Protein

Protein accession
A0A385ISV1 [UniProt]
Representative
7lm13
Source
UniProt (cluster: phalp2_23542)
Protein name
MurNAc-LAA domain-containing protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MYIENILKTRKLRIGLRAGHSPNCLGAIGLRNEHTTMMVYYKYVKECFEKYGHTVIDCNSTANTEKAEVYEGINKANNAGVDIFISLHMNSYNGKAFGVECLVANGSRVWDVAERICEEYSKIGFFNRGVKIGNQWEMKDLNAPNIIFETCFCDSQKDIDIWSPCPYETLTRALCHAVDPSIPLTDEPDYYRVVVQRFKTKEDAEKAENKIKNDLGLYCFTEKI
Physico‐chemical
properties
protein length:224 AA
molecular weight:25626,0 Da
isoelectric point:6,00
hydropathy:-0,39
Representative Protein Details
Accession
7lm13
Protein name
7lm13
Sequence length
531 AA
Molecular weight
58837,41050 Da
Isoelectric point
8,98942
Sequence
MATPIMGTSKATIEQCELFLHNVNPKAPYLANIYKKYCDIYGIKLEIAWVQMCLETNFLRYSDTSITTLDMHNYAGLGALDGNGRKQALKFNTKNEGVECHIQHLFAYCSRNNLPQQQLIDPRFKYVDRGCAINVEDLGSGKWASDKQYANKLLDLLGRLTNTKIEKKGDNVMSKGMISYDFGHMEGGEDTSANGILYEYSIVRNYGSVVVRELQKAGYTLVNCTPPNGRMSLSQSLSYRVNKANSSGSMLHLCFHANCYNGNAYGCEMEVASDSSARIGQSIQNEVVSSLGFANRGVKRPSLYVTRNTNMPCVLTEPFFIDNRGDCNKYNVEKLGCAIATGVLKALGNNYRPSTGGNNSSSSSSPSKPTAIVTASALNVREQKSTSSKILGVLSNNKSVEVYKVEGDWVHIYYPPHGGFISKQYVKLYNIPDSIVQKPNKPVEKKEEKKMDIILYFGYVDEYGANLLRDKLKLPVLSLADFKANTNLKNNVGRIYMVGGSEKPVSDTVLISSGGRYDTAQAVIEYIKKLK
Other Proteins in cluster: phalp2_23542
Total (incl. this protein): 6 Avg length: 325,2 Avg pI: 6,77
Protein ID Length (AA) pI
7lm13 531 8,98942
1btHY 524 8,51764
A0A5H2TJX5 224 5,99915
A0A977WLB5 224 5,62418
A0AAF0AF14 224 5,47271
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_31329
2etws
 8 27,3% 431 9.891E-30
2 phalp2_17729
7ikmD
 1 28,6% 332 1.408E-19
3 phalp2_30857
omqp
 3 25,8% 368 1.408E-19
4 phalp2_11791
82p55
 1 26,6% 375 3.692E-16

Domains

Domains [InterPro]
GLUCO
Ami3
SH3_3
Unannotated
Representative sequence (used for alignment): 7lm13 (531 AA)
Member sequence: A0A385ISV1 (224 AA)
1 531 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01520, PF01832, PF08239

Taxonomy

  Name Taxonomy ID Lineage
Phage Clostridium phage susfortuna
[NCBI] 		2316154 Guelinviridae > Susfortunavirus > Susfortunavirus susfortuna
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MH393889 [NCBI]
CDS location
range 10073 -> 10747
strand -
CDS
ATGTATATAGAAAATATTTTAAAAACTAGAAAATTAAGAATAGGTTTAAGAGCGGGTCATTCTCCAAACTGTTTGGGAGCAATAGGTTTAAGAAATGAACATACTACCATGATGGTATATTATAAGTATGTTAAAGAATGCTTTGAGAAATATGGTCATACTGTAATAGATTGTAATTCAACCGCTAATACTGAAAAAGCAGAAGTTTATGAGGGTATAAATAAGGCTAATAATGCAGGTGTTGATATTTTTATTTCTCTTCATATGAACTCTTATAATGGTAAAGCCTTTGGGGTTGAGTGTTTAGTTGCCAATGGTTCAAGGGTTTGGGATGTTGCTGAAAGAATATGCGAGGAATATTCAAAAATTGGTTTCTTTAATAGAGGTGTAAAGATAGGTAATCAATGGGAAATGAAAGACTTAAATGCACCTAATATAATATTTGAAACTTGTTTTTGTGATAGTCAAAAAGACATTGATATATGGTCACCTTGTCCTTATGAAACTTTAACAAGGGCTTTATGTCATGCGGTCGACCCTTCAATACCTTTAACAGATGAACCGGACTATTACCGTGTTGTTGTTCAAAGATTTAAAACAAAGGAAGATGCTGAAAAAGCAGAAAATAAAATAAAGAATGACTTAGGATTATATTGTTTTACAGAAAAGATATAA

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7lm13) rather than this protein.
PDB ID
7lm13
Method AlphaFoldv2
Resolution 87.07
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50