPDPRAGWNGSVLIDGDQTPAVRELLSFYTYKGIQLVWWGNDWDSPKDSMHFQMGYNTVNNPAIVQEFIDKYIRPDGFSTFRRGGNAPQAPVVDAATVLAKAVGIGYEKAKTILPAVRAGLIQSECKSSPRIAMWLAQVGHESDSFEATEEYADGNEAEERWKYKGRTWIQLTWLSAYQGFGRWCFDRGLVSDPNCFVNDPRSLAELRWAGLGAAYYWTTTVRSTRKYPTLNQASDARDVLVATQIVNGGTNGLDKRQARYNRAIALGDELLQILGGDNDDMAQVPQDQWSWVLKAVSELHGAMFNRIVSQSPYRYPKNPDGSEPPGNVWQLHELIKNGDGMAHMAYVENAARGGDLTELGRVVRAARGQGAETAPWFVQRAQRVIAEIEKTNPDLLKRYIAERGVA
Other Proteins in cluster: phalp2_24932
Total (incl. this protein): 307 Avg length: 485,9 Avg pI: 5,74
Protein ID Length (AA) pI
8Jrom 504 5,44599
10vWZ 474 5,12241
11Hzg 500 6,20269
14TyW 549 5,69563
18qA9 493 4,72334
1LQ88 495 5,97630
1MmqP 495 6,10044
2RXej 507 5,04278
36wJq 460 4,87465
3Ammx 456 5,77361
3NR9o 489 4,98770
3XbhC 383 5,79317
4EoYZ 505 4,29682
4F6TU 649 6,33183
4HQT8 428 5,53074
4W2gp 485 4,28006
4eG0M 421 5,07734
4eTT3 507 4,82383
4eUpn 457 4,78007
4gQFA 490 4,76631
5BDJ6 595 4,68208
5BDio 614 4,58017
5Bkwm 472 5,00328
5Bn8P 584 5,43662
5CkQW 496 5,35380
5JEdU 367 5,13952
5hTao 560 5,90565
6Ddey 486 4,63109
6JdzZ 428 5,24154
6KOma 496 4,91608
6Syhe 522 4,82344
71OvZ 471 5,57093
728N7 401 5,35590
76Yk3 433 5,02021
76nre 481 5,47970
77wFE 471 4,78393
7AIAb 491 6,21952
7AIBF 466 5,79885
7AIUr 498 6,00074
7AIjO 440 5,60673
7AJ03 437 5,43008
7AJ5C 403 5,34476
7AJPF 489 5,86422
7AJQP 403 5,26604
7AJj4 490 6,05650
7AJoP 499 6,40208
7AK4j 464 5,83352
7AKhE 451 5,73224
7AKj6 449 6,67957
7Ar5N 509 5,27758
7Av8G 472 5,94396
7AvuT 482 6,35144
7PTDT 505 5,50960
7PUzb 464 6,09959
7PWkQ 482 6,39935
7PYYV 481 6,14761
7Q0WB 458 6,03377
7Q0zO 490 5,75645
7YhNl 450 5,16123
7ZSZ3 467 4,91290
7b5lf 425 4,73636
7hrX1 477 5,33300
7iIDt 493 6,52139
7iL6O 473 6,05508
7iLr0 482 6,19576
7iMss 437 5,70598
7j5bi 433 5,08006
7jFSg 491 5,26792
7jxKM 440 5,42019
7k4FY 451 5,19568
7lbMR 493 5,30481
7pM8D 438 4,99805
7pNsP 433 5,01913
7pO54 474 5,32157
7pRru 491 5,44412
7pSjq 474 5,40763
7pTBx 467 5,16294
7pTP1 472 4,87419
7pWnX 440 5,13054
7q53O 467 5,32601
7q5Cd 467 5,08325
7q6Pw 490 5,10604
7q6ru 490 5,15515
7qJdS 411 4,57869
7qaLm 433 5,08006
7qbBu 477 5,23614
7qbjJ 472 4,86493
7qbmX 433 5,08728
7qkJb 471 4,74994
7qlzF 440 5,06807
7qm80 489 4,97730
7qytQ 490 5,58923
7riqc 502 5,33169
7tLqC 467 5,90883
7tj5w 474 5,40467
7ubGM 484 5,12150
7uhOU 529 5,19187
7v2o5 459 5,13486
7wtRc 470 5,54705
7zQQ3 489 5,71444
7zRzp 404 5,47862
8JrlK 471 5,91435
8Jrlc 433 6,38406
8Jrle 430 5,75145
8JrmQ 473 6,24492
8JrmR 453 5,26218
8Jrmr 455 5,96624
8Jrmx 472 6,00444
8JrnO 500 6,14358
8JrnT 498 5,58616
8Jrny 491 6,65632
8JroQ 503 6,49200
8JroR 503 5,45480
8JroS 489 5,62600
8JroU 450 6,02257
8JroV 489 5,18374
8Jrok 489 6,21986
8Jron 491 6,17478
8Jrp7 490 5,71990
8Jrpc 436 5,41138
8Jrpd 432 5,52779
8Jrph 426 5,44139
8Jrpm 404 5,40086
8Jrpn 403 5,33317
8Jrpv 403 5,27281
8KNGg 509 5,31367
8LJ20 565 5,14480
8LWtl 498 6,54139
8M2Ek 501 5,88991
8M5rM 450 6,07986
8M84n 473 6,19218
8M8r7 494 5,99546
8MHmh 450 6,11874
8MLe6 403 5,33868
8MMjr 504 5,94675
8MPm7 450 5,86836
8MVFA 501 5,74230
8MZDN 489 5,32208
8MZYD 434 6,22690
8MkXv 502 5,86814
8ivDz 542 5,00464
8qGC4 421 5,15265
8rSOt 543 4,92450
8tDpv 549 5,22699
8v6px 560 5,61242
OWa1 506 4,81690
R8Q3 567 4,96281
R8Qw 440 5,97244
A0A3Q9R8T6 504 5,44599
A0A6B9LKF0 491 6,21952
A0A3S9UD29 498 6,00074
A0A482JIL1 490 6,05650
A0A6B9LKJ5 499 6,40208
A0A5P8D6K8 509 5,27758
A0A7T1KSJ7 318 5,45247
G8IAV5 493 6,52139
A0A0K2FN79 491 5,26792
F1BCI8 513 5,53131
A0A2H4PEK0 500 6,14358
A0A076YK02 498 5,58616
A0A1L5C0I6 491 6,65632
A0A1D8EUB7 503 6,49200
A0A649VT43 499 5,45480
A0A2D1G875 489 6,21986
A0A1C9LYG9 491 6,17478
A0A6B9LD66 509 5,31367
G1BKY1 498 6,54139
K0G7U1 501 5,88991
A0A6B9JAY9 504 5,94675
B3VGG0 501 5,74230
A0A127KPE5 502 5,86814
A0A023W6P1 500 6,14364
A0A076YJF9 499 5,54347
A0A0A1EL78 500 6,14358
A0A0A7S1Y8 500 6,14364
A0A0K1LRP3 499 5,54347
A0A0M4RCN8 500 6,14364
A0A0N9SHB4 500 6,14364
A0A0S2MUX2 493 6,52144
A0A142K5K1 500 6,14358
A0A143FQE0 500 6,14358
A0A143FQU6 500 6,14358
A0A1B1SDW3 500 6,14358
A0A1B2IHS6 499 5,45480
A0A1C9LXF2 500 6,14358
A0A1D8EWP9 500 6,14364
A0A1D8EZW7 500 6,14358
A0A1J0GNX2 504 5,94675
A0A1J0GPQ4 500 6,14364
A0A1J0GQZ9 500 6,14358
A0A1J0GS71 500 6,14358
A0A1J0MAC4 500 6,14358
A0A1J0MAV5 500 6,14364
A0A1J0MAV6 500 6,14364
A0A1J0MB42 500 6,14358
A0A1J0MBC9 500 6,14358
A0A1J0MIX0 500 6,14358
A0A1L5C081 500 6,14364
A0A1L5C0Q7 500 6,14358
A0A1L5C120 500 6,14358
A0A1L5C173 500 6,14364
A0A1L5C1J3 500 6,14358
A0A1L5C1S9 500 6,00699
A0A1L5C1Z2 500 6,14358
A0A1S5VYI9 467 6,25675
A0A1U9WRF0 500 6,14364
A0A249XPJ1 498 6,54145
A0A2D1GC52 500 6,14358
A0A2L0HKB5 499 5,54347
A0A2L0HKM7 499 5,45480
A0A2L1IYS4 503 5,45480
A0A2P1CIP5 500 6,14364
A0A2P1CKH8 500 6,14364
A0A2P1JRY3 499 5,45139
A0A2P1JTE2 498 5,51011
A0A2P1JZD7 500 6,14358
A0A2P1N4T8 500 6,14358
A0A2R4AMN5 500 6,14364
A0A2S1PC60 500 6,14364
A0A2U8UGX7 500 6,14358
A0A2U8UQ28 500 6,14358
A0A2U8UR00 500 6,14358
A0A345BMQ5 500 6,14364
A0A345BMZ2 500 6,14364
A0A345KQU9 500 6,14358
A0A345KRD0 500 6,14358
A0A345KV98 500 6,14364
A0A345L2R1 500 6,14364
A0A345MES3 499 5,45480
A0A385D3B0 500 6,14358
A0A385UGL0 500 6,00341
A0A386KP38 500 6,14358
A0A3S9UNH1 500 6,14358
A0A411BPM3 500 6,14358
A0A411BQR2 500 6,14358
A0A411BZI1 500 6,14358
A0A411C0F2 500 6,14358
A0A411C9P6 495 6,19860
A0A411CIK9 500 6,14358
A0A482J538 493 6,38316
A0A482J5C8 500 6,14540
A0A482JAT5 500 5,88144
A0A482JB82 500 6,14364
A0A482JBQ4 498 6,77807
A0A482JCV7 500 6,14364
A0A482JDQ4 499 6,14358
A0A482JIN0 500 6,14358
A0A4D6T551 503 5,45480
A0A4Y6EE87 500 6,14358
A0A516KSD2 492 5,78322
A0A5J6TTB8 499 5,45139
A0A5P8D906 490 6,10243
A0A5P8D9J7 498 6,54139
A0A6B9J0V2 500 6,14364
A0A6B9LGE2 499 5,54347
A0A6G9LCY6 500 6,14358
A0A6N0A5N3 500 6,14358
A0A6N0A7B5 500 6,14364
A0A7D5BVT9 500 6,20087
A0A7G3WHY6 500 6,14364
A0A7G8LGT1 499 5,54347
A0A7G8LLL9 500 6,14364
A0A7L7SY99 500 6,14364
A0A7M1CNZ3 500 6,14358
A0A7M1CQ50 491 5,26792
A0A7M1CQ62 500 6,30102
A0A7M1CRP7 500 6,14358
C9DBZ2 500 6,14358
E0YQ83 500 6,14358
F6MDN6 500 6,14364
G1FN47 500 6,00483
G1JZU3 500 6,14364
G8I7H5 499 5,54347
I3WUE4 500 6,14358
I3WWF2 500 6,14358
K0G888 500 6,14358
R4JFB3 500 6,14364
R4JML6 498 5,58974
S5VLT4 503 5,54347
S5YC11 500 6,14358
W0LIP7 500 6,14364
W0LJS5 467 6,25675
W0LMC4 500 6,14358
A0A0M4RS64 499 5,45480
A0A0Y0C4K2 499 5,45480
A0A2R4ANA2 499 5,45480
A0A385D3E5 499 5,45480
A0A385UDM1 499 5,45480
A0A3G8FFV5 499 5,45480
A0A4D6E1N0 499 5,45480
A0A5P8DBX3 499 5,45480
A0A649VTM6 499 5,45480
A0A8A1V8Z5 318 5,45247
A0A8A1VHG3 318 5,45247
A0A8F2IGK8 500 6,14358
A0A8F3ECF9 512 5,97619
A0A977PSR0 495 4,99788
A0A9E7QDC3 499 5,45480
A0A9E7QJP5 498 6,35525
A0A9E7TZZ2 503 5,45139
A0A9E8M6S9 496 6,49541
A0AAE7SJ07 493 6,65712
A0AAE7XAN5 498 5,58974
A0AAU8GR33 501 5,88684
A0AAX4M1E7 499 5,45480
G8I3I5 499 5,45480
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_7770
7cDMo
 152 46,7% 325 1.561E-135
2 phalp2_15548
8sEzo
 71 46,1% 334 7.754E-127
3 phalp2_11453
8MIMB
 173 21,3% 352 7.105E-21

Domains

Domains [InterPro]
Unannotated
Unannotated
Unannotated
Representative sequence (used for alignment): 8Jrom (504 AA)
Member sequence: W0LN01 (494 AA)
1 504 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Mycobacterium phage Nyxis
[NCBI] 		1445714 Backyardiganvirus > Backyardiganvirus peaches
Host Mycobacterium smegmatis str. MC2 155
[NCBI] 		246196 Actinobacteria > Actinobacteria > Corynebacteriales > Mycobacteriaceae > Mycobacterium >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
KF954506 [NCBI]
CDS location
range 3921 -> 5405
strand +
CDS
ATGGCACGCCGACTCTTCAGGGGTCGGGCTTTCTCCGAGAACGGTTGGCCTTACGTCGACCAGGGTTCGTGTACGTGGGTGGAGGTTGTTCCCGGAGTCTGGCTCCAGTTCCAGAACGGCCCCTGCCTCACGGTCATGGTCGCGTTCGCTCGGGACTTCCACGCCCACGTCGAACCCCTCCGGGACTACGACTCCGCGTGCTGGACCCAGGACAACACCGTCGATACCAGCAACCACCCCGGTGGCACCGGGATGGACCTGAACTGGAACGGCGCTGACCAGAAGACCTTCCGCTACGGCATCACGAAGGAACGCGCCTACCCCGGCGACAAAGCCCGCAAGCTCGATGAGCTGCTGGCCTTCTACGAGGACGTGATCTACTGCGGCGGCTACTGGAGCATCCGCGACTGGATGCACTTCCAGATGGGCTACGGCACTTACGACTCGAAGGCCGACCGGCCCACTGAGAAGACGCTCGACTTTATCCGGCGCAAGATCAGGCCAGACGGCTTCTCGACGTTCAATCGCGGTGGCAGCGCAGCTCCTGACGCGGCGTCGATCCTCGCTCGGGCTACCGGCATCCCGCTGGACAGGGCAAGGACGGTTCTGCCCACCCTGCGTGACGGGCTGATCCAGGCCGAGTGCAACACGTTCCCCCGGATCGCGATGTTCCTCGCACAGACGTGCTGGGAGTCCGATCAGTACCGGGCGACCGAGGAGTACGCCAACGGCCCGATGAACGAGGAACGCTGGATTTACAAGGGGCGCACCTGGATTCAGCTTACCTGGCGTTCGGCCTACGAGGGCTTCGGCCGCTGGTGCCACGCTCGAGGGCTGGTGGACGACCCGATGGTGTTCGTCAACAACCCCCGGTCGCTGGCCGACCTGCGGTGGGCCGGCCTTGGCGCTGCCTACTACTGGACGACGACCGTCCGGAACACGCGGAAGTACCCGACGCTCAACCAGGCATCGGACGCCCGCGACGTGCTGGTCGCCACGCAGATCGTCAACGGCGGCACCACGCATCTGGCAGAACGCACGGCCATCTACAACCGCGCCATCGCCCTCGGCGATGAGTTGCTTCACATCCTCGGAGAGGAGGAGGACTTCTTGTCCGCACTCAATCCCCAAGAGCAGCGACTGCTGTTCGACAAGACGCTCCAGGTCTGGGGCGCACTGTTCAACAAGGTCGAGTCCAAGTCGGGCTACCGCAACCCCGGTGGTACGAGCGATCCCGCCAACATGTGGGCCGTCAAGGACTACGTCAGCAACATGGACGGGTTCATCCACGAGGACTTCGTGGAGTCACAAGCCAAGCGCGGCAACATGACTGAGCTCGCTCGCGTCGTCCAGGCCGCTCGCGGCCGGGGCGCTGACACGAGCCCTGGGTTCGTCGCCCGCGCACAGCGCGTGCTCGCGGAGATCGAGCGAGACGACCCCGAGATTCTCCAGAGATTCCTCGCAGCAGAAAGGGGGGCTGCATGA

Gene Ontology

No Gene Ontology terms available.

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (8Jrom) rather than this protein.
PDB ID
8Jrom
Method AlphaFoldv2
Resolution 90.00
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50