Protein

Protein accession
G8C7W0 [UniProt]
Representative
5aCST
Source
UniProt (cluster: phalp2_16306)
Protein name
Endochitinase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MNQILFQKAAGISAGLAVRWFHYIDAAMKEFGITAPLDQAMFIAQMGHESGGFTRLVENLNYSAENLVSTFGKHRITAQQAAALGRTATQPANQKAIANLVYGGEWGKKNLGNQVAGDGWKYRGRGLKQITGLSNYRNCGHALKLDLVTQPELLEQDEYAARSAAWFYVSHGCLLHSGDVERVTLLINGGRNGLEQRRTLFNLAKSVLV
Physico‐chemical
properties
protein length:209 AA
molecular weight:22922,8 Da
isoelectric point:9,42
hydropathy:-0,20
Representative Protein Details
Accession
5aCST
Protein name
5aCST
Sequence length
212 AA
Molecular weight
22788,68770 Da
Isoelectric point
9,91139
Sequence
MTATAAPRRIDPARFDVFAPKAVRGTLEALEVAADHHGLIDRLALAHWLGQMKVESRGFSVMVESLNYSVVGLIQTFGRHRISAEDCERLGRTPGRPANQEAIANLVYGGAWGRANLGNTEPGDGWRFRGSGFKQITGRANIREAGYETNPEILRTDVRASAMAAANFFVRHGCLAPARADDVKAVTLKVNGGVNGLADRIAATAGARKILL
Other Proteins in cluster: phalp2_16306
Total (incl. this protein): 92 Avg length: 224,9 Avg pI: 9,13
Protein ID Length (AA) pI
5aCST 212 9,91139
11Avg 225 10,07307
11hUs 197 9,47003
15OeX 212 9,25445
15xEx 204 8,96061
1M8cP 213 8,75888
1MCtj 210 8,55903
1OYWs 212 9,29720
1bFkR 198 9,69039
1bUac 207 9,47648
1byff 208 9,42220
1byl9 223 10,02749
1bz7g 208 9,40099
1gzDA 262 9,39964
1hRV2 208 9,51026
1js6i 225 10,07307
1kGWk 208 9,47687
1klyy 257 9,83164
1oCEI 204 8,84160
1rtC8 259 10,05863
20xmj 217 8,60177
2etMF 209 9,43187
2gpfC 213 9,86104
2mQQX 257 10,09789
2pqrT 225 10,06708
2tWvC 207 9,11469
2usat 207 8,95977
2z23u 203 7,93304
345vX 241 9,33078
35d33 256 8,59881
3cVyH 204 9,66589
3d0R7 231 4,68981
3gmOb 201 9,43612
3rzeR 207 7,88102
3vrbT 204 9,43638
4MlKj 247 10,33984
4MsHt 253 10,60100
4Mt27 231 9,68117
4e1wt 221 9,82964
4ftjk 214 6,61966
4fun6 223 8,86158
4funf 229 6,39037
4gS8d 242 9,98320
4kV7b 223 9,18399
4mptS 225 9,98095
4rDVN 240 9,67073
50dSE 241 9,38674
5Errr 237 7,78399
5IPsR 237 8,90213
6AxFX 241 9,47384
6BTrn 201 9,54153
6DWNH 219 9,51594
6HJtB 201 6,20332
6RuBL 226 9,41575
6RyVG 284 8,63865
721PI 227 9,19927
78xTm 252 8,81368
7AyIJ 218 9,09090
7Dg8i 207 7,86226
7UBN7 198 9,69522
7XdK 275 9,39370
7gRqJ 208 9,29726
7kthw 219 9,50414
7m6R3 289 9,68014
7m9k 318 8,97672
7nIP7 209 9,60780
7pYCp 224 9,43967
7poS8 203 9,60677
7stXn 275 9,76930
7vFKc 262 10,06340
7vOSM 207 9,63127
89RdI 207 7,86226
8HmLk 233 8,70583
8LyiG 215 9,03552
8dAyU 198 9,78206
8iJ7C 192 9,39912
8k8XA 236 8,46549
8rSDt 198 9,78206
8ytNi 207 7,86226
QOwS 224 9,01160
ZXQ3 264 10,76695
bpGy 224 5,10473
bs5j 225 10,11330
dga3 241 9,47384
hL6T 249 5,49016
lA4F 223 9,98346
xksP 228 9,75028
A0A482IL61 209 9,79986
A0A2Z2FBK1 209 9,79986
A0A0K1LLX7 233 8,70583
A0A2Z5H035 209 9,54404
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_37433
2Fv3r
 11643 40,3% 191 2.071E-69
2 phalp2_1820
3er8S
 16 38,2% 183 6.736E-65
3 phalp2_24838
7taBM
 21 38,1% 199 2.412E-61
4 phalp2_5234
8cPFI
 3482 33,8% 213 3.304E-61
5 phalp2_10067
7wmbf
 22 36,8% 217 6.951E-59
6 phalp2_2766
23eb
 36 38,2% 191 1.461E-56
7 phalp2_39259
3ZvQn
 35 36,0% 194 2.000E-56
8 phalp2_4675
4GkQr
 23 51,1% 135 8.711E-55
9 phalp2_24275
3cumx
 91 32,0% 206 4.196E-54
10 phalp2_33370
6IDED
 552 31,7% 189 1.825E-52

Domains

Domains [InterPro]
Unannotated
Representative sequence (used for alignment): 5aCST (212 AA)
Member sequence: G8C7W0 (209 AA)
1 212 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Escherichia phage HK639
[NCBI] 		906669 No lineage information
Host Escherichia coli
[NCBI] 		562 Proteobacteria > Gammaproteobacteria > Enterobacteriales > Enterobacteriaceae > Escherichia >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
HM208537 [NCBI]
CDS location
range 45874 -> 46503
strand +
CDS
ATGAACCAAATACTATTTCAAAAGGCGGCAGGTATAAGCGCCGGTCTAGCCGTGCGCTGGTTTCACTATATCGATGCTGCAATGAAGGAATTCGGCATAACCGCGCCGCTCGATCAGGCCATGTTTATCGCGCAGATGGGCCACGAGTCCGGCGGCTTCACCCGGCTGGTGGAAAACCTGAACTATTCGGCAGAAAACCTGGTATCTACGTTTGGCAAGCATCGCATTACTGCACAGCAGGCCGCCGCACTCGGCAGAACGGCAACGCAACCGGCAAATCAAAAAGCGATAGCCAATCTGGTTTATGGCGGTGAGTGGGGCAAAAAGAACCTGGGCAACCAGGTTGCTGGTGATGGCTGGAAATATCGCGGTCGCGGCCTGAAGCAAATCACCGGGCTCAGCAATTACCGCAACTGTGGCCACGCGCTGAAGTTGGACCTTGTAACCCAGCCTGAATTGCTGGAACAGGATGAATATGCTGCGCGCTCCGCTGCATGGTTCTATGTCTCGCACGGATGCCTGCTCCATTCCGGCGACGTGGAGCGCGTGACGCTGCTTATCAACGGCGGCCGTAACGGGCTGGAACAACGGCGCACCCTGTTTAACCTGGCGAAATCTGTGCTGGTGTGA

Gene Ontology

Description Category Evidence (source)
GO:0004568 chitinase activity molecular function None (UniProt)
GO:0006032 chitin catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi00022fb535_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (5aCST) rather than this protein.
PDB ID
5aCST
Method AlphaFoldv2
Resolution 96.30
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50