Protein

Protein accession
A0A249XPR0 [UniProt]
Representative
8MElA
Source
UniProt (cluster: phalp2_32347)
Protein name
Lysin A, N-acetylmuramoyl-L-alanine amidase domain
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MGYYLADHPNPNAGQYVTQRRGIYGQLSGTVIMHTAEGYGATNVAGFIASRSDYGSYHRLVDPNTIIEMAHWEWETWQDSETNNWAVGISAACRAADWLGIEIQTRLKYYRNLAICAADFVRYMRENYGIEVPRVRISGAQARARVPGFCAHGDSGLSRHDPGVDFDWETFFAMTNEELGEEEDMAISEERFAALENTVKNISDGLFNNNGKNASILGGLSVPGLINKNDVEGIRVDNANTTLILNALKEVSAKLDTLIKK
Physico‐chemical
properties
protein length:261 AA
molecular weight:28945,0 Da
isoelectric point:5,10
hydropathy:-0,35
Representative Protein Details
Accession
8MElA
Protein name
8MElA
Sequence length
333 AA
Molecular weight
36383,30290 Da
Isoelectric point
7,66277
Sequence
MTTGYLLVDQPNPTTPQGTFPRRGTRGKLTGTCIVHTSEGAWQAGVDSLTNQVRTRTDYGCYHRACDWQDIALYYPWEWEAWQDSETNNWAVGIAAACRTSDWAIMPADIREGFYRNMARMAADFVTYMKAEHGITVPLVRLSGEQARAGVPGFCAHGDSGISRTDPGADFNWTLFFTYTRQALAGITAQGGTTAPVKKESEMPTSKRVDSAFKARHRLPKGKAYTLSVKDDGGSANFAVNGAGHYLIHNHIRGEGLLPGQRIKAQFFITKGGKTSGHFAQDIVGTIDGTFDQPVEFNRAVETGTTLTCLLTSSNTETAYITGFGAEVTTWKA
Other Proteins in cluster: phalp2_32347
Total (incl. this protein): 7 Avg length: 304,0 Avg pI: 6,18
Protein ID Length (AA) pI
8MElA 333 7,66277
42xoE 334 6,54310
A0A3G2KER3 333 7,66277
A0A0U4B3G8 270 5,14850
A0A7T3KC70 336 6,10737
A0A9E7MN79 261 5,03886
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_36881
7s6K6
 44 42,2% 218 3.287E-56
2 phalp2_31913
4N8u3
 4 32,9% 237 3.560E-47
3 phalp2_22788
7oqUg
 6 36,4% 203 5.410E-37
4 phalp2_21748
3Ptm0
 18 30,1% 318 1.794E-32
5 phalp2_9231
6Te1j
 3 30,1% 222 4.482E-32
6 phalp2_7699
6IwWh
 11 29,5% 227 8.352E-21
7 phalp2_24092
8fabO
 1 26,8% 242 9.034E-11
8 phalp2_24741
6EXtT
 52 22,7% 215 1.204E-10
9 phalp2_36735
6wX8V
 3 24,2% 219 3.640E-08
10 phalp2_32423
SnuP
 3 20,5% 224 1.337E-04

Domains

Domains [InterPro]
Unannotated
Unannotated
Representative sequence (used for alignment): 8MElA (333 AA)
Member sequence: A0A249XPR0 (261 AA)
1 333 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Arthrobacter phage GurgleFerb
[NCBI] 		2027884 Jasminevirus > Jasminevirus adat
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MF668273 [NCBI]
CDS location
range 14191 -> 14976
strand +
CDS
GTGGGATACTATCTCGCAGATCATCCGAATCCCAATGCGGGTCAGTATGTAACTCAGCGACGTGGTATTTATGGTCAGCTTTCGGGCACCGTAATTATGCACACAGCAGAGGGTTATGGGGCCACAAATGTAGCTGGGTTTATTGCCAGCCGATCTGACTATGGTTCTTACCATCGTTTGGTCGATCCCAATACCATTATTGAAATGGCACATTGGGAATGGGAAACTTGGCAGGATTCGGAAACGAATAACTGGGCTGTGGGAATCTCCGCAGCGTGCAGGGCAGCAGATTGGCTGGGAATTGAAATCCAGACCCGTCTAAAGTATTACCGTAATCTCGCTATTTGTGCGGCTGATTTTGTTCGTTACATGCGTGAGAATTACGGCATTGAAGTTCCACGAGTTCGGATTTCCGGAGCACAGGCTAGGGCACGAGTTCCCGGTTTCTGTGCTCACGGTGATTCCGGACTTTCCCGTCACGATCCCGGCGTTGATTTCGACTGGGAAACATTCTTCGCTATGACTAACGAAGAACTTGGAGAAGAGGAAGATATGGCTATCTCAGAAGAGCGCTTTGCTGCACTCGAAAATACTGTCAAGAATATCTCTGACGGTCTTTTCAACAACAACGGAAAGAACGCTTCCATTCTTGGCGGCCTTTCTGTGCCGGGTCTTATCAACAAGAACGACGTTGAGGGTATTCGGGTAGACAACGCAAACACCACTTTGATTCTCAATGCTCTCAAAGAGGTTTCCGCTAAACTTGATACTCTTATCAAGAAGTAA

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi000bc01773_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (8MElA) rather than this protein.
PDB ID
8MElA
Method AlphaFoldv2
Resolution 87.66
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50