Protein

Protein accession
A0A5H2QW34 [UniProt]
Representative
6wdij
Source
UniProt (cluster: phalp2_19930)
Protein name
N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MKIGIRDGHSPNCKGAIGLRDEQSCMRVLCKEVIEILEKHGHEVVYCGSDASTQNGELSEGVRKANNSNVDIFISLHMNSFNGQAQGTEALVTVGARNSIKEIASRLCKNFASLGLVNRGVKEVNLYEMKNVKAPNIIFETMFCDNPHDINEVWSPTPYEKMALLIANAIDPTIKENELYRVVVQYFNNKKDAENCQQEIAKRWYCFVEECN
Physico‐chemical
properties
protein length:212 AA
molecular weight:23862,9 Da
isoelectric point:5,79
hydropathy:-0,37
Representative Protein Details
Accession
6wdij
Protein name
6wdij
Sequence length
244 AA
Molecular weight
26476,17440 Da
Isoelectric point
4,57084
Sequence
MHIAIAGGHSAIARGASGYLDEYECDRAFVAQLIEAFDAQGWYVTDCSNEESDVSAELREECRIANASGADLFIAVHFNAGGGTGTEVWYYPYSLAETCAREVSRELASALGLPNRGAKSTAGLYVLNHTEMPAILIEVCFVDTEQDADAWHATSWNALCGAVVRGLGGDYVNKEEDMLTEHQDKLLATIYEQVTGTYDPTGRGVEMNDHDHIKWIGKKVADNAAAIQAVDAKLDKLIEKLGQL
Other Proteins in cluster: phalp2_19930
Total (incl. this protein): 24 Avg length: 232,3 Avg pI: 5,36
Protein ID Length (AA) pI
6wdij 244 4,57084
414GS 242 5,03056
5VUZp 242 4,70578
5X3MR 242 4,63729
5Zh2A 242 4,52174
62YEE 242 4,67071
65fsS 242 4,45251
66U18 242 4,53379
6dJTl 241 4,39777
6gCrI 242 4,48513
6mNVq 244 4,58949
6nmL9 242 4,61938
6qky9 242 4,50269
6qsLn 242 4,56101
6vq1j 242 4,70578
80hBI 244 4,51014
82ryt 213 9,11398
82u1t 214 9,45688
F8UBD2 212 6,44556
G9J3I1 212 5,61731
F8UBN3 212 6,89300
A0A5H2QVV1 212 6,12658
A0A976XLE2 212 5,79766
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_36719
6eCmw
 993 40,0% 175 1.356E-52
2 phalp2_35186
67E6C
 93 38,8% 175 3.069E-48
3 phalp2_27800
7z5TK
 19 35,1% 182 7.853E-48
4 phalp2_8961
3yVzG
 53 40,1% 167 5.139E-47
5 phalp2_19905
69yEp
 107 30,6% 183 5.916E-40
6 phalp2_6374
7yZe6
 41 39,0% 169 9.819E-39
7 phalp2_23331
5tGuH
 43 35,8% 198 9.981E-34
8 phalp2_15683
35AAr
 164 38,5% 179 6.818E-31
9 phalp2_22023
5iret
 1 30,6% 183 4.585E-28
10 phalp2_19262
8ev89
 7 32,9% 167 1.039E-24

Domains

Domains [InterPro]
Ami3
Unannotated
Disordered region
Representative sequence (used for alignment): 6wdij (244 AA)
Member sequence: A0A5H2QW34 (212 AA)
1 244 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01520

Taxonomy

  Name Taxonomy ID Lineage
Phage Clostridium phage CPD2
[NCBI] 		2420237 Guelinviridae > Gregsiragusavirus > Gregsiragusavirus CPD2
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MH999279 [NCBI]
CDS location
range 10909 -> 11547
strand +
CDS
ATGAAAATAGGTATTAGAGACGGACATAGTCCAAATTGTAAGGGTGCTATTGGTTTACGTGATGAACAATCATGTATGAGAGTTTTATGTAAAGAGGTTATAGAAATATTAGAAAAACATGGGCATGAGGTAGTTTATTGTGGTAGTGATGCAAGTACACAAAATGGTGAACTTTCAGAAGGTGTAAGAAAAGCTAATAATTCAAATGTTGATATATTTATTTCATTGCACATGAATAGCTTTAATGGGCAAGCCCAAGGAACAGAGGCACTTGTTACAGTTGGAGCAAGAAATTCTATAAAAGAAATTGCCTCAAGGTTATGCAAAAACTTTGCTAGTTTAGGTTTAGTAAATAGGGGTGTAAAAGAAGTTAATTTATATGAAATGAAGAACGTAAAAGCACCCAACATAATATTTGAAACTATGTTTTGCGATAACCCCCATGACATTAACGAAGTTTGGTCGCCTACACCATACGAAAAAATGGCTTTACTAATTGCAAATGCTATTGACCCAACTATTAAAGAAAATGAACTTTATAGAGTTGTTGTTCAATATTTTAACAACAAAAAAGATGCTGAAAACTGTCAACAAGAAATTGCTAAAAGATGGTATTGTTTTGTGGAGGAATGTAATTAA

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (6wdij) rather than this protein.
PDB ID
6wdij
Method AlphaFoldv2
Resolution 87.39
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50