Protein

Protein accession
A0A222ZES2 [UniProt]
Representative
7s5Uq
Source
UniProt (cluster: phalp2_16559)
Protein name
Lysin A
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MTYQLHEEYSCDFTGPERTPLGIAIHWWDDPKNKPTFWNIVNLLLERSRQRSASVNFVAEAGLVACLVSPNVVAWAQGDGASGWGNNNLISIECNPRCTPEDRETVAELIADQRLLWGSLPLYPHNKFTATQCPGVWEQWLPWLDRRANEIMAAKRGQAAPVVPASAPAPAAPAPAPAADNRIHWVVERGDTLGGIAAHYGGPSAAQIAAYNGIPDANRIEVGQRIYIPGPLVWIVDPGDTLGAIGAHYGMSAETVAANNGLNVNAPIFPGQRLRIID
Physico‐chemical
properties
protein length:278 AA
molecular weight:30092,6 Da
isoelectric point:5,37
hydropathy:-0,17
Representative Protein Details
Accession
7s5Uq
Protein name
7s5Uq
Sequence length
244 AA
Molecular weight
27277,26150 Da
Isoelectric point
9,02520
Sequence
MAYRYETQYDSPNYEPGREGNRIQGITIHHWGYDGQYHDDVIRFLCRPGGKTSAHYVVSGGRVTCIISPENTAYHAGTWAANLRQIGIECRPECSRADMETVAELIADLRKTYGYLPLSPHKRFFNTACPGRWESKLGWLDKRAEEIRNGKSTPTQNTGAGGEDRRKKKMRNVGIYWKASDGSVKCAILNTSSGFWAAHSNGNKFLASYNNPLAIAFDTPSWAEVTEAHAAVLQARCEQVRKGA
Other Proteins in cluster: phalp2_16559
Total (incl. this protein): 12 Avg length: 262,3 Avg pI: 6,14
Protein ID Length (AA) pI
7s5Uq 244 9,02520
3e8Vh 272 9,99984
5Sglv 228 4,67179
5kfa3 254 6,96507
6ZDav 266 4,72601
6hkFC 266 4,84055
6oVyd 266 4,71510
7Bz2w 274 8,78087
8hhx8 266 4,66667
8smEf 267 5,00759
JV6i 266 4,85152
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_1064
7bl2o
 2 46,9% 196 9.847E-71
2 phalp2_13682
65xN2
 64 46,9% 162 4.750E-52
3 phalp2_13827
7cMO8
 12 50,3% 155 4.750E-52
4 phalp2_25234
40uRC
 5 49,0% 161 5.831E-51
5 phalp2_31988
59Np4
 130 45,1% 175 4.686E-49
6 phalp2_12749
88ep5
 5 40,6% 160 1.175E-45
7 phalp2_7901
8LrgT
 13 44,6% 159 5.619E-45
8 phalp2_13806
716PV
 1 39,0% 164 1.242E-40
9 phalp2_26331
1cKvm
 65 34,8% 181 2.221E-25
10 phalp2_7058
8iEHQ
 9 35,1% 179 4.117E-25

Domains

Domains [InterPro]
Ami2
Unannotated
Representative sequence (used for alignment): 7s5Uq (244 AA)
Member sequence: A0A222ZES2 (278 AA)
1 244 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Arthrobacter phage Abidatro
[NCBI] 		2015853 Galaxyvirus > Galaxyvirus abidatro
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MF140397 [NCBI]
CDS location
range 18061 -> 18897
strand +
CDS
ATGACTTACCAACTGCACGAGGAGTACTCCTGCGACTTCACCGGGCCGGAGCGGACGCCGCTCGGCATCGCTATTCACTGGTGGGATGATCCAAAGAACAAGCCGACGTTTTGGAACATTGTCAACCTGCTACTCGAGCGGTCCCGGCAGCGGTCCGCCTCGGTCAACTTCGTGGCTGAGGCCGGCCTCGTGGCTTGCCTTGTGTCTCCGAACGTGGTGGCCTGGGCGCAAGGTGACGGGGCCTCCGGCTGGGGCAACAACAACCTGATAAGCATCGAGTGCAACCCTCGGTGCACTCCGGAGGACCGGGAGACGGTCGCGGAGCTTATCGCGGATCAGCGTCTCCTCTGGGGGAGCCTGCCGCTCTACCCTCACAACAAGTTCACGGCGACTCAATGCCCGGGCGTGTGGGAGCAGTGGCTTCCGTGGCTGGACCGGCGGGCCAACGAGATTATGGCGGCTAAGCGCGGGCAGGCGGCTCCGGTAGTTCCGGCCTCCGCTCCTGCTCCGGCCGCTCCGGCTCCTGCCCCTGCGGCCGATAACCGGATCCACTGGGTTGTCGAGCGGGGCGACACGCTCGGCGGGATCGCGGCGCACTACGGCGGCCCGTCTGCGGCGCAGATCGCGGCGTACAACGGCATCCCGGACGCTAACCGGATCGAGGTCGGCCAGCGCATCTACATTCCTGGGCCGCTGGTCTGGATCGTGGACCCTGGCGACACGCTGGGCGCGATCGGGGCGCACTACGGCATGAGCGCGGAGACGGTCGCGGCCAACAACGGCCTGAACGTCAACGCTCCTATCTTCCCGGGGCAGCGGCTCCGGATTATCGACTAA

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi000b94cbd1_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (7s5Uq) rather than this protein.
PDB ID
7s5Uq
Method AlphaFoldv2
Resolution 84.77
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50