Protein

Protein accession
A0A4Y5FGK4 [UniProt]
Representative
5tXTi
Source
UniProt (cluster: phalp2_28907)
Protein name
Tail lysin protein
Lysin probability
100%
PhaLP type
VAL
Probability: 99% (predicted by ML model)
Protein sequence
MASSTSSNQVADTSQLEVPRTNVEFTVNFYTISGVYPVIARTTYNFSTQEQNSFNNGLINFQTQNDAGNGDAPSFTVELNDTYEWDSVLSPNDYIRIDAKVWSELNASGYQSSSDVQTSTLMTGLISSITKTTTAGSNERVYTIAGQGMAKVPLNLNLDTFSELTSSLSGYQMIPDEEKKGIRFSQRTSANIIQQVWNRFVLNQDGDFVNYSYYDGQLMNKLTDLIKLNLQENRDESMMTGSYNQYQNPNMSVYKMIDGLSAKPFNEYFWTHEDGVATFNYRPTPYDPEAWNALDVVSLSPDAIINDQTNVTDENQASIFKLLAYSGYGSETYSGGWSGHLAPLTNLDLVQKYLYKLMEVPCDYFNGNKGESGKDSEEINNTNVNLSSKVKSYYSLAKKVCEDKKVSDWLPYVMAILQQESKQAGRNDIANTKGNLGKESKTKKTSIENLVDYLKAGEKKGKSLSPKVDDKLSVVHSYQYGGYGFLDKESSSNDSSFSLNDAEEYSKSYAKTHGNPNAVTSKYITTLSRKYGKEYLYKHGGNFYYALEVKGYLGSTNDDASQSSSNSTVPSSEGTTEHQASLHYPPYESLENAFNTAKEGKKKRTESEKKSDASLTIPSDYGGHGEYDVVIGILKGPGSKEDKLKDIQESSSGYEHKISKGMADLLYSKYKVANTKDKLPISGYLSIIAPNYNPTNGNLARSTKYLKSNASIKAHPKKAALELMSLFNYTLGSKQAYEIIKAYIKNGYKLSPDEYAAILKKYGYNETEAGVNPETSNGSSNGVPYLFRKYTEKLFNWFADESKYHSGDIIVSGILGVEIGKRLRFYDKKLGVYWEYYIEGVSHSFDYSTGQWTTDIGVTRGIALDSLDDNRRFTNPWSYWGLYTEFKGGYFGEPTMAQDEATYASSDNSSDDSDDGDTGGVVLKGKKGKKAAADAAAFGYSKRKSVYKNEHYSQPRRMYPRSSNPLDKKSGEIILDCSSFVYWCFKKQGVTIGANTGEDMSDSHFKHMGNIPTSKMLIGDCLELGHNRSYPEHIVMYIGGGKTIGWNGNDVNWDASGGAKVNTVSFWRKNMGIVTVLRLK
Physico‐chemical
properties
protein length:1080 AA
molecular weight:120287,0 Da
isoelectric point:6,04
hydropathy:-0,66
Representative Protein Details
Accession
5tXTi
Protein name
5tXTi
Sequence length
860 AA
Molecular weight
94344,93180 Da
Isoelectric point
5,13781
Sequence
MRNLYTLKANMTITFYTVDGSYPVVSRAVDNQVSPGSHQAFYNGLISFQTKNDTSEDIPTATIVLTDDYDWSSILVPNDYVVITAGYRGDMPYSDKNTTVNSTLYCGLVTDIMKTGSYGDNNANRTFTITVQGMAKVLQSMNLSTFSEITSTLNGYQMLPDDEKTGIAFSGKSSAVLIDEVLKKFILNNNEYTKYLFQDENGQQFSLESLLQTQLQPNTDEAFASNSNNQFMNYNGTILQMVKDMAVRPFNELYWTHEQGVATLHYRPTPFEQSEWTALEEIDLSSDNIISEEVRANDAEQSSIFKLLATDDAGSQLTTTGFSGSIYPLTNRALIQRYGYKTMEVQTPYFSGESNSDDSSYGGTSEAGKGKTESEAQLHYPSYGNIQDYFALARGVNGTDDYDVPPEHGGNHTYDSLLSSLKGGASQSAFVSQATDTGFISETQANNLYAKYKSSGNGTLNKQAYLSIVAPNYNPTSTNVSYSSTYLKSVSKMKDDPEKAAMELMQESKYTLGSKQAYDLVQAAIASKGNVSKATYQKILGEGYNAKQDGVDILSADGSGNQDAVSLLFQMYTQKLFNWYADNSKFHSGTITVQGTLGIENGKRLVVYDNKEKVYWEYYIESVGHNFSYTQGWTTQIGVTRGLALPNQGDTTRRYGFPYSFWGTYEQFVGGYFGEQSMADAVAAADSASGGSDDTSGGSVSGGGDDKFSSGGKTATKAVELASGLSKKAGAGSYNQSYHTQDPFNMSSPKGDCSSLVYFAYKHAGVNLSNGGWTTWKLAKSDKLKTIGSSGSNKDDVYKKMHVGDLIFFKTTAKDDSHVGLVMSDGIIAWNTKKGVSTFSLKSSNYWWNAWRGHCMRLKE
Other Proteins in cluster: phalp2_28907
Total (incl. this protein): 21 Avg length: 982,1 Avg pI: 7,13
Protein ID Length (AA) pI
5tXTi 860 5,13781
28x8d 1062 8,72046
3xPYl 1081 7,49191
5N1CD 1035 4,90699
5oeuJ 880 4,97679
5osb7 1026 4,94882
5osdM 1021 4,92126
7AoOz 1027 8,48367
7zOqP 1028 8,69061
7zOwx 1030 8,85636
81LrB 1056 4,64581
8LlRD 1038 8,38058
8LmMN 1035 8,87970
8LseK 1080 6,04013
A0A3S7UP23 1030 8,85636
A0A3S6QAA7 1035 8,87970
Q5ULI0 1062 8,76939
A0A3Q8HYG9 1027 8,81349
A0A6G5XWY1 404 7,76412
A0A6G5YFL1 728 5,54160
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_11331
7jPy7
 2 36,9% 603 6.051E-169
2 phalp2_37189
1QZtJ
 98 28,0% 884 6.530E-111
3 phalp2_11026
4Sv8d
 15 26,4% 717 1.444E-65
4 phalp2_33582
8LHfr
 135 25,4% 550 3.944E-46
5 phalp2_1764
2LOtm
 25 19,8% 848 6.720E-36
6 phalp2_5245
7YnjZ
 6 21,2% 904 1.641E-32

Domains

Domains [InterPro]

No domain annotations available.

Taxonomy

  Name Taxonomy ID Lineage
Phage Lactobacillus phage 3-521
[NCBI] 		2510943 Herelleviridae > Watanabevirus > Watanabevirus wv3521
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MK504444 [NCBI]
CDS location
range 57260 -> 60502
strand +
CDS
ATGGCAAGTAGTACATCATCAAACCAGGTAGCAGATACTAGTCAATTAGAGGTACCAAGAACTAATGTTGAATTTACTGTTAATTTCTATACAATTAGCGGCGTGTACCCTGTAATTGCTAGAACAACATACAACTTTAGTACCCAAGAGCAAAACTCTTTTAATAATGGCCTAATAAACTTTCAGACACAGAATGACGCTGGAAATGGGGATGCCCCCTCTTTCACTGTTGAGCTAAATGATACGTACGAGTGGGACAGTGTACTATCTCCTAATGATTACATTAGAATTGACGCTAAGGTATGGTCCGAATTGAATGCAAGTGGTTATCAGAGTTCTTCTGATGTACAAACTTCTACTTTAATGACAGGGTTAATAAGTAGTATTACTAAGACAACTACTGCGGGTAGTAACGAGCGAGTATATACCATTGCTGGTCAAGGTATGGCTAAGGTACCTCTTAATCTTAATCTGGATACTTTTTCTGAGCTAACTTCTTCCTTAAGTGGTTATCAAATGATACCTGATGAAGAAAAGAAAGGTATTAGATTCTCTCAAAGAACCTCTGCCAATATTATTCAGCAGGTGTGGAATAGGTTTGTACTTAATCAAGATGGAGACTTTGTAAATTACAGCTATTATGATGGTCAGTTAATGAACAAGCTTACTGATTTAATAAAGTTAAATTTACAGGAAAACAGAGATGAGTCCATGATGACGGGTTCTTATAATCAGTATCAGAACCCTAACATGAGTGTGTATAAGATGATTGATGGATTGTCCGCTAAGCCTTTTAACGAGTATTTTTGGACTCATGAGGATGGGGTTGCAACCTTTAATTATCGTCCAACACCTTATGACCCAGAGGCTTGGAATGCTTTAGATGTTGTAAGTTTGTCACCAGATGCTATTATTAATGACCAAACTAATGTAACAGATGAAAATCAAGCATCTATTTTTAAGTTACTTGCCTATAGTGGGTATGGGTCAGAAACTTACTCTGGTGGTTGGTCAGGACATCTGGCACCCTTAACTAACTTAGATTTAGTACAAAAATACTTATATAAGCTCATGGAAGTACCCTGTGATTACTTCAATGGTAACAAGGGGGAGTCTGGTAAAGATTCAGAGGAGATAAATAATACTAATGTTAATTTATCTTCAAAGGTTAAGTCTTATTATTCTCTAGCTAAGAAAGTATGTGAGGACAAGAAGGTTTCTGACTGGTTACCTTATGTAATGGCTATTCTACAGCAAGAAAGTAAACAAGCAGGTAGGAATGATATTGCAAATACTAAGGGTAATCTTGGTAAGGAATCTAAAACTAAGAAAACATCTATTGAAAACTTAGTAGATTACTTAAAAGCAGGTGAAAAGAAAGGCAAAAGTTTGTCACCAAAAGTTGATGATAAACTATCAGTAGTGCATTCTTATCAATACGGCGGATATGGGTTTCTTGATAAGGAAAGTAGCAGCAATGATTCATCCTTTTCCTTAAATGATGCTGAAGAGTATTCAAAGTCATACGCCAAGACGCATGGTAATCCTAATGCTGTTACTAGTAAGTACATCACAACATTATCCAGAAAATATGGTAAGGAATACCTGTACAAACATGGTGGTAACTTTTACTACGCTTTAGAGGTTAAGGGTTACTTAGGGTCTACTAATGATGACGCTTCACAAAGTTCCAGTAATAGTACTGTTCCATCTAGTGAGGGGACTACTGAACATCAAGCTTCTTTACACTATCCCCCGTATGAAAGCCTAGAAAATGCTTTTAATACTGCTAAAGAGGGTAAGAAAAAGCGTACAGAGTCAGAAAAGAAGTCAGATGCCAGCTTAACTATTCCTAGTGACTATGGAGGCCATGGTGAGTACGATGTTGTTATTGGAATATTAAAAGGTCCTGGAAGCAAAGAAGATAAGCTAAAGGATATTCAGGAATCTAGCTCTGGTTATGAGCATAAAATCAGTAAGGGTATGGCAGACTTATTATACTCTAAGTACAAAGTAGCAAATACTAAGGATAAACTACCTATTAGTGGGTACTTAAGTATTATTGCTCCTAATTACAATCCAACTAATGGTAACTTAGCTAGAAGTACTAAGTACCTAAAGAGTAATGCCTCTATTAAAGCACACCCTAAAAAGGCTGCTTTAGAGCTAATGTCTCTGTTTAACTATACTTTAGGGTCTAAACAGGCTTATGAGATAATCAAGGCATATATCAAGAATGGGTATAAGCTTTCTCCAGATGAGTATGCTGCTATACTTAAAAAGTACGGGTATAATGAAACAGAAGCTGGTGTTAATCCTGAAACTTCTAATGGTTCTTCTAACGGGGTACCTTATTTATTCAGGAAGTACACAGAAAAGCTATTTAACTGGTTTGCAGATGAATCTAAGTATCATTCTGGTGATATCATAGTTAGTGGTATACTAGGAGTAGAGATTGGTAAGAGACTGAGATTTTATGATAAAAAGTTAGGAGTATACTGGGAATACTACATTGAGGGTGTTAGTCATAGCTTTGATTATAGTACTGGACAGTGGACTACTGACATCGGTGTAACTCGGGGAATTGCTCTTGATTCCTTAGATGATAACCGTCGTTTTACTAATCCTTGGAGTTACTGGGGTCTGTACACTGAGTTTAAGGGTGGGTACTTTGGTGAACCTACTATGGCTCAAGATGAAGCAACCTATGCTAGTTCAGATAACTCATCAGATGATTCAGATGATGGTGATACCGGGGGAGTAGTCCTTAAGGGTAAAAAAGGTAAAAAAGCGGCGGCTGATGCAGCAGCTTTTGGATACAGTAAGCGAAAAAGTGTATATAAAAACGAACATTATTCCCAACCAAGACGAATGTATCCTAGGAGTAGTAATCCCCTGGATAAAAAGTCAGGAGAAATTATACTAGATTGCTCTAGCTTTGTTTATTGGTGCTTCAAAAAGCAAGGAGTTACCATTGGAGCAAATACTGGGGAAGACATGAGCGATAGTCATTTTAAGCATATGGGTAATATACCAACCAGTAAAATGTTAATTGGTGATTGTTTGGAACTTGGACATAACCGTTCTTATCCTGAACATATCGTTATGTACATTGGTGGTGGAAAAACTATCGGTTGGAATGGTAATGATGTTAATTGGGATGCTAGTGGTGGTGCCAAAGTTAATACTGTTTCTTTTTGGAGAAAAAATATGGGGATTGTAACAGTTCTTAGGTTAAAATAG

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008234 cysteine-type peptidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (5tXTi) rather than this protein.
PDB ID
5tXTi
Method AlphaFoldv2
Resolution 83.11
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50