Protein

Protein accession
A0A2D1GCQ8 [UniProt]
Representative
75PiN
Source
UniProt (cluster: phalp2_23524)
Protein name
Lysin A, glycosyl hydrolase domain
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MDAATLRQALMPTTKSAEDLAPLVSFVENAMEIADIDTVRRAAAWFATIGEETGGFANFVELWGPTAQQRGYEGRADLGNTVSGDGYRFRGRGAIQLTGRNNYREFGKWCVARGLVDDPEHFTKNPDLVATPRWGFLAAAKYWSTTSRKGKTINQWADAGDILAVSRCVNGWVDGVMPWGWPGRQSRYNTCLALGEAILPGGLLMALDAQAQGKILGAAIQTGEAQVTDLEKGVIGPRPQRNTQYYNVDGNPSLAQKGLKLAYLRAMVMDLWNELVYDGYVADVPDPALDSQRYGSPVRFITAIHKNVRQSFLLIRAIAEKVGVDTKAVLEPAPIIEEKK
Physico‐chemical
properties
protein length:340 AA
molecular weight:37250,9 Da
isoelectric point:6,77
hydropathy:-0,25
Representative Protein Details
Accession
75PiN
Protein name
75PiN
Sequence length
575 AA
Molecular weight
61273,82230 Da
Isoelectric point
5,50562
Sequence
MPVSRANVEATKAFIRARLGDPYVYGGALSPTNVKQGTDCSEVCQTALEMALGRYVPGRQAEGATTESYRPVKIGEVGPFGTIRVARPQDIPANAAAKVALHHGPGGGANSHMWMELDGMRIESRGGGVGLITQPRAMAINDPYATAWCYLPGPIVEDGTPMAPEVVTLGQAYENAGERVRQLQLALNAFGAGLDVDGEFGPRTEAAVMAYQRSNGLEADGIAGPLTLAKLGLTFGGTGTPVVTAPADAVALLRRVMTPTEVSNAVLGGYLPYLAEATRAAQINTVRRCAAWYSQLGHESSGLKYMAEIQTNGPGWSDDRRIYRGRGPIQLTWSSNYRKFGQWCAANGYVTDPELFVKQPTLVEQPKWGFLAASWYWLNAGPRPGQINSFADAGDILAVSRCVNGWVDGEMPIGWDDRRTRYLNCMAVGDQMLALAQPATSTDPIEELLMANLEFDSWSLFATPGEPKVPLVNMVRAIDAYIHKVSVSDDAKGGDADALFRIWRAVIGQGRFTDAANVARARAILIDLATESPEVVAFLAAKAAAGDATAKAVLTDVATANPAAVQAFINAQKGA
Other Proteins in cluster: phalp2_23524
Total (incl. this protein): 82 Avg length: 433,4 Avg pI: 6,55
Protein ID Length (AA) pI
75PiN 575 5,50562
1fQks 564 6,18285
3f9DE 521 5,44048
6RrOY 550 6,91022
6RvhB 553 6,12653
72Jhu 467 5,48101
75mUP 465 5,41996
76YF1 457 5,47737
7AI5e 459 6,08640
7AIJ2 526 5,94743
7AIWV 525 5,71814
7AKtP 524 5,77094
7PTVu 491 5,89605
7PVQ9 493 5,78919
7PVmJ 455 6,10379
7PgUm 493 5,67949
7aLyw 573 5,48334
7fYbh 416 5,00504
7fbVd 463 5,33482
7g2dt 362 6,24981
7gVdB 463 5,10979
7hFqs 476 5,29651
7hU5T 466 5,42883
7iKJx 415 5,92407
7iKVp 526 5,93083
7jBG7 526 5,81499
7jBPW 484 5,75406
7jCRp 526 5,89599
7jSI7 474 6,14369
7pH41 463 5,41348
7pH5p 500 5,16720
7pJ1C 463 5,26343
7pKdL 463 5,12701
7pOEt 459 5,29583
7pPQt 459 5,48601
7pPil 500 5,17555
7q59r 500 5,16549
7q5fZ 469 5,59468
7q6EW 457 5,47737
7qHpH 485 5,81334
7qhHD 468 5,68091
7qhUl 474 5,13418
7qiT6 465 5,54859
7qlXK 466 5,54728
7tj1g 475 5,51801
7uhNq 490 5,60065
7uhQe 519 6,25032
7wgCZ 438 6,40640
7y7bV 467 5,48294
8JrkU 540 6,00427
8Jrl1 466 6,21622
8JrlI 491 5,71405
8Jrlz 457 5,75849
A0A2L1IX84 341 8,30599
A0A4Y6EKA7 340 8,59694
A0A410TE38 340 8,32121
A0A0K0N6C3 340 8,27834
Q2TLS9 340 8,96763
G8EJZ6 341 8,28975
A0A385DS23 339 7,66237
A0A385DU67 340 8,59636
A0A386KG47 340 8,59713
A0A386KD63 340 8,83341
A0A5P8DH21 339 6,92313
A0A5Q2WLB8 339 7,68477
A0A411CU33 339 6,46199
A0A142K909 299 6,97564
A0A2D2W4L6 340 8,59700
A0A345L4X6 340 8,59713
A0A385UBV3 340 8,59713
A0A385UFA7 340 8,59713
A0A386KFT4 340 8,59713
A0A410TBH8 340 7,66237
A0A410TDJ6 339 7,68477
A0A7M1CTD5 341 8,59713
A0A7M1RS04 341 8,59713
A0A9E7NHC3 340 8,32121
A0A9E8M2W2 341 8,28988
A0AAE7VCV6 340 8,59636
A0AAF0GIH1 340 8,28053
A0AAF0K1V0 340 8,31051
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_1467
1Mw6C
 71 40,0% 534 8.783E-151
2 phalp2_6665
1IZIA
 9 21,8% 544 1.332E-65

Domains

Domains [InterPro]
Unannotated
PG_1
Unannotated
Unannotated
Representative sequence (used for alignment): 75PiN (575 AA)
Member sequence: A0A2D1GCQ8 (340 AA)
1 575 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01471

Taxonomy

  Name Taxonomy ID Lineage
Phage Gordonia phage Kabluna
[NCBI] 		2041511 Zierdtviridae > Kablunavirus > Kablunavirus kabluna
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MF919510 [NCBI]
CDS location
range 37421 -> 38443
strand +
CDS
ATGGACGCCGCCACGCTGCGCCAGGCGCTCATGCCGACGACCAAGTCGGCCGAAGACCTGGCTCCTCTCGTCTCCTTCGTGGAGAACGCGATGGAGATCGCCGACATCGACACTGTGCGCCGCGCCGCCGCGTGGTTCGCGACGATTGGCGAAGAGACCGGAGGGTTCGCGAACTTCGTCGAGCTGTGGGGCCCGACCGCGCAGCAACGCGGGTACGAGGGCCGGGCCGATCTCGGGAACACCGTGTCCGGGGACGGCTACCGGTTCCGCGGCCGAGGGGCCATCCAGCTCACCGGTCGGAACAACTACCGAGAGTTCGGAAAGTGGTGTGTCGCAAGGGGTCTGGTCGATGACCCCGAACATTTCACGAAGAACCCGGACCTCGTCGCGACGCCGCGGTGGGGGTTCCTCGCGGCGGCAAAGTACTGGTCGACGACCTCGCGCAAGGGGAAGACGATCAACCAGTGGGCCGACGCCGGGGACATCCTGGCTGTCAGCCGATGTGTCAACGGCTGGGTCGACGGGGTAATGCCCTGGGGATGGCCTGGGCGACAATCGCGTTACAACACGTGTCTCGCGCTCGGCGAGGCGATCCTACCGGGAGGTTTACTCATGGCACTCGACGCACAGGCACAGGGGAAGATCCTCGGCGCCGCGATTCAGACCGGCGAAGCCCAGGTCACGGACCTGGAGAAGGGTGTGATCGGCCCGCGGCCGCAGCGCAACACCCAGTACTACAACGTCGACGGCAACCCTTCGTTGGCGCAGAAGGGGCTGAAGCTCGCCTACCTGCGCGCGATGGTCATGGACCTCTGGAACGAGCTGGTCTACGACGGTTACGTGGCCGACGTGCCGGACCCCGCACTCGACAGCCAGCGCTACGGCTCGCCGGTGCGATTCATCACCGCGATCCACAAGAACGTGCGGCAGAGCTTCCTGCTCATCCGCGCCATCGCCGAGAAGGTCGGCGTCGACACCAAGGCCGTGCTCGAACCGGCCCCCATCATCGAGGAGAAGAAGTGA

Gene Ontology

Description Category Evidence (source)
GO:0016787 hydrolase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi000c0c5291_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (75PiN) rather than this protein.
PDB ID
75PiN
Method AlphaFoldv2
Resolution 86.24
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50