Protein

Protein accession
S4S2D7 [UniProt]
Representative
8D2dY
Source
UniProt (cluster: phalp2_35433)
Protein name
Lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MKYRKEDFINKLIAHEGLRLQVYQDSLGIDTIGIGRNLEDRGITKEELEWMDIPNMAIVHTEGITEADAMYLAQNDVQIVEEELVRAHPCVDKLDNVRQLVLMDMAFNMGVPRLCKFKKMWNAIHNEDYANAAKEMLDSRWANQVKSRSTKLANAMHNGEF
Physico‐chemical
properties
protein length:161 AA
molecular weight:18581,1 Da
isoelectric point:5,38
hydropathy:-0,44
Representative Protein Details
Accession
8D2dY
Protein name
8D2dY
Sequence length
313 AA
Molecular weight
N/A Da
Isoelectric point
4,79132
Sequence
mllykrndlidklvvseglrlqvykdtlgidtigigrnledrgitkeeldwmdipnidvvyemgiteadavylatndvqiveeelvrahpcvdsldavrqlivmdmafnmgvprlckfkmmwaaihdedyptaakemldsrwasqvkgratklanamhngefxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxkqqtllnvlfeeaggdlvqakklagyadtsstseivkglkeeileatqmymarnapkaamamvgglydptelgirdkmaaakelldrtglvktekmhveasggvmlmppkavveddd
Other Proteins in cluster: phalp2_35433
Total (incl. this protein): 3 Avg length: 250,3 Avg pI: 5,20
Protein ID Length (AA) pI
8D2dY 313 4,79132
3Cjd 277 5,41706
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_31100
1Wx5S
 2 22,6% 247 6.804E-05

Domains

Domains [InterPro]

No domain annotations available.

Taxonomy

  Name Taxonomy ID Lineage
Phage Puniceispirillum phage HMO-2011
[NCBI] 		948071 No lineage information
Host Candidatus Puniceispirillum marinum IMCC1322
[NCBI] 		488538 Proteobacteria > Alphaproteobacteria > Candidatus Puniceispirillum >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
GU557055 [NCBI]
CDS location
range 45541 -> 46026
strand -
CDS
ATGAAATATCGTAAAGAAGACTTTATCAATAAGTTAATTGCGCACGAAGGTTTGCGCTTACAGGTGTATCAGGATAGCCTTGGTATTGACACTATTGGTATTGGACGGAACCTAGAAGACCGTGGCATCACGAAGGAAGAACTGGAATGGATGGACATACCTAATATGGCTATTGTTCATACTGAAGGTATTACTGAAGCAGATGCTATGTATCTAGCACAGAATGACGTGCAGATTGTCGAAGAAGAACTTGTACGTGCGCACCCTTGCGTAGACAAGCTAGACAATGTACGTCAACTTGTACTTATGGATATGGCATTTAATATGGGTGTGCCACGTCTATGTAAGTTTAAAAAGATGTGGAATGCTATTCATAATGAAGATTATGCCAATGCAGCAAAAGAAATGCTTGACAGCAGGTGGGCAAATCAGGTAAAATCAAGAAGTACAAAATTAGCAAACGCAATGCACAATGGTGAATTTTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		RuleBase:RU003788

Tertiary structure

PDB ID
upi000351f920_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (8D2dY) rather than this protein.
PDB ID
8D2dY
Method AlphaFoldv2
Resolution 83.67
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50