Protein

Protein accession
A0A346FK38 [UniProt]
Representative
7yZe6
Source
UniProt (cluster: phalp2_6374)
Protein name
N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MAYNTVTYHAGHTQGGGARGSGYEESAVARQFAPVLAAAFAKVGQRTVDCTDNVSTTQNANINRLISLCNAVDSNGRLDISLHFNAADDASATGVEVLYYDQVGLARNVSAAIAKAAGYRDRGPKERKDLGVLRGTNAPAILIELAFITNADDMRKFFANMQAIANAIVQAVTGKTVSGGGSVPNSGGKWVLKTGGVGVPEAQECMNKLAEFGTKGSLVYEGNGIFYVITEPVTDRNALGAINWYFADYRKWFVELYQV
Physico‐chemical
properties
protein length:259 AA
molecular weight:27601,7 Da
isoelectric point:6,83
hydropathy:-0,09
Representative Protein Details
Accession
7yZe6
Protein name
7yZe6
Sequence length
230 AA
Molecular weight
24253,55890 Da
Isoelectric point
9,53528
Sequence
MTYSVVTVNAGHSAKAPGASGNGYREHEVARTLKDKLIKALNAVGQKTADTTSDAGDKNAVLAEQVRKCNAVIKNGRLDVAIHLNAGGGTGTEVLHFGASTKALAAKVSAAIAKAGGYRDRGAKQRQDLYFLRNTNAPSILIEVCFIDNADDMRKLMAQMDAIVNAIVKAITGKVAPAPAKPKSAYEIELEQAVDWAKAAGVSDGTRLNDACTRGQVIMMLYRLSKGAVK
Other Proteins in cluster: phalp2_6374
Total (incl. this protein): 41 Avg length: 255,5 Avg pI: 8,22
Protein ID Length (AA) pI
7yZe6 230 9,53528
11Bhu 249 8,68707
13rS3 229 7,58951
1rnSQ 228 9,20075
4jOyG 182 9,21706
4y7yU 231 7,58996
6pBHc 232 7,09489
74q2v 270 8,56387
74s5r 273 8,66721
74ssL 271 8,99374
74st9 271 8,57347
74zM3 274 8,76159
759La 271 8,87892
75UKl 271 8,69171
75Uga 290 8,82554
791ZI 229 7,59212
79zqE 290 8,59462
79zqW 290 8,77461
7BvcR 265 8,50443
7kNXl 229 6,90624
7nGnF 275 5,92020
7s6UG 263 9,60361
7t9sO 271 8,95835
7wN3a 247 8,53028
7x36Z 270 8,68610
7xQB3 290 8,57534
7xllJ 271 8,79621
7yzDW 271 9,06066
7zA6w 271 8,82161
7znZ4 231 9,45295
7znZ5 281 5,71297
82rHX 229 8,28530
82zV0 227 5,68540
88VQ8 238 5,19454
8IFbi 271 8,95841
8ono1 230 7,63253
fuS8 225 9,37249
oeGs 266 9,88328
A0A2I7QIN4 259 6,82991
A0AAE9LUP3 256 6,90346
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_36719
6eCmw
 993 43,0% 172 9.575E-61
2 phalp2_8961
3yVzG
 53 38,0% 168 7.737E-47
3 phalp2_33454
7e5ZG
 3 49,1% 177 6.942E-46
4 phalp2_29974
7ov8y
 34 41,2% 177 1.564E-41
5 phalp2_2704
7cWsF
 33 37,7% 175 1.210E-36
6 phalp2_15683
35AAr
 164 40,1% 182 1.654E-36
7 phalp2_12323
7wjSB
 3 41,3% 186 1.654E-36
8 phalp2_19930
6wdij
 24 37,6% 170 7.880E-36
9 phalp2_1315
Ystp
 399 36,9% 203 2.010E-35
10 phalp2_8747
8qMi4
 13 43,2% 192 7.005E-35

Domains

Domains [InterPro]
Ami3
Representative sequence (used for alignment): 7yZe6 (230 AA)
Member sequence: A0A346FK38 (259 AA)
1 230 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01520

Taxonomy

  Name Taxonomy ID Lineage
Phage Bacillus phage Wes44
[NCBI] 		2283012 Carmenvirus > Carmenvirus Wes44
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MH598512 [NCBI]
CDS location
range 23488 -> 24267
strand -
CDS
ATGGCTTATAATACTGTAACTTATCACGCAGGACATACACAGGGTGGAGGTGCACGAGGTAGCGGCTACGAGGAATCAGCCGTTGCCCGTCAATTTGCTCCAGTGTTAGCTGCGGCATTTGCTAAAGTTGGACAGCGTACCGTCGATTGTACTGATAATGTTTCTACTACTCAAAACGCTAATATTAACCGCTTGATTAGCTTGTGTAACGCAGTTGACTCAAACGGACGACTTGATATCTCATTACACTTCAATGCTGCTGATGATGCTTCAGCTACAGGCGTAGAGGTGCTGTATTACGACCAGGTAGGTTTAGCCCGCAATGTATCGGCTGCAATTGCTAAAGCCGCAGGATACCGTGATAGAGGCCCTAAAGAGCGTAAAGATTTAGGTGTACTACGCGGGACGAATGCTCCAGCTATCCTGATTGAGTTAGCATTCATCACGAATGCGGATGATATGCGTAAATTCTTCGCTAACATGCAAGCTATTGCAAATGCAATTGTACAAGCCGTAACAGGTAAAACAGTATCAGGAGGTGGTAGCGTGCCGAATAGTGGAGGTAAGTGGGTACTTAAAACAGGTGGAGTTGGCGTCCCTGAAGCACAGGAGTGCATGAACAAGCTCGCAGAGTTCGGGACAAAAGGATCACTAGTGTATGAAGGAAACGGGATTTTCTACGTTATCACCGAGCCAGTAACAGACCGTAATGCTCTAGGTGCTATCAATTGGTATTTCGCTGATTACCGCAAATGGTTTGTAGAGCTGTATCAAGTATAA

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7yZe6) rather than this protein.
PDB ID
7yZe6
Method AlphaFoldv2
Resolution 95.67
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50