Protein

Protein accession
I6PD81 [UniProt]
Representative
6SdLA
Source
UniProt (cluster: phalp2_320)
Protein name
NlpC/P60 family protein
Lysin probability
100%
PhaLP type
VAL
Probability: 99% (predicted by ML model)
Protein sequence
MDETLIQEIKRHAAQTYPQECCGLVILQDGQPRYLPCRNTADNPAAHFRIAPEDYARAEDQGDVVGIVHSHPDATSQPSELDKAQCDVTELPWHILSWPEGDLRTIYPRGELPLIGRSFVLGVYDCWGLIMSYFRQEHGIELRDYRVDYHWWEAGHTENFYQDCWYECGFREFDGPPQPGDMVIMQVSAPRWNHAGILLEGNMLLHHLYGHQSGRTPYGGYWRERTMKIVRHKDLMGEV
Physico‐chemical
properties
protein length:239 AA
molecular weight:27712,9 Da
isoelectric point:5,29
hydropathy:-0,58
Representative Protein Details
Accession
6SdLA
Protein name
6SdLA
Sequence length
72 AA
Molecular weight
8081,22820 Da
Isoelectric point
5,32265
Sequence
MIALVHSHPDATTQPSELDKAQCDATLLPWHIVSCPEGDLRTIQPRGELPLLERPFVLGHFDCWGLVMSSFR
Other Proteins in cluster: phalp2_320
Total (incl. this protein): 34 Avg length: 232,7 Avg pI: 5,33
Protein ID Length (AA) pI
6SdLA 72 5,32265
K7PM21 243 5,30680
A0A482IM20 236 5,61492
G8C7J8 236 5,25712
K7P7C3 236 5,18010
K7P6J4 236 5,26400
K7PJV6 236 5,34977
K7PLS6 236 5,48379
K7PGV2 236 5,38222
Q9MCU3 236 5,34977
Q9MCS0 236 5,02692
K7PJX1 236 5,19886
A0A220NRQ4 236 5,10303
K7P6F5 236 5,27894
K7P854 236 5,58951
A0A2Z2EK93 236 5,47174
K7P7M8 243 5,30685
K7PGR2 236 5,47299
A0A1P8DTI6 236 5,69495
O64333 243 5,48499
F1C573 234 5,01538
Q6UAW4 236 5,53802
A0A1W6JP31 232 5,40712
A0A2Z5H0A9 236 4,84651
A0A481W2K5 237 5,56104
A0A5Q2F975 251 5,31151
A0A653FU65 236 5,38222
A0A6B9WIS1 236 4,83605
A0A7T6ZMB5 233 5,41411
A0A6G5YEG5 239 5,67409
A0A8S5N0C5 236 4,96076
A0A9Y0T803 253 5,46242
A0AAT9V517 236 5,47174
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_21954
7CibD
 5 36,1% 72 2.299E-14
2 phalp2_22357
8J1ik
 4 34,7% 69 3.844E-08

Domains

Domains [InterPro]

No domain annotations available.

Taxonomy

  Name Taxonomy ID Lineage
Phage Cronobacter phage phiES15
[NCBI] 		1168280 No lineage information
Host Cronobacter sakazakii ES15
[NCBI] 		1138308 Proteobacteria > Gammaproteobacteria > Enterobacteriales > Enterobacteriaceae > Cronobacter >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
JQ780327 [NCBI]
CDS location
range 31439 -> 32158
strand +
CDS
ATGGACGAAACACTGATTCAGGAGATTAAGCGGCACGCGGCGCAAACCTACCCGCAGGAGTGCTGCGGGCTTGTCATTCTGCAGGACGGCCAGCCGCGTTATCTCCCCTGCAGAAACACCGCAGACAACCCGGCGGCGCATTTTCGCATCGCGCCGGAGGATTACGCCCGCGCCGAAGATCAGGGCGACGTGGTAGGCATCGTTCACAGCCACCCTGACGCCACCAGCCAGCCGAGCGAGCTGGATAAGGCGCAGTGCGACGTTACAGAGCTGCCCTGGCATATCCTGAGCTGGCCCGAGGGCGATTTACGCACCATCTACCCGCGGGGTGAGCTGCCGCTGATTGGCCGCTCGTTTGTGCTGGGCGTCTATGACTGCTGGGGGCTGATTATGAGCTATTTCCGGCAGGAACACGGGATCGAGCTGCGCGACTACCGCGTTGATTATCACTGGTGGGAAGCCGGGCACACGGAAAATTTTTATCAGGATTGCTGGTATGAATGCGGTTTCCGGGAGTTCGACGGGCCGCCGCAGCCGGGCGACATGGTGATCATGCAGGTAAGCGCGCCGCGCTGGAACCACGCCGGGATTTTGCTGGAGGGCAACATGCTGTTGCATCACCTGTACGGGCACCAGTCGGGGCGCACGCCTTACGGGGGCTACTGGCGTGAACGAACCATGAAGATTGTGCGCCACAAGGATCTGATGGGGGAGGTATGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0006508 proteolysis biological process None (UniProt)
GO:0008234 cysteine-type peptidase activity molecular function None (UniProt)
GO:0008235 metalloexopeptidase activity molecular function None (UniProt)
GO:0008270 zinc ion binding molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi00025f6875_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (6SdLA) rather than this protein.
PDB ID
6SdLA
Method AlphaFoldv2
Resolution 95.21
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50