Protein

Protein accession
A0A345MEC8 [UniProt]
Representative
1Nc5e
Source
UniProt (cluster: phalp2_39986)
Protein name
Hydrolase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MYSKKTAVIGTLLSAMGLVVSIPVSAEAATIQEKANSVAKAQIGDPYVWGGKGPNKFDCSGLVWYSFKQAGKNWSYQPTNGMRKNQTKDITVSQRKVGDLIFFRRKGSSDWSHVGIYAGSGYMVNAVNGNTYKGVRKGKVVDGYWNKYYNADYRRVK
Physico‐chemical
properties
protein length:157 AA
molecular weight:17395,6 Da
isoelectric point:9,94
hydropathy:-0,48
Representative Protein Details
Accession
1Nc5e
Protein name
1Nc5e
Sequence length
275 AA
Molecular weight
28340,26010 Da
Isoelectric point
9,60078
Sequence
MLSRRISIVAVLVIALMLTVAPIVEATHSVSAGPETADEPRHNQTVPVPFGLYRQPKPIKPVAPVQTFTAVPPPPIGPVWTVNKYVIKSGDTLSAIAPALKSNFSELARCSGISNPNRISIGQIIHKPGTGTCIAPPLTQPAITANAAPINSVSSAAGIVISFAKAQLGDPYVWAGNGPNSWDCSGLMVAAFRQAGVTLPRTSRAQYTVGSSVAYGQWAPGDLLFYGSSASSIHHVALYIGGGQLIHAPQAGDVVRAAAAPAGGGGDYLGAKRVL
Other Proteins in cluster: phalp2_39986
Total (incl. this protein): 7 Avg length: 189,6 Avg pI: 9,35
Protein ID Length (AA) pI
1Nc5e 275 9,60078
dDV6 275 5,50937
A0A345M702 155 10,03194
A0A386KAJ2 155 10,31631
A0A4D6E069 155 10,03194
A0A7T0M1N8 155 10,03194
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_39637
6Kn72
 20 37,7% 172 8.158E-30
2 phalp2_32044
5EFHm
 2 35,7% 221 5.209E-27
3 phalp2_13707
6wZHy
 3 35,8% 198 7.021E-25
4 phalp2_17414
4QxTJ
 15 36,5% 194 2.746E-23

Domains

Domains [InterPro]
Disordered region
Unannotated
Unannotated
Representative sequence (used for alignment): 1Nc5e (275 AA)
Member sequence: A0A345MEC8 (157 AA)
1 275 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Streptomyces phage SparkleGoddess
[NCBI] 		2283305 Stanwilliamsviridae > Gilsonvirus > Gilsonvirus comrade
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MH590589 [NCBI]
CDS location
range 113046 -> 113519
strand +
CDS
ATGTATAGCAAGAAGACTGCGGTTATCGGAACGCTTCTTTCAGCAATGGGATTGGTGGTTTCGATTCCTGTAAGTGCTGAAGCTGCTACTATTCAGGAAAAGGCGAACAGTGTAGCTAAGGCTCAAATTGGTGACCCGTATGTTTGGGGAGGCAAGGGGCCGAATAAGTTCGACTGTTCCGGTCTTGTTTGGTACTCATTCAAGCAGGCGGGAAAGAACTGGAGCTATCAGCCAACCAACGGAATGCGGAAGAATCAGACAAAGGATATTACAGTCAGTCAGCGTAAGGTTGGTGACTTGATTTTCTTCCGTAGGAAGGGTTCTTCTGACTGGAGTCATGTTGGTATCTACGCTGGTAGTGGATACATGGTTAACGCTGTAAATGGAAACACATATAAGGGTGTTCGCAAGGGTAAGGTAGTTGATGGGTATTGGAATAAGTATTACAATGCCGACTACCGCCGCGTAAAGTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008234 cysteine-type peptidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (1Nc5e) rather than this protein.
PDB ID
1Nc5e
Method AlphaFoldv2
Resolution 69.04
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50