Protein

Protein accession
W8CZD4 [UniProt]
Representative
5Hmxa
Source
UniProt (cluster: phalp2_6173)
Protein name
Lytic transglycosylase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MRIFTLWLSTLLLTLGLLTAPAMATTSTGPVKVNYAGMEKYGKLVLQVANQTGVDPMELVTFISIESKFNPKAKNGEGSSAAGMGAFIDSTWLAMLKTYGKKYGLSMKTRKSNPRANLLMTAEYIKENRGILESRLGRPVSTAEVYTAHLLGPGGAMKILSAKSNRVAYQAARTSPSKNKRYFLKENGKPRTVAEFRKFTRQMVESHKRAYREITMLTAFEHQMEFVTASRT
Physico‐chemical
properties
protein length:232 AA
molecular weight:25775,8 Da
isoelectric point:10,20
hydropathy:-0,28
Representative Protein Details
Accession
5Hmxa
Protein name
5Hmxa
Sequence length
311 AA
Molecular weight
34115,77360 Da
Isoelectric point
9,48551
Sequence
MTKSTTNLLEVAFFALLAFVIGILTRPDSAPTQTPHQSIAAVTSVTMPTLSDTPVKPLTPAQQSIAHSVLHSETLYPVEQRFPAPHYSTLPMPTNEGDWNGYKLMIVMAAKYADVDPAYMAATAGRESNFVATAQPISNKRAVSSATGVYQFIDSTWNTMVKRYGAQYGITLKTPKTDPRANALMGAEYAKENKAYLESILHRKIQPTEMYMAHLLGAGGALSIIKARSTALAINVRPDAVSGNRALFYSTVNGVSKPVTVYEFRKRLRQHTAKLQKLYGESAIAYSDLLSGTDRLKPMVINYQYETNPMA
Other Proteins in cluster: phalp2_6173
Total (incl. this protein): 6 Avg length: 239,3 Avg pI: 10,16
Protein ID Length (AA) pI
5Hmxa 311 9,48551
A0A5P8D301 219 10,29981
A0AA96NML5 225 10,30110
A0AAE7SJA7 217 10,47993
A0AAE9VS31 232 10,19911
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_29643
8s2FN
 29 37,1% 194 4.210E-49
2 phalp2_38503
1qEIR
 8 33,8% 189 5.844E-42
3 phalp2_3993
7AmnE
 31 34,8% 198 4.704E-34
4 phalp2_31726
3OtGv
 26 30,5% 190 3.084E-21

Domains

Domains [InterPro]
Unannotated
Representative sequence (used for alignment): 5Hmxa (311 AA)
Member sequence: W8CZD4 (232 AA)
1 311 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Erwinia phage PhiEaH1
[NCBI] 		1401669 Iapetusvirus > Iapetusvirus EaH1
Host Erwinia amylovora
[NCBI] 		552 Proteobacteria > Gammaproteobacteria > Enterobacteriales > Enterobacteriaceae > Erwinia >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
KF623294 [NCBI]
CDS location
range 38344 -> 39042
strand -
CDS
ATGCGCATCTTTACGCTCTGGCTCAGCACCCTTTTGCTGACCCTTGGCCTGTTAACGGCACCGGCAATGGCGACCACCAGTACCGGACCCGTGAAGGTCAATTACGCCGGGATGGAGAAGTACGGCAAGTTAGTGTTACAAGTCGCTAACCAAACCGGGGTCGACCCGATGGAGCTGGTGACCTTCATCAGCATTGAGTCGAAGTTCAACCCCAAAGCAAAGAACGGTGAGGGTAGTAGCGCTGCCGGAATGGGTGCCTTTATTGACAGCACCTGGCTCGCGATGCTAAAGACGTACGGGAAAAAATATGGGCTTTCCATGAAGACTCGGAAATCCAATCCCCGCGCCAACCTGCTTATGACTGCCGAATACATCAAGGAGAACCGTGGTATCCTGGAGAGTCGACTTGGTCGGCCTGTTAGTACCGCCGAGGTTTATACCGCCCACCTGCTAGGACCAGGCGGAGCGATGAAAATCCTGAGTGCCAAAAGTAATCGCGTCGCCTATCAAGCGGCCCGAACATCACCGTCGAAAAATAAACGGTATTTCCTGAAAGAGAATGGGAAGCCACGGACTGTAGCTGAATTTCGCAAGTTCACCCGCCAGATGGTTGAGAGCCATAAGCGAGCCTACCGCGAGATTACCATGCTGACTGCCTTCGAGCACCAGATGGAATTTGTTACAGCCTCACGAACCTAA

Gene Ontology

No Gene Ontology terms available.

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (5Hmxa) rather than this protein.
PDB ID
5Hmxa
Method AlphaFoldv2
Resolution 76.06
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50